Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 338 time(s) and present in 295 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ISRIsrael Iraq Jews0.338813270See
ISRIsrael Iran Jews0.29848153See
ISRIsrael Georgia Jews0.24244471See
LBNLebanon Kafar Zubian0.237094See
ISRIsrael Tunisia Jews0.23229070See
ISRIsrael Druze0.23075914See
ISRIsrael Kavkazi Jews0.21492840See
ISRIsrael Iranian Jews0.2100101See
ISRIsrael Bukhara Jews0.20092317See
HRVCroatia Krk Island Dubasnica0.196023See
HRVCroatia Krk Island Vrbnik0.196028See
GRCGreece pop 40.193098See
GRCGreece pop334.10.1882246See
GRCGreece pop 60.1860242See
ISRIsrael Arab pop 20.185712301See
MKDMacedonia pop 20.180080See
ISRIsrael Poland Jews0.178113871See
ISRIsrael USA Jews0.17636058See
ISRIsrael Ashkenazi Jews pop 30.17524625See
ISRIsrael Libya Jews0.17393739See
LBNLebanon Niha el Shouff0.170061See
ITAItaly Rome33.00.1700100See
GRCGreece pop 828.90.168783See
ISRIsrael Argentina Jews0.16654307See
MKDMacedonia pop 30.1660172See
ISRIsrael Morocco Jews0.164036718See
ISRIsrael USSR Jews0.162645681See
ITAItaly pop 428.10.15204575See
ISRIsrael Non Ashkenazi Jews0.149080See
ESPSpain North Cabuerniga0.142095See
DEUGermany DKMS - Greece minority0.13911894See
MKDMacedonia pop 10.1390158See
HRVCroatia Krk Island0.1320212See
LBNLebanon Yuhmur0.130082See
ISRIsrael Ashkenazi Jews pop 20.1250132See
GRCGreece pop223.40.1250120See
USAUSA NMDP Middle Eastern or North Coast of Africa0.120470890See
ISRIsrael Moroccan Jews0.1190113See
ARMArmenia combined Regions0.1150100See
DEUGermany DKMS - Italy minority0.10871159See
DEUGermany DKMS - Turkey minority0.10724856See
ISRIsrael Libyan Jews0.1070119See
ITAItaly Central0.1030380See
ITAItaly pop 50.1000975See
GRCGreece Crete0.1000135See
GAZGaza Palestinians0.0970165See
ISRIsrael Arab0.0960109See
ISRIsrael Yemenite Jews0.090076See
CHNChina Beijing and Xian0.0880171See
ISRIsrael Ashkenazi Jews0.085080See
CHESwitzerland Geneva pop 20.08151267See
DEUGermany DKMS - Romania minority0.07941234See
DEUGermany DKMS - Croatia minority0.07792057See
HRVCroatia pop 40.07664000See
ESPSpain North Cantabria0.072083See
DEUGermany DKMS - Bosnia and Herzegovina minority0.06861028See
FRAFrance West13.00.0672100See
ITAItaly North pop 313.40.067097See
ESPSpain Andalusia0.066099See
CHNChina, Xinjiang Uyghur Autonomous Region Uyghur13.00.065271See
ESPSpain Pas Valley0.065088See
MEXMexico Nuevo Leon Mestizo12.50.063040See
PNGPapua New Guinea Madang0.062065See
TURTurkey pop 10.0620250See
SVNSlovenia pop 212.00.0619140See
CHESwitzerland Basel0.06141888See
ESPSpain Murcia0.0600173See
USAUSA Philadelphia Caucasian10.60.0600141See
CHESwitzerland Luzern0.05991553See
USAUSA Eastern European0.0580558See
ISRIsrael YemenJews0.057415542See
MYSMalaysia Mandailing11.10.056027See
USAUSA South Texas Hispanic0.0560194See
GEOGeorgia Caucasus Tbilisi0.0546119See
ESPSpain Barcelona10.60.0540941See
ESPSpain Arratia Valley Basque0.053083See
INDIndia Delhi0.0530112See
CZECzech Republic pop 210.10.051899See
CHESwitzerland Lausanne0.0518993See
BRABrazil Paraná Caucasian10.00.0507641See
COLColombia West Cauca0.050020See
CHESwitzerland Aargau-Solothurn0.04971838See
CHESwitzerland Lugano0.04691169See
CZECzech Republic NMDR0.04675099See
