Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 334 time(s) and present in 276 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
COLColombia Sierra Nevada de Santa Marta Kogi pop 30.613031See
COLColombia Sierra Nevada de Santa Marta Kogi0.552042See
COLColombia North Wiwa El Encanto0.538552See
MEXMexico Mayan0.533016See
COLColombia North Chimila Amerindians0.531947See
MEXMexico Sinaloa Capomos Mayo Yoremes0.508360See
MEXMexico Sonora Seri0.470034See
COLColombia Sierra Nevada de Santa Marta Arsario0.450018See
MEXMexico Huasteca Region Teenek0.398055See
MEXMexico San Vicente Tancuayalab Teenek/Huastecos0.396253See
GTMGuatemala Mayan0.3860132See
CRICosta Rica Amerindians (G)55.00.3540125See
COLColombia Jaidukama0.327039See
ARGArgentina Chubut Tehuelche0.325023See
MEXMexico Oaxaca Mixtec0.2910103See
ECUEcuador Cayapa0.2870183See
MEXMexico Mazatecan0.281089See
MEXMexico Veracruz Xalapa44.00.273884See
CRICosta Rica and Panama Mestizo0.250056See
ARGArgentina Mapuche0.244048See
MEXMexico Chiapas Lacandon Mayans0.2385218See
ARGArgentina Rio Negro Mapuche0.205034See
COLColombia West Embera0.200020See
MEXMexico Oaxaca Jamiltepec Mixtec0.193096See
MEXMexico Mixtec0.191097See
USAUSA South Dakota Lakota Sioux0.1880302See
MEXMexico Nahua/Aztec Santo Domingo Ocotitlan0.184973See
MEXMexico Oaxaca Mixe0.182055See
NICNicaragua Managua31.40.1796339See
NICNicaragua Mestizo (G)31.90.1690155See
PERPeru Lamas City Lama0.169083See
MEXMexico Mexico City Tlalpan30.00.1667330See
COLColombia Sierra Nevada de Santa Marta Arhuaco0.1630107See
MEXMexico Jaltepec Mazahuas0.160050See
MEXMexico Mazahua0.160065See
COLColombia West Waunana0.150030See
CRICosta Rica Guanacaste Mestizo (G)27.30.1500110See
ESPSpain Northwest27.60.14911818See
MEXMexico Mexico City Mestizo pop 30.1480256See
PERPeru Quechua0.148044See
MEXMexico Highlands Mestizos27.50.1410160See
USAUSA South Dakota Sioux0.1410101See
COLColombia Wayu from Guajira Peninsula0.135448See
MEXMexico Guanajuato and Jalisco Mestizo25.70.1290101See
COLColombia Bogotá Cord Blood22.80.12271463See
COLColombia Northwest Tule0.121029See
ECUEcuadorean Amerindians0.120075See
BOLBolivia/Peru Quechua NA-DHS_12 (G)23.80.119021See
MEXMexico Mexico City Mestizo pop 20.1175234See
COLColombia Sierra Nevada de Santa Marta Ijka pop 20.117030See
MEXMexico Oaxaca Zapotec0.114090See
PERPeru Titikaka Lake Uros0.1100105See
PERPeru Titikaka Lake Uro0.1090105See
BOLBolivia La Paz Aymaras0.109087See
COLColombia Guajira Peninsula Wayuu0.107088See
MEXMexico Chihuahua Chihuahua City Pop 218.20.102388See
COLColombia Bogota and Medellin Mestizo0.100065See
MEXMexico Mayan pop 20.0960163See
MEXMexico Mexico City Mestizo population0.0944143See
CHLChile Santiago Mixed18.00.094470See
CRICosta Rica Central Valley Mestizo (G)16.80.0930221See
COLColombia North Eastern Plains Sikuani0.093027See
MEXMexico Nuevo Leon Mestizo17.50.089040See
BRABrazil Guarani Kaiowa0.0840155See
ARGArgentina Rosario Toba16.30.081086See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.08101058See
BOLBolivia Quechua0.079769See
BRABrazil Central Plateau Xavante0.077074See
USAUSA South Texas Hispanic0.0770194See
USAUSA NMDP Hispanic South or Central American0.0748146714See
