Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 245 time(s) and present in 208 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
UGAUganda Kampala pop 20.1090175See
ZWEZimbabwe Harare Shona0.0930230See
CIVIvory Coast Adiopodoume Akan0.091044See
KENKenya, Nyanza Province, Luo tribe16.00.0800100See
MARMorocco Settat Chaouya13.60.068098See
MARMorocco Atlantic Coast Chaouya0.068098See
TZATanzania Maasai12.30.0674336See
TUNTunisia Ghannouch0.067082See
KENKenya Luo0.0660265See
CMRCameroon Bamileke0.065077See
CMRCameroon Beti0.0640174See
MLIMali Bandiagara0.0620138See
GNBGuinea Bissau0.062065See
KENKenya Nandi0.0570240See
BFABurkina Faso Mossi0.057053See
USAUSA African American0.0540252See
USAUSA African American pop 80.0530605See
CMRCameroon Baka Pygmy0.050010See
PRTPortugal Center0.050050See
USAUSA NMDP African American pop 20.0495416581See
USAUSA African American pop 30.0470564See
ZMBZambia Lusaka0.046044See
USAUSA African American pop 40.04502411See
USAUSA NMDP African0.044528557See
USAUSA NMDP Caribean Black0.044033328See
MARMorocco Nador Metalsa pop 20.043073See
CMRCameroon Sawa0.038013See
TUNTunisia Gabes0.036895See
CUBCuba Mixed Race7.10.036042See
ZAFSouth Africa Natal Zulu7.00.0350100See
CRICosta Rica African -Caribbean (G)6.80.0340102See
CMRCameroon Yaounde0.033092See
GHAGhana Accre Asutuare Akan0.0330429See
SDNSudan Mixed6.00.0330200See
COLColombia North Chimila Amerindians0.031947See
ZAFSouth African Mixed ancestry6.00.030050See
SDNSudan Central Shaigiya Mixed5.60.028436See
TUNTunisia pop 30.0280104See
UGAUganda Kampala0.0280161See
ZAFSouth Africa Worcester6.00.0280159See
SENSenegal Niokholo Mandenka0.0270165See
USAUSA NMDP Caribean Hispanic0.0263115374See
USAUSA NMDP Caribean Indian0.026014339See
BRABrazil Belo Horizonte Caucasian5.30.026095See
INDIndia Jalpaiguri Toto5.00.025340See
ITAItaly North Pavia0.025081See
NLDNetherlands UMCU4.70.023464See
CRICosta Rica Central Valley Mestizo (G)4.60.0230221See
CRICosta Rica Guanacaste Mestizo (G)4.60.0230110See
CUBCuba Caucasian4.30.021070See
USAUSA African American Bethesda4.20.0210187See
USAUSA South Texas Hispanic0.0210194See
ESPSpain Andalusia Romani0.020099See
GHAGhana Ga-Adangbe3.80.0191131See
NICNicaragua Mestizo (G)3.80.0190155See
USAUSA Mexican American Mestizo0.0180553See
USAUSA NMDP Hispanic South or Central American0.0171146714See
STPSao Tome Island Angolar0.016032See
FRAFrance Southeast3.10.0160130See
CRICosta Rica Amerindians (G)3.20.0160125See
CPVCape Verde Southeastern Islands0.016062See
ISRIsrael Arab pop 20.015412301See
USAUSA Hispanic pop 20.01531999See
CAFCentral African Republic Mbenzele Pygmy3.00.015136See
IRNIran Baloch0.0150100See
MEXMexico Guadalajara Mestizo pop 20.0150103See
USAUSA NMDP Mexican or Chicano0.0145261235See
COLColombia Bogotá Cord Blood2.90.01441463See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,2.80.01424335See
DEUGermany DKMS - Spain minority0.01401107See
PRTPortugal Azores Terceira Island2.60.0132130See
DEUGermany DKMS - Portugal minority0.01231176See
ESPSpain Andalusia0.012099See
NICNicaragua Managua2.40.0120339See
PRTAzores Terceira Island0.0120130See
MEXMexico Chihuahua Chihuahua City Pop 22.30.011488See
BFABurkina Faso Rimaibe0.011047See
PRTPortugal North0.011046See
PRTPortugal South0.010049See
BFABurkina Faso Fulani0.010049See
AREUnited Arab Emirates pop 21.90.0100373See
CHLChile Santiago Mixed2.00.010070See
CMRCameroon Bakola Pygmy2.00.010050See
DEUGermany DKMS - Italy minority0.00991159See
LBYLibya Cyrenaica0.0090118See
PRTAzores Central Islands0.009059See
STPSao Tome Island Forro0.008066See
USAUSA NMDP American Indian South or Central America0.00805926See
NLDNetherlands Leiden0.00801305See
CPVCape Verde Northwestern Islands0.008062See
ISRIsrael Tunisia Jews0.00789070See
MEXMexico Mexico City Tlalpan1.50.0076330See
USAUSA NMDP Middle Eastern or North Coast of Africa0.007170890See
DEUGermany DKMS - France minority0.00711406See
BRABrazil Puyanawa1.30.0070150See
NIRIreland Northern1.30.00701000See
JORJordan Amman0.0070146See
SAUSaudi Arabia Guraiat and Hail1.50.0070213See
USAUSA San Francisco Caucasian0.0070220See
CHESwitzerland Sion0.0065832See
MEXMexico Mexico City Mestizo pop 20.0064234See
USAUSA NMDP North American Amerindian0.006335791See
ISRIsrael Iran Jews0.00628153See
ITAItaly Bergamo1.00.0060101See
GRCGreece pop 81.20.006083See
CHESwitzerland Lugano0.00601169See
ESPSpain Catalonia Girona0.006088See
USAUSA European American pop 20.00601245See
