Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 251 time(s) and present in 221 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ISRIsrael Ethiopia Jews0.18675928See
ARMArmenia combined Regions0.0950100See
PRTPortugal North0.087046See
ISRIsrael Georgia Jews0.06814471See
ESPSpain Gipuzkoa Basque0.0610100See
CUBCuba Mixed Race11.90.060042See
ISRIsrael Druze0.05625914See
CMRCameroon Yaounde0.054092See
UGAUganda Kampala pop 20.0540175See
MARMorocco Nador Metalsa pop 20.051073See
ISRIsrael Iraq Jews0.050913270See
IRNIran Saqqez-Baneh Kurds0.050060See
IRNIran Kurd pop 20.050060See
CUBCuba Caucasian10.00.050070See
ISRIsrael Arab pop 20.049512301See
STPSao Tome Island Angolar0.047032See
ISRIsrael Morocco Jews0.046536718See
KENKenya Nandi0.0460240See
ISRIsrael YemenJews0.043915542See
ITAItaly pop 50.0430975See
USAUSA South Texas Hispanic0.0430194See
SDNSudan Mixed8.50.0430200See
PRTPortugal South0.041049See
DEUGermany DKMS - Italy minority0.04061159See
TZATanzania Maasai8.10.0404336See
TUNTunisia pop 30.0400104See
CPVCape Verde Southeastern Islands0.040062See
CANCanada Chipewyan NA-DHS_2 (G)8.00.040025See
PRTPortugal Azores Terceira Island7.00.0395130See
INDIndia Jalpaiguri Toto7.50.038240See
PRTAzores Oriental Islands0.038043See
USAUSA NMDP African0.038028557See
USAUSA NMDP Middle Eastern or North Coast of Africa0.037770890See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,7.30.03714335See
SENSenegal Niokholo Mandenka0.0370165See
UGAUganda Kampala0.0370161See
IRNIran Tabriz Azeris0.036197See
PRTAzores Central Islands0.036059See
PRTAzores Terceira Island0.0350130See
ESPSpain Andalusia Romani0.035099See
ESPSpain Andalusia0.035099See
DEUGermany DKMS - Turkey minority0.03434856See
ESPSpain Catalonia Girona0.034088See
GEOGeorgia Tibilisi Kurd0.034031See
MARMorocco Atlantic Coast Chaouya0.034098See
USAUSA African American0.0340252See
MARMorocco Settat Chaouya6.80.034098See
ITAItaly North pop 36.70.033097See
GRCGreece pop 60.0330242See
CHESwitzerland Luzern0.03271553See
CMRCameroon Beti0.0320174See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0320146See
RUSRussia Tundra Nentsi NA-DHS_1 (G)6.30.031316See
GNBGuinea Bissau0.031065See
DEUGermany DKMS - Portugal minority0.03061176See
DEUGermany DKMS - Spain minority0.03031107See
GRCGreece pop 86.00.030183See
CHESwitzerland Geneva pop 20.03001267See
USAUSA Eastern European0.0300558See
USAUSA Philadelphia Caucasian5.90.0300141See
USAUSA African American pop 40.02822411See
COLColombia Bogotá Cord Blood5.30.02801463See
USAUSA NMDP African American pop 20.0279416581See
CANCanada Cree NA-DHS_3 (G)5.60.027818See
FRAFrance Southeast5.40.0270130See
ISRIsrael Bukhara Jews0.02702317See
DEUGermany DKMS - Bosnia and Herzegovina minority0.02681028See
USAUSA NMDP Caribean Hispanic0.0264115374See
USAUSA NMDP Caribean Black0.026333328See
TUNTunisia Gabes0.026395See
CHNChina Uyghur HIV negative0.026019See
USAUSA NMDP Hispanic South or Central American0.0257146714See
MLIMali Bandiagara0.0250138See
CHLChile Huilliche NA-DHS_14 (G)5.00.025020See
ISRIsrael Arab Druze0.0250101See
TUNTunisia Ghannouch0.024082See
JORJordan Amman0.0240146See
MEXMexico Guadalajara Mestizo pop 20.0240103See
CPVCape Verde Northwestern Islands0.024062See
USAUSA Hispanic pop 20.02351999See
CHESwitzerland Lausanne0.0234993See
IRNIran Gorgan0.023064See
FRAFrance French Bone Marrow Donor Registry0.023042623See
GEOGeorgia Tibilisi0.0230109See
ISRIsrael Tunisia Jews0.02299070See
USAUSA NMDP Mexican or Chicano0.0225261235See
DEUGermany DKMS - Greece minority0.02241894See
USAUSA San Diego4.20.0220496See
USAUSA NMDP Caribean Indian0.022014339See
USAUSA African American pop 80.0220605See
SAUSaudi Arabia Guraiat and Hail4.40.0220213See
CHESwitzerland Bern0.02123545See
CHESwitzerland Lugano0.02101169See
BRABrazil Belo Horizonte Caucasian4.20.021095See
MEXMexico Mexico City Mestizo population0.0210143See
USAUSA African American Bethesda4.20.0210187See
DEUGermany DKMS - France minority0.02031406See
CHLChile Santiago Mixed4.00.020270See
USAUSA African American pop 30.0200564See
HRVCroatia pop 40.01934000See
MEXMexico Mexico City Mestizo pop 20.0192234See
GHAGhana Ga-Adangbe3.80.0191131See
GEOGeorgia Svaneti Region Svan0.019080See
MKDMacedonia pop 40.0190216See
CMRCameroon Bamileke0.019077See
CZECzech Republic0.0190106See
USAUSA Caucasian Bethesda3.10.0190307See
USAUSA Hispanic0.0190234See
DEUGermany DKMS - Croatia minority0.01822057See
MYSMalaysia Kelantan3.60.018028See
USAUSA European American pop 20.01801245See
USAUSA Mexican American Mestizo0.0180553See
MEXMexico Veracruz Xalapa3.60.017984See
ISRIsrael Iran Jews0.01788153See
CZECzech Republic NMDR0.01775099See
ISRIsrael Kavkazi Jews0.01742840See
USAUSA NMDP American Indian South or Central America0.01705926See
DEUGermany pop 80.016339689See
DEUGermany DKMS - Romania minority0.01621234See
CHESwitzerland Aargau-Solothurn0.01611838See
GHAGhana Accre Asutuare Akan0.0160429See
USAUSA San Francisco Caucasian0.0160220See
USAUSA NMDP European Caucasian0.01581242890See
USAUSA Caucasian pop 40.01581070See
DEUGermany DKMS - Austria minority0.01531698See
ISRIsrael Poland Jews0.015113871See
NICNicaragua Managua3.00.0151339See
ISRIsrael USSR Jews0.014945681See
USAUSA NMDP North American Amerindian0.014535791See
RUSRussia Karelia0.01451075See
CHESwitzerland Zurich0.01444875See
BRABrazil Mixed0.0140108See
MEXMexico Mexico City Tlalpan2.70.0136330See
USAUSA North American Native0.0130187See
DEUGermany DKMS - United Kingdom minority0.01291043See
DEUGermany DKMS - German donors0.01293456066See
ISRIsrael Argentina Jews0.01294307See
POLPoland DKMS0.012