Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.



Allele reported 202 time(s) and present in 167 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MLIMali Bandiagara0.2830138See
BFABurkina Faso Fulani0.214049See
BFABurkina Faso Mossi0.179053See
GHAGhana Ga-Adangbe32.10.1718131See
SENSenegal Niokholo Mandenka0.1680165See
ESPSpain Gipuzkoa Basque0.1660100See
BFABurkina Faso Rimaibe0.160047See
GNQEquatorial Guinea Bioko Island Bubi0.1050100See
ZMBZambia Lusaka0.100044See
ESPSpain Catalonia Girona0.098088See
USAUSA African American pop 40.09792411See
USAUSA NMDP African American pop 20.0969416581See
USAUSA NMDP Caribean Black0.096633328See
USAUSA NMDP African0.091428557See
KENKenya, Nyanza Province, Luo tribe17.00.0900100See
USAUSA NMDP Caribean Hispanic0.0850115374See
USAUSA NMDP Caribean Indian0.083014339See
USAUSA African American0.0830252See
ESPSpain Sevilla15.50.0827278See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,15.20.08074335See
ZWEZimbabwe Harare Shona0.0800230See
ESPSpain Majorca and Minorca0.071090See
MARMorocco Atlantic Coast Chaouya0.071098See
MARMorocco Settat Chaouya14.20.071098See
ESPSpain Andalusia0.067099See
USAUSA San Antonio Caucasian0.0667222See
DEUGermany DKMS - Spain minority0.06571107See
ZAFSouth Africa Caucasians0.0640102See
USAUSA African American Bethesda11.70.0640187See
USAUSA Hispanic0.0620234See
CMRCameroon Beti0.0600174See
CHESwitzerland Luzern0.05391553See
CHESwitzerland Lausanne0.0536993See
COLColombia Bogotá Cord Blood10.00.05131463See
FRAFrance Southeast10.00.0510130See
ESPSpain Andalusia Romani0.051099See
USAUSA Hispanic pop 20.05051999See
USAUSA NMDP Hispanic South or Central American0.0503146714See
SDNSudan Mixed10.00.0500200See
NIRIreland Northern9.90.05001000See
UGAUganda Kampala0.0490161See
UGAUganda Kampala pop 20.0490175See
COLColombia North Wiwa El Encanto0.048152See
NICNicaragua Managua9.20.0476339See
USAUSA NMDP Mexican or Chicano0.0473261235See
KENKenya Luo0.0450265See
CMRCameroon Bamileke0.045077See
KENKenya Nandi0.0440240See
USAUSA Caucasian pop 40.04391070See
TZATanzania Maasai8.10.0438336See
ITAItaly North0.0430277See
USAUSA San Diego8.30.0430496See
USAUSA San Francisco Caucasian0.0420220See
MEXMexico Mexico City Mestizo population0.0420143See
ZAFSouth Africa Worcester8.00.0410159See
GBRUnited Kingdom pop 38.10.0410604See
DEUGermany DKMS - Portugal minority0.04041176See
DEUGermany DKMS - France minority0.04001406See
IRLIreland South8.00.0400250See
USAUSA South Texas Hispanic0.0390194See
CMRCameroon Sawa0.038013See
CHESwitzerland Sion0.0371832See
PRTPortugal Center pop 20.0370562See
ITAItaly pop 50.0370975See
INDIndia Mumbai Maratha0.037091See
USAUSA NMDP American Indian South or Central America0.03605926See
FRAFrance Corsica Island0.0350100See
CHESwitzerland Bern0.03493545See
CHESwitzerland Geneva pop 20.03441267See
ITAItaly North pop 36.70.034097See
USAUSA NMDP European Caucasian0.03381242890See
CHESwitzerland Graubunden0.0331759See
CHESwitzerland Basel0.03281888See
MARMorocco Nador Metalsa pop 20.032073See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0320146See
DEUGermany DKMS - United Kingdom minority0.03161043See
USAUSA Philadelphia Caucasian6.10.0310141See
CHESwitzerland Zurich0.03034875See
CHESwitzerland St Gallen0.03022113See
ITAItaly Bergamo5.90.0300101See
INDIndia West Coast Parsi0.030050See
USAUSA Caucasian Bethesda5.30.0300307See
CHESwitzerland Aargau-Solothurn0.02981838See
CHESwitzerland Lugano0.02961169See
ENGEngland London Ashkenazi Jews0.0290500See
USAUSA NMDP North American Amerindian0.028135791See
USAUSA Eastern European0.0280558See
CHESwitzerland Geneva0.027080See
PRTAzores Terceira Island0.0270130See
PAKPakistan Karachi Parsi0.027091See
NLDNetherlands Leiden0.02701305See
