Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 225 time(s) and present in 184 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CMRCameroon Baka Pygmy0.200010See
CMRCameroon Sawa0.154013See
CAFCentral African Republic Mbenzele Pygmy22.00.116836See
BGRBulgaria Romani0.091013See
ISRIsrael Iraq Jews0.086313270See
SDNSudan Mixed12.00.0680200See
ISRIsrael Druze0.05885914See
ISRIsrael Morocco Jews0.056536718See
ISRIsrael Arab Druze0.0550101See
LBYLibya Cyrenaica0.0550118See
CHNChina Uyghur HIV negative0.053019See
TZATanzania Maasai9.90.0524336See
IRNIran Tabriz Azeris0.051597See
BOLBolivia/Chile Aymara NA-DHS_13 (G)10.00.050020See
ISRIsrael Arab pop 20.048812301See
CMRCameroon Bakola Pygmy8.00.040850See
ISRIsrael Iran Jews0.04078153See
ISRIsrael Ethiopia Jews0.04025928See
SAUSaudi Arabia Guraiat and Hail7.80.0390213See
ISRIsrael YemenJews0.036615542See
SAUSaudi Arabia pop 6 (G)0.034428927See
USAUSA Spain Ancestry0.0320279See
KENKenya Nandi0.0310240See
ISRIsrael Bukhara Jews0.03082317See
ISRIsrael Tunisia Jews0.02839070See
USAUSA NMDP Middle Eastern or North Coast of Africa0.026970890See
CRICosta Rica Cabecar NA-DHS_9 (G)5.30.026319See
GTMGuatemala Kaqchikel NA-DHS_8 (G)5.30.026319See
GRCGreece pop 84.80.024183See
ZAFSouth Africa Worcester4.00.0220159See
ISRIsrael USA Jews0.02136058See
MARMorocco Settat Chaouya4.20.021098See
MARMorocco Atlantic Coast Chaouya0.021098See
ISRIsrael Ashkenazi Jews pop 30.02094625See
ESPSpain Andalusia Romani0.020099See
BFABurkina Faso Mossi0.019053See
CHESwitzerland Aargau-Solothurn0.01881838See
ISRIsrael Libya Jews0.01843739See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0180146See
IRNIran Yazd0.017956See
ISRIsrael Poland Jews0.017413871See
DEUGermany DKMS - Turkey minority0.01644856See
CPVCape Verde Southeastern Islands0.016062See
CRICosta Rica Central Valley Mestizo (G)3.20.0160221See
FRAFrance Southeast3.10.0160130See
MKDMacedonia pop 40.0160216See
NLDNetherlands UMCU3.10.015664See
ISRIsrael Argentina Jews0.01524307See
USAUSA Philadelphia Caucasian2.20.0150141See
GRCGreece pop 60.0142242See
CZECzech Republic0.0140106See
ISRIsrael USSR Jews0.013745681See
ISRIsrael Georgia Jews0.01354471See
SGPSingapore SGVP. Indian INS0.013086See
DEUGermany DKMS - Italy minority0.01291159See
SAUSaudi Arabia pop 52.50.0127158See
USAUSA Hispanic pop 20.01251999See
ISRIsrael Kavkazi Jews0.01212840See
DEUGermany DKMS - Greece minority0.01211894See
ESPSpain Andalusia0.012099See
MEXMexico Mestizo2.40.012041See
USAUSA Mexican American Mestizo0.0120553See
ZMBZambia Lusaka0.011044See
UGAUganda Kampala pop 20.0110175See
USAUSA Hispanic0.0110234See
KENKenya Luo0.0110265See
BFABurkina Faso Rimaibe0.011047See
BRABrazil Belo Horizonte Caucasian2.10.011095See
CHESwitzerland Zurich0.01084875See
MEXMexico Mexico City Mestizo pop 20.0107234See
NICNicaragua Managua1.80.0105339See
USAUSA NMDP Hispanic South or Central American0.0101146714See
USAUSA NMDP Caribean Indian0.010014339See
KENKenya, Nyanza Province, Luo tribe2.00.0100100See
ITAItaly pop 50.0100975See
JORJordan Amman0.0100146See
USAUSA NMDP Mexican or Chicano0.0099261235See
CHESwitzerland Basel0.00991888See
USAUSA NMDP Caribean Hispanic0.0099115374See
USAUSA Italy Ancestry0.0090273See
UGAUganda Kampala0.0090161See
GEOGeorgia Tibilisi0.0090109See
CRICosta Rica Guanacaste Mestizo (G)1.80.0090110See
PRTPortugal Azores Terceira Island1.80.0088130See
USAUSA NMDP African0.008428557See
IRNIran Saqqez-Baneh Kurds0.008360See
IRNIran Kurd pop 20.008060See
INDIndia New Delhi0.008071See
PRTAzores Terceira Island0.0080130See
USAUSA North American Native0.0080187See
USAUSA South Texas Hispanic0.0080194See
USAUSA Caucasian pop 20.0080265See
USAUSA NMDP Hawaiian or other Pacific Islander0.007611499See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,1.50.00744335See
DEUGermany DKMS - Romania minority0.00731234See
CHNChina Jiangsu Province Han0.0070334See
NICNicaragua Mestizo (G)1.40.0070155See
MEXMexico Mexico City Mestizo population0.0070143See
COLColombia Bogotá Cord Blood1.40.00681463See