TUNTunisia pop 30.0440104See
ARGArgentina Rio Negro Mapuche0.044034See
USAUSA Caucasian Pittsburgh8.80.0440177See
CHESwitzerland Sion0.0432832See
CZECzech Republic0.0430106See
FRAFrance Southeast8.50.0430130See
POLPoland DKMS0.042120653See
CHESwitzerland Bern0.04163545See
PRTPortugal South0.041049See
ITAItaly Bergamo7.90.0410101See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,7.90.04054335See
DEUGermany DKMS - Spain minority0.04041107See
CHESwitzerland St Gallen0.04032113See
BRABrazil Southeast Caucasian7.80.0390103See
USAUSA Caucasian pop 50.0390268See
PRTAzores Oriental Islands0.038043See
TUNTunisia Matmata Berber0.037081See
ZAFSouth Africa Caucasians0.0370102See
ARGArgentina Gran Chaco Eastern Toba0.0370135See
TUNTunisia Ghannouch0.037082See
COLColombia San Basilio de Palenque0.036042See
DEUGermany pop 80.036039689See
PRTAzores Central Islands0.036059See
CHESwitzerland Zurich0.03544875See
ESPSpain Las Alpujarras0.035385See
MNGMongolia Hoton0.035085See
MNGMongolia Tarialan Khoton0.035085See
MEXMexico Mexico City Mestizo population0.0350143See
DEUGermany Essen6.90.0350174See
DZAAlgeria Oran0.0350100See
BRABrazil Guarani Nandeva0.035086See
BRABrazil Mixed0.0350108See
DEUGermany DKMS - Austria minority0.03461698See
CHESwitzerland Graubunden0.0343759See
DEUGermany DKMS - France minority0.03411406See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.03401058See
FRAFrance French Bone Marrow Donor Registry0.033742623See
CHLChile Santiago0.0330920See
RUSRussia Karelia0.03291075See
USAUSA NMDP Mexican or Chicano0.0325261235See
TZATanzania Maasai6.40.0321336See
MEXMexico Mayan pop 20.0310163See
PRTAzores Terceira Island0.0310130See
ARGArgentina Buenos Aires6.30.0310466See
PRTPortugal Azores Terceira Island5.30.0307130See
DZAAlgeria pop 26.00.0304106See
CRICosta Rica and Panama Mestizo0.030056See
MEXMexico Guanajuato and Jalisco Mestizo5.90.0300101See
PRTPortugal Center0.030050See
RUSRussia Chuvash0.030082See
DEUGermany pop 60.02998862See
USAUSA NMDP European Caucasian0.02951242890See
DEUGermany DKMS - German donors0.02913456066See
ESPSpain Tenerife Island0.029083See
AREUnited Arab Emirates Abu Dhabi0.028852See
DEUGermany DKMS - Portugal minority0.02821176See
USAUSA Caucasian Bethesda5.60.0280307See
USAUSA NMDP Hispanic South or Central American0.0280146714See
MEXMexico Chiapas Lacandon Mayans0.0275218See
DEUGermany pop 35.40.0273111See
BRABrazil Mato Grosso do Sul0.0270203See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.02703830See
USAUSA San Diego4.60.0260496See
USAUSA NMDP Caribean Hispanic0.0258115374See
USAUSA Hispanic pop 20.02551999See
USAUSA Minnesota Olmsted0.0250339See
USAUSA Caucasian4.90.024861655See
USAUSA NMDP Southeast Asian0.024027978See
SAUSaudi Arabia Guraiat and Hail4.80.0240213See
PERPeru Lamas City Lama0.024083See
MEXMexico Veracruz Xalapa4.80.023884See
USAUSA Caucasian pop 40.02311070See
USAUSA San Francisco Caucasian0.0230220See
ENGEngland Bedfordshire4.50.0227354See
DEUGermany DKMS - Netherlands minority0.02261374See
NICNicaragua Managua4.50.0225339See
MEXMexico Highlands Mestizos4.40.0220160See
RUSRussia Siberia Khanty Mansi0.022068See
CODCongo Kinshasa Bantu4.40.022090See
USAUSA Mexican American Mestizo pop 30.0220116See
USAUSA NMDP Caribean Indian0.021014339See