MEXMexico Mexico City Mestizo pop 20.0256234See
CHLChile Santiago Mixed5.00.025370See
DEUGermany DKMS - Italy minority0.02521159See
USAUSA Caucasian pop 20.0250265See
BRABrazil Mixed0.0240108See
NLDNetherlands UMCU4.70.023464See
DEUGermany pop 80.022539689See
DEUGermany DKMS - Austria minority0.02211698See
DEUGermany DKMS - German donors0.02203456066See
DEUGermany pop 60.02198862See
PRTPortugal Azores Terceira Island4.40.0219130See
USAUSA North American Native0.0210187See
ISRIsrael Arab Druze0.0200101See
AUSAustralia New South Wales Caucasian0.0200134See
DEUGermany DKMS - Netherlands minority0.01971374See
ITAItaly North Pavia0.019081See
GEOGeorgia Tibilisi0.0190109See
CZECzech Republic NMDR0.01805099See
ITAItaly South0.0180141See
USAUSA NMDP Alaska Native or Aleut0.01801376See
GEOGeorgia Tibilisi Kurd0.017031See
USAUSA NMDP Middle Eastern or North Coast of Africa0.016970890See
DEUGermany DKMS - Romania minority0.01541234See
USAUSA NMDP Hawaiian or other Pacific Islander0.015111499See
CAFCentral African Republic Mbenzele Pygmy3.00.015136See
PAKPakistan Mixed Sindhi0.0150101See
POLPoland DKMS0.013720653See
BRABrazil Puyanawa2.70.0130150See
SAUSaudi Arabia Guraiat and Hail2.40.0120213See
MEXMexico Chiapas Lacandon Mayans0.0115218See
COLColombia North Chimila Amerindians0.010647See
IRNIran Baloch0.0100100See
ZAFSouth Africa Natal Tamil0.010051See
TWNTaiwan Siraya2.00.010051See
AREUnited Arab Emirates Abu Dhabi0.009652See
INDIndia New Delhi0.009071See
DEUGermany DKMS - Croatia minority0.00852057See
CHNChina Beijing0.008067See
PAKPakistan Baloch0.008066See
MEXMexico Tixcacaltuyub Maya0.007567See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00731028See
RUSRussia Transbaikal Territory Buryats1.00.0070150See
RUSRussia Karelia0.00611075See
DEUGermany Essen1.20.0060174See
INDIndia Delhi pop 21.20.006090See
DEUGermany DKMS - Greece minority0.00581894See
FRAFrance West1.00.0050100See
CHNChina Qinghai Province Hui0.0050110See
LBNLebanon Mixed0.005097See
RUSRussia Bering Island Aleuts0.0048104See
IRNIran Tehran0.0040120See
TURTurkey pop 50.0040142See
USAUSA South Dakota Lakota Sioux0.0030302See
JORJordan Amman0.0030146See
USAUSA NMDP Filipino0.002750614See
DEUGermany DKMS - Turkey minority0.00264856See
MYSMalaysia Peninsular Chinese0.50.0026194See
GRCGreece pop 60.0021242See
USAUSA Alaska Yupik0.0020252See
MYSMalaysia Peninsular Indian0.40.0018271See
USAUSA NMDP Japanese0.001624582See
USAUSA Asian pop 20.00171772See
USAUSA NMDP Southeast Asian0.001327978See
CHNChina North Han pop 20.0009567See
USAUSA NMDP South Asian Indian0.0007185391See
HKGHong Kong Chinese BMDR0.00077595See
USAUSA NMDP Vietnamese0.000343540See
USAUSA NMDP Chinese0.000299672See
USAUSA NMDP Korean0.000177584See
USAUSA Asian0.0000358See
ITAItaly Sardinia pop30.0000100See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
CHNChina Guangzhou0.0000102See
CHNChina South Han pop 20.00001098See
CHNChina Tibet Region Tibetan0.0000158See
CHNChina North Han0.0000105See
CHNChina Inner Mongolia Region0.0000102See
CMRCameroon Baka Pygmy0.000010See
AUSAustralia Yuendumu Aborigine0.0000191See
BRABrazil Vale do Ribeira Quilombos0.10.0000144See
CMRCameroon Bakola Pygmy0.00.000050See
KORSouth Korea pop 30.0000485See
RUSRussia Arkhangelsk Pomor0.000063See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PHLPhilippines Ivatan0.00.000050See
SCOScotland Orkney0.00.000099See
TWNTaiwan Thao0.00.000030See
TTOTrinidad South Asian0.000087See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See

See also higher resolution data of this allele

Allele  Number of Populations 
 C*16:01:01 35 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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