USAUSA NMDP Mexican or Chicano0.0747261235See
USAUSA Hispanic pop 20.06431999See
USAUSA Southern California Mestizo12.30.063573See
ARGArgentina Gran Chaco Eastern Toba0.0620135See
ARGArgentina Gran Chaco Western Toba Pilaga0.061019See
CHLChile Santiago0.0606920See
USAUSA Mexican American Mestizo pop 30.0560116See
ARGArgentina Chiriguano10.70.054054See
IRNIran Yazd Zoroastrian0.054065See
BRABrazil Terena10.20.051060See
COLColombia West Cauca0.050020See
COLColombia Northwest Choco0.050020See
USAUSA NMDP North American Amerindian0.048635791See
USAUSA NMDP American Indian South or Central America0.04605926See
USAUSA New Mexico Canoncito Navajo0.038042See
COLColombia Providencia Island African0.033030See
CHLChile Mapuche0.030866See
USAUSA New Mexico Zuni0.030051See
CHNChina, Xinjiang Uyghur Autonomous Region Hui5.90.029440See
ESPSpain Tenerife Island0.029083See
USAUSA Arizona Pima pop20.029018See
ZAFSouth Africa Caucasians0.0270102See
USAUSA San Antonio Caucasian0.0270222See
PRTAzores Oriental Islands0.026043See
CANCanada British Columbia Athabaskan0.024062See
VENVenezuela Sierra de Perija Yucpa0.023073See
USAUSA NMDP Caribean Hispanic0.0224115374See
PRTPortugal North0.022046See
ISRIsrael Kavkazi Jews0.02032840See
PRTPortugal Center0.020050See
USAUSA San Diego3.60.0200496See
BRABrazil Mixed0.0200108See
ARMArmenia combined Regions0.0200100See
USAUSA NMDP Alaska Native or Aleut0.02001376See
ARGArgentina Buenos Aires3.90.0190466See
NIRIreland Northern3.40.01801000See
USAUSA NMDP Caribean Indian0.018014339See
USAUSA Caucasian pop 50.0170268See
USAUSA Arizona Gila River Amerindian0.0170492See
USAUSA Caucasian pop 40.01541070See
COLColombia Antioquia Paisa0.0150100See
JPNJapan Hokkaido Wajin2.80.014171See
IRLIreland South2.40.0140250See
PRTPortugal Azores Terceira Island2.60.0132130See
MKDMacedonia pop 10.0130158See
USAUSA Caucasian Houston2.60.0130194See
CHNChina, Xinjiang Uyghur Autonomous Region Han2.50.012570See
BRABrazil Southeast Mixed Race2.40.012042See
BRABrazil Guarani Nandeva0.012086See
BRABrazil North East Mixed0.0120205See
PRTAzores Terceira Island0.0120130See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.01203830See
DEUGermany DKMS - United Kingdom minority0.01201043See
USAUSA NMDP European Caucasian0.01121242890See
USAUSA Philadelphia Caucasian2.10.0110141See
ESPSpain Barcelona2.20.0110941See
JPNJapan Aichi2.20.011050See
USAUSA Caucasian2.10.010561655See
DEUGermany DKMS - Portugal minority0.01021176See
FRAFrance West2.00.0100100See
BRABrazil Mato Grosso do Sul0.0100203See
CHNChina Yunnan Province Han0.0100101See
CRICosta Rica African -Caribbean (G)2.00.0100102See
TURTurkey pop 10.0100250See
SCOScotland Orkney1.90.010099See
PRTPortugal South0.010049See
POLPoland Wielkopolska Region0.010099See
USAUSA Eastern European0.0100558See
DEUGermany DKMS - Netherlands minority0.00981374See
DEUGermany pop 31.80.0090111See
FRAFrance South0.0090350See
INDIndia North pop 20.009072See
NLDNetherlands Leiden0.00901305See
USAUSA Southeast African American0.90.0090112See
JPNJapan Central0.0090371See
USAUSA San Francisco Caucasian0.0090220See
USAUSA Caucasian Pittsburgh1.80.0090177See
USAUSA Minnesota Olmsted0.0090339See