USAUSA Caucasian1.20.006061655See
USAUSA NMDP European Caucasian0.00591242890See
DEUGermany DKMS - United Kingdom minority0.00581043See
DEUGermany DKMS - Netherlands minority0.00551374See
USAUSA NMDP Hawaiian or other Pacific Islander0.005311499See
ISRIsrael Morocco Jews0.005136718See
ISRIsrael Arab Druze0.0050101See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0050146See
NZLNew Zealand Maori with Admixed History1.00.0050105See
ENGEngland North West1.00.0050298See
CHNChina Qinghai Province Hui0.0050110See
USAUSA San Diego1.00.0050496See
SCOScotland Orkney1.00.005099See
SGPSingapore SGVP Chinese CHS0.005096See
USAUSA Spain Ancestry0.0050279See
USAUSA Eastern European0.0050558See
USAUSA North American Native0.0050187See
ZAFSouth Africa Caucasians0.0050102See
ISRIsrael Libya Jews0.00493739See
RUSRussia Bering Island Aleuts0.0048104See
ISRIsrael Iraq Jews0.004713270See
DEUGermany DKMS - Austria minority0.00471698See
DEUGermany pop 80.004539689See
CHESwitzerland Lausanne0.0045993See
DEUGermany DKMS - German donors0.00443456066See
DEUGermany pop 60.00448862See
DEUGermany DKMS - Romania minority0.00411234See
CHNChina South Han0.0040284See
CHNChina Canton Han0.0040264See
AUSAustralia New South Wales Caucasian0.0040134See
USAUSA Italy Ancestry0.0040273See
USAUSA Caucasian pop 20.0040265See
USAUSA Philadelphia Caucasian0.70.0040141See
RUSRussia Karelia0.00371075See
CHNChina Jiangsu Province Han0.0035334See
MEXMexico Mexico City Mestizo population0.0035143See
CHESwitzerland Geneva pop 20.00331267See
POLPoland DKMS0.003320653See
ISRIsrael Argentina Jews0.00314307See
GTMGuatemala Mayan0.0030132See
ITAItaly pop 50.0030975See
USAUSA San Antonio Caucasian0.0030222See
USAUSA NMDP Alaska Native or Aleut0.00301376See
USAUSA Caucasian pop 40.00281070See
CHESwitzerland Basel0.00281888See
ISRIsrael Druze0.00285914See
MYSMalaysia Peninsular Malay0.40.0026951See
MYSMalaysia Peninsular Chinese0.50.0026194See
CZECzech Republic NMDR0.00255099See
GRCGreece pop 60.0024242See
DEUGermany DKMS - Croatia minority0.00222057See
USAUSA Asian pop 20.00231772See
HKGHong Kong Chinese cord blood registry0.00223892See
USAUSA NMDP Chinese0.002099672See
USAUSA South Dakota Lakota Sioux0.0020302See
IRLIreland South0.40.0020250See
MKDMacedonia pop 40.0020216See
DEUGermany DKMS - Turkey minority0.00204856See
CHESwitzerland Graubunden0.0020759See
CHNChina Jiangsu Han0.00203238See
CHESwitzerland Bern0.00193545See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00201028See
HRVCroatia pop 40.00194000See
HKGHong Kong Chinese BMDR0.00157595See
ISRIsrael Ethiopia Jews0.00145928See
ISRIsrael USA Jews0.00136058See
CHESwitzerland Zurich0.00124875See
USAUSA NMDP Southeast Asian0.001127978See
ISRIsrael Ashkenazi Jews pop 30.00114625See
USAUSA NMDP Filipino0.001050614See
HKGHong Kong Chinese0.20.0010569See
ISRIsrael USSR Jews0.001045681See
ISRIsrael Poland Jews0.000913871See
CHNChina Hubei Han0.20.00093732See
USAUSA NMDP South Asian Indian0.0009185391See
DEUGermany DKMS - China minority0.00081282See
DEUGermany DKMS - Greece minority0.00081894See
ISRIsrael Bukhara Jews0.00062317See
INDIndia Tamil Nadu0.00042492See
USAUSA NMDP Japanese0.000424582See
ISRIsrael Kavkazi Jews0.00042840See
ISRIsrael YemenJews0.000315542See
ISRIsrael Georgia Jews0.00024471See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000246682See
USAUSA NMDP Vietnamese0.000143540See
JPNJapan pop 160.000118604See
KORSouth Korea pop 100.00014128See
USAUSA NMDP Korean0.000177584See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
USAUSA Alaska Yupik0.0000252See
PRTAzores Oriental Islands0.000043See
SGPSingapore Chinese0.00.0000149See
SGPSingapore SGVP. Indian INS0.000086See
SGPSingapore SGVP Malay MAS0.000089See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
USAUSA Hispanic0.0000234See
USAUSA Asian0.0000358See
USAUSA Caucasian Bethesda0.00.0000307See
KORSouth Korea pop 30.0000485See
MEXMexico Mestizo0.00.000041See
PHLPhilippines Ivatan0.00.000050See
ESPSpain Gipuzkoa Basque0.0000100See
CZECzech Republic0.0000106See
CHNChina Tibet Region Tibetan0.0000158See
CHNChina Inner Mongolia Region0.0000102See
CHNChina North Han0.0000105See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Aargau-Solothurn0.00001838See
BRABrazil Vale do Ribeira Quilombos0.10.0000144See
AUSAustralia Yuendumu Aborigine0.0000191See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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