USAUSA San Antonio Caucasian0.0203222See
CHLChile Santiago Mixed4.00.020270See
PRTMadeira pop 20.0200173See
USAUSA NMDP American Indian South or Central America0.02005926See
COLColombia Bogotá Cord Blood3.90.01981463See
USAUSA NMDP South Asian Indian0.0197185391See
DEUGermany DKMS - United Kingdom minority0.01931043See
GEOGeorgia Svaneti Region Svan0.019080See
BRABrazil North East Mixed0.0190205See
NZLNew Zealand Polynesians with Admixed History3.70.019027See
MEXMexico Mexico City Mestizo pop 30.0190256See
NLDNetherlands Leiden0.01801305See
SDNSudan Mixed3.50.0180200See
INDIndia North3.50.017685See
MEXMexico Mexico City Mestizo pop 20.0171234See
MEXMexico Chihuahua Chihuahua City Pop 23.40.017088See
PNGPapua New Guinea East New Britain Rabaul0.017060See
INDIndia Northeast Lachung0.017058See
COLColombia Providencia Island African0.017030See
COLColombia Sierra Nevada de Santa Marta Ijka pop 20.017030See
USAUSA NMDP North American Amerindian0.016335791See
USAUSA Caucasian Houston3.20.0160194See
CHNChina Xinjiang Province Uyghur0.016092See
NLDNetherlands UMCU3.10.015664See
CHNChina, Xinjiang Uyghur Autonomous Region Kazakh3.00.015252See
CHNChina Yunnan Province Han0.0150101See
POLPoland Wielkopolska Region0.015099See
RUSRussia Northwest Slavic0.0150200See
RUSRussia Bering Island Aleuts0.0144104See
SCOScotland Orkney2.90.014099See
USAUSA NMDP Alaska Native or Aleut0.01401376See
USAUSA NMDP Hawaiian or other Pacific Islander0.013111499See
RUSRussia Tuva0.0130190See
NIRIreland Northern2.50.01301000See
CHNChina, Xinjiang Uyghur Autonomous Region Han2.50.012570See
CHNChina Yunnan Province Han pop 20.0120129See
MNGMongolia Ulaanbaatar Khalkha0.012041See
PRTPortugal North0.011046See
IDNIndonesia Singaporean0.010050See
USAUSA Colorado Univ Cord Blood Bank African American0.0100261See
USAUSA Colorado Univ Cord Blood Bank Asian0.0100100See
USAUSA South Dakota Sioux0.0100101See
USAUSA NMDP African0.009128557See
MEXMexico Mexico City Tlalpan1.80.0091330See
USAUSA NMDP Caribean Black0.009133328See
MYSMalaysia Sabah Kadazan0.009057See
SGPSingapore Riau Malay0.0090132See
ESPSpain Granada0.0090280See
CHNChina Harbin Manchu0.0090172See
FJIFiji Viti Levu Island0.009057See
DEUGermany DKMS - China minority0.00861282See
INDIndia Lucknow1.70.0080123See
INDIndia Northeast Mech0.008063See
STPSao Tome Island Forro0.008066See
USAUSA African American pop 70.0080193See
CHLChile Mapuche0.007766See
BOLBolivia Quechua0.007269See
FINFinland pop20.0070150See
GTMGuatemala Mayan0.0070132See
RUSRussia Transbaikal Territory Buryats1.00.0070150See
RUSRussia Siberia Ulchi0.007073See
USAUSA African American Bethesda1.40.0070187See
USAUSA Southern California Mestizo1.40.007073See
ZWEZimbabwe Harare Shona0.0070230See
BRABrazil South Caucasian0.006973See
USAUSA Asian pop 20.00651772See
BOLBolivia La Paz Aymaras0.006087See
IDNIndonesia Nusa Tenggara Islands0.006049See
ZAFSouth Africa Worcester1.00.0060159See
USAUSA NMDP African American pop 20.0058416581See
USAUSA African American pop 40.00562411See
USAUSA Philippines0.0050105See
TUNTunisia Gabes Arab0.005096See
THAThailand Kamphaeng Phet0.005097See
RWARwanda Kigali Hutu and Tutsi0.0050281See
RUSRussia Tuva pop 20.0050169See
MNGMongolia Khalkha0.0050200See