DEUGermany DKMS - Spain minority0.00861107See
DEUGermany DKMS - France minority0.00851406See
DEUGermany pop 60.00838862See
USAUSA NMDP Hawaiian or other Pacific Islander0.008011499See
ESPSpain Murcia0.0080173See
ITAItaly Central0.0080380See
JPNJapan Hyogo Osaka and Nagano0.0080195See
JPNJapan pop 61.60.0080129See
SWESweden Southern Sami0.0080130See
RUSRussia Tuva pop 20.0080169See
RUSRussia Tuva0.0080190See
DEUGermany DKMS - Greece minority0.00791894See
DEUGermany DKMS - Austria minority0.00771698See
DEUGermany DKMS - Turkey minority0.00724856See
DEUGermany DKMS - German donors0.00723456066See
USAUSA NMDP Middle Eastern or North Coast of Africa0.007170890See
CUBCuba Mixed0.007078See
ESPSpain Arratia Valley Basque0.007083See
INDIndia Northeast Mathur0.0070155See
RUSRussia Siberia Khanty Mansi0.007068See
SVNSlovenia pop 21.40.0070140See
KORSouth Korea pop 110.0070149See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,1.40.00694335See
DEUGermany pop 80.006939689See
BRABrazil South Caucasian0.006973See
FRAFrance French Bone Marrow Donor Registry0.006742623See
USAUSA NMDP Japanese0.006424582See
DEUGermany DKMS - Italy minority0.00651159See
ESPSpain North Cantabria0.006083See
GRCGreece pop 81.20.006083See
USAUSA Colorado Univ Cord Blood Bank African American0.0060261See
MKDMacedonia pop 20.006080See
JPNJapan pop 160.005718604See
JPNJapan pop 170.00523078See
CZECzech Republic NMDR0.00525099See
MYSMalaysia Peninsular Chinese1.00.0052194See
TUNTunisia pop 30.0050104See
RUSRussia Northwest Slavic0.0050200See
JPNJapan pop 30.00501018See
ITAItaly Bergamo1.00.0050101See
ITAItaly Rome1.00.0050100See
IRNIran Azeri0.0050100See
IRNIran pop 30.0050100See
LBNLebanon Kafar Zubian0.005094See
KORSouth Korea pop 21.00.0050207See
KORSouth Korea pop 30.0050485See
ESPSpain North Cabuerniga0.005095See
ESPSpain Pas Valley0.005088See
ESPSpain Andalusia0.005099See
ESPSpain Granada0.0050280See
INDIndia Northeast Sunni0.0050188See
INDIndia Uttar Pradesh0.0050202See
HRVCroatia Krk Island0.0050212See
BRABrazil Southeast Caucasian1.00.0050103See
CHNChina Lijiang Naxi0.0050100See
CHNChina Beijing Shijiazhuang Tianjian Han0.0050618See
USAUSA African American pop 70.0050193See
DEUGermany DKMS - Romania minority0.00451234See
USAUSA NMDP Korean0.004477584See
GEOGeorgia Caucasus Tbilisi0.0042119See
GRCGreece pop 60.0041242See
GRCGreece pop30.80.0040246See
POLPoland DKMS0.004120653See
ITAItaly pop 50.0040975See
JPNJapan pop 20.0040916See
JPNJapan pop 40.80.0040525See
USAUSA African American pop 40.00402411See
USAUSA NMDP African American pop 20.0039416581See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00391028See
ESPSpain Northwest Lugo0.70.0035145See
KORSouth Korea pop 100.00354128See
ISRIsrael Georgia Jews0.00314471See
JPNJapan Kyoto and Osaka0.0030165See
KORSouth Korea pop 10.0030324See
DEUGermany Essen0.60.0030174See
FINFinland pop20.0030150See
INDIndia Northeast Vaish0.0030198See
INDIndia Northeast Shia0.0030190See
CHNChina Harbin Manchu0.0030172See
CHNChina Jiangsu Han0.00303238See
USAUSA Caucasian Bethesda0.60.0030307See
DEUGermany DKMS - Croatia minority0.00292057See
USAUSA NMDP Caribean Black0.002933328See
HRVCroatia pop 40.00274000See
KORSouth Korea pop 40.50.0025211See