DEUGermany DKMS - Portugal minority0.00681176See
CHESwitzerland Geneva pop 20.00671267See
MEXMexico Mexico City Tlalpan1.20.0061330See
RUSRussia Karelia0.00611075See
ARGArgentina Rosario Toba1.20.006086See
DEUGermany pop 80.005439689See
DEUGermany DKMS - Austria minority0.00531698See
CRICosta Rica African -Caribbean (G)1.00.0050102See
DEUGermany DKMS - Netherlands minority0.00511374See
CMRCameroon Yaounde0.005092See
CHNChina Inner Mongolia Region0.0050102See
CHNChina Qinghai Province Hui0.0050110See
NLDNetherlands Leiden0.00501305See
MEXMexico Guadalajara Mestizo pop 20.0050103See
USAUSA Eastern European0.0050558See
USAUSA African American pop 80.0050605See
USAUSA African American pop 30.0050564See
ZAFSouth Africa Natal Zulu1.00.0050100See
ZAFSouth Africa Caucasians0.0050102See
USAUSA San Francisco Caucasian0.0050220See
USAUSA African American pop 40.00502411See
RUSRussia Bering Island Aleuts0.0048104See
POLPoland DKMS0.004720653See
USAUSA Caucasian pop 40.00471070See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00441028See
USAUSA NMDP European Caucasian0.00431242890See
DEUGermany DKMS - German donors0.00423456066See
CZECzech Republic NMDR0.00415099See
DEUGermany DKMS - Spain minority0.00411107See
IRLIreland South0.80.0040250See
USAUSA NMDP American Indian South or Central America0.00405926See
ZWEZimbabwe Harare Shona0.0040230See
USAUSA European American pop 20.00401245See
USAUSA Caucasian Bethesda0.80.0040307See
SWESweden Southern Sami0.0040130See
DEUGermany pop 60.00378862See
USAUSA NMDP Southeast Asian0.003627978See
USAUSA NMDP South Asian Indian0.0035185391See
DEUGermany DKMS - United Kingdom minority0.00341043See
HRVCroatia pop 40.00314000See
IDNIndonesia Sundanese and Javanese0.0030201See
NIRIreland Northern0.60.00301000See
FRAFrance Grenoble, Nantes and Rennes0.00306094See
CHESwitzerland Luzern0.00301553See
CHESwitzerland Lugano0.00301169See
USAUSA NMDP African American pop 20.0030416581See
DEUGermany DKMS - France minority0.00281406See
USAUSA NMDP North American Amerindian0.002835791See
USAUSA NMDP Caribean Black0.002633328See
CHESwitzerland Lausanne0.0026993See
CHESwitzerland Bern0.00263545See
DEUGermany DKMS - Croatia minority0.00222057See
MYSMalaysia Peninsular Malay0.40.0021951See
LKASri Lanka Colombo0.40.0020714See
ENGEngland North West0.30.0020298See
CHNChina Beijing Shijiazhuang Tianjian Han0.0020618See
USAUSA NMDP Alaska Native or Aleut0.00201376See
INDIndia Tamil Nadu0.00162492See
DEUGermany DKMS - China minority0.00161282See
USAUSA Asian pop 20.00141772See
TWNTaiwan pop 20.0010364See
CHNChina Jiangsu Han0.00103238See
USAUSA NMDP Filipino0.001050614See
USAUSA NMDP Vietnamese0.000943540See
CHNChina Hubei Han0.10.00073732See
CHESwitzerland Graubunden0.0007759See
USAUSA NMDP Japanese0.000424582See
USAUSA NMDP Chinese0.000499672See
HKGHong Kong Chinese BMDR0.00027595See
HKGHong Kong Chinese cord blood registry0.00013892See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000146682See
USAUSA NMDP Korean0.000177584See
USAUSA Asian0.0000358See
USAUSA African American Bethesda0.00.0000187See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
USAUSA African American0.0000252See
USAUSA Alaska Yupik0.0000252See
SGPSingapore SGVP Malay MAS0.000089See
USAUSA San Antonio Caucasian0.0000222See
IDNIndonesia Java pop 20.000036See
MARMorocco Nador Metalsa pop 20.000073See
KORSouth Korea pop 30.0000485See
MLIMali Bandiagara0.0000138See
PHLPhilippines Ivatan0.00.000050See
SGPSingapore Chinese0.00.0000149See
SGPSingapore SGVP Chinese CHS0.000096See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
BFABurkina Faso Fulani0.000049See
CMRCameroon Bamileke0.000077See
CMRCameroon Beti0.0000174See
CPVCape Verde Northwestern Islands0.000062See
CHNChina Tibet Region Tibetan0.0000158See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHNChina North Han0.0000105See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
GNBGuinea Bissau0.000065See
HKGHong Kong Chinese0.00.0000569See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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