INDIndia Uttar Pradesh0.0050202See
INDIndia Northeast Vaish0.0050198See
CHNChina pop11.00.0050103See
CHNChina Jiangsu Han0.00503238See
INDIndia Tamil Nadu0.00472492See
IRLIreland South0.80.0040250See
CHNChina Yunnan Province Naxi0.0040118See
CHNChina Hong Kong and Singapore0.0040135See
ISRIsrael Ethiopian Jews0.0040122See
CHNChina Jiangsu Province Han0.0035334See
RUSRussia Belgorod region0.70.0033153See
CHNChina Marrow Donor Registry0.0030600See
BRABrazil Puyanawa0.70.0030150See
CHNChina Beijing Shijiazhuang Tianjian Han0.0030618See
INDIndia Northeast Sunni0.0030188See
INDIndia Northeast Kayastha0.0030190See
INDIndia Northeast Mathur0.0030155See
CHNChina Hubei Han0.60.00293732See
USAUSA NMDP Filipino0.002850614See
RUSRussia Bashkortostan, Tatars0.50.0026192See
MYSMalaysia Peninsular Chinese0.50.0026194See
USAUSA NMDP Chinese0.002599672See
CHNChina Zhejiang Han pop 20.0024833See
KORSouth Korea pop 10.0020324See
TWNTaiwan Han Chinese0.0020504See
LKASri Lanka Colombo0.40.0020714See
USAUSA South Dakota Lakota Sioux0.0020302See
USAUSA Alaska Yupik0.0020252See
RUSRussia Nizhny Novgorod, Russians0.40.00201510See
HKGHong Kong Chinese BMDR0.00187595See
HKGHong Kong Chinese cord blood registry0.00183892See
MYSMalaysia Peninsular Malay0.30.0016951See
USAUSA NMDP Vietnamese0.001243540See
USAUSA NMDP Japanese0.001224582See
TWNTaiwan pop 20.0010364See
USAUSA NMDP Korean0.000777584See
GMBGambia pop 30.10.0005939See
ISRIsrael Ethiopia Jews0.00015928See
INDIndia Northeast Rastogi0.0000196See
INDIndia Northeast Shia0.0000190See
IDNIndonesia Moluccan Islands0.000024See
INDIndia Northeast Rajbanshi0.000098See
COLColombia Bogota and Medellin Mestizo0.000065See
CHNChina Urumqi Kazak0.000042See
CHNChina Harbin Korean0.0000201See
CZECzech Republic Romani0.00.000034See
BRABrazil Kaingang0.0000235See
ARGArgentina Chubut Tehuelche0.000023See
ARGArgentina Salta Wichi0.000024See
ARGArgentina Gran Chaco Mataco Wichi0.000049See
ARGArgentina Gran Chaco Western Toba Pilaga0.000019See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
BRABrazil Southeast Mixed Race0.00.000042See
BRABrazil Central Plateau Xavante0.000074See
BRABrazil East Amazon0.000041See
CANCanada British Columbia Athabaskan0.000062See
CANCanada British Columbia Penutian0.000026See
CAFCentral African Republic Aka Pygmy0.00.000093See
THAThailand North Dai Lue0.000096See
TUNTunisia Jerba Berber0.000055See
RUSRussia Siberia Negidal0.000035See
RUSRussia Siberia Khabarovsk Evenki0.000025See
RUSRussia Tuva pop30.000044See
RUSRussia Tuva Todja0.000022See
RUSRussia Siberia Irkutsk Tofalar0.000043See
RUSRussia Siberia Kushun Buryat0.000025See
STPSao Tome Island Angolar0.000032See
JPNJapan Hyogo Osaka and Nagano0.0000195See
KORSouth Korea pop 20.00.0000207See
MNGMongolia Oold0.0000104See
MNGMongolia Tsaatan0.0000144See
MNGMongolia Khalkha pop 20.0000202See
PNGPapua New Guinea Lowland0.000047See
PNGPapua New Guinea Lowland Wosera0.000079See
PNGPapua New Guinea Highland0.000094See
PRYParaguay Aché0.000087See
PRYParaguay Lengua0.000017See
PERPeru Quechua0.000044See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
NCLNew Caledonia0.000065See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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