USAUSA NMDP African0.002428557See
DEUGermany DKMS - China minority0.00231282See
CHNChina Canton Han0.0020264See
KORSouth Korea pop 60.0020800See
USAUSA Alaska Yupik0.0020252See
TWNTaiwan Han Chinese0.0020504See
ISRIsrael USSR Jews0.001945681See
RUSRussia Karelia0.00191075See
ISRIsrael Arab pop 20.001712301See
CHNChina Hubei Han0.40.00173732See
ISRIsrael Argentina Jews0.00164307See
ISRIsrael USA Jews0.00146058See
USAUSA Asian pop 20.00141772See
USAUSA NMDP Southeast Asian0.001327978See
USAUSA NMDP South Asian Indian0.0013185391See
LKASri Lanka Colombo0.30.0010714See
CHNChina Marrow Donor Registry0.0010600See
USAUSA NMDP Vietnamese0.000943540See
USAUSA NMDP Filipino0.000950614See
ISRIsrael Poland Jews0.000813871See
USAUSA NMDP Chinese0.000899672See
BRABrazil Paraná Caucasian0.20.0008641See
ISRIsrael Ashkenazi Jews pop 30.00084625See
CHNChina Zhejiang Han pop 20.0006833See
INDIndia Tamil Nadu0.00042492See
HKGHong Kong Chinese BMDR0.00037595See
HKGHong Kong Chinese cord blood registry0.00033892See
ISRIsrael Iraq Jews0.000213270See
ISRIsrael Tunisia Jews0.00019070See
ISRIsrael Morocco Jews0.000136718See
ISRIsrael Moroccan Jews0.0000113See
ISRIsrael Ashkenazi Jews pop 20.0000132See
IRNIran Kurd0.0000100See
ITAItaly North pop 30.00.000097See
JPNJapan South0.00.0000125See
JPNJapan pop 110.00.000062See
JPNJapan Nagano0.00.000057See
MARMorocco Nador Metalsa0.000099See
MARMorocco Settat Chaouya0.000098See
LBNLebanon Niha el Shouff0.000061See
LBNLebanon Yuhmur0.000082See
RUSRussia Siberia Ulchi0.000073See
RUSRussia Siberia Negidal0.000035See
RUSRussia Siberia Khabarovsk Evenki0.000025See
RUSRussia Tuva pop30.000044See
RUSRussia Tuva Todja0.000022See
RUSRussia Siberia Irkutsk Tofalar0.000043See
RUSRussia Siberia Kushun Buryat0.000025See
PRYParaguay Aché0.000087See
PRYParaguay Lengua0.000017See
PRTAzores Central Islands0.000059See
PNGPapua New Guinea Lowland0.000047See
PNGPapua New Guinea Lowland Wosera0.000079See
PNGPapua New Guinea Highland0.000094See
MNGMongolia Hoton0.000085See
MNGMongolia Khalkha pop 20.0000202See
INDIndia Northeast Kayastha0.0000190See
INDIndia Northeast Rastogi0.0000196See
IRNIran Fars Parsi0.000073See
INDIndia Northeast Lachung0.000058See
INDIndia Northeast Mech0.000063See
INDIndia Northeast Rajbanshi0.000098See
INDIndia North0.00.000085See
IDNIndonesia Nusa Tenggara Islands0.000049See
IDNIndonesia Moluccan Islands0.000024See
IDNIndonesia Singaporean0.000050See
FRAFrance Rennes0.0000200See
GRCGreece pop 40.000098See
DZAAlgeria pop 20.00.0000106See
CZECzech Republic0.0000106See
CHNChina Urumqi Uyghur0.00.000057See
CANCanada British Columbia Penutian0.000026See
CHNChina Harbin Korean0.0000201See
CODCongo Kinshasa Bantu0.00.000090See
COKCook Islands0.000050See
BRABrazil East Amazon0.000041See
CAFCentral African Republic Aka Pygmy0.00.000093See
BRABrazil Kaingang0.0000235See
BRABrazil Guarani M bya0.000093See
ARGArgentina Salta Wichi0.000024See
ARGArgentina Gran Chaco Mataco Wichi0.000049See
USAUSA African American Bethesda0.00.0000187See
USAUSA Colorado Univ Cord Blood Bank Asian0.0000100See
WSMSamoa pop20.000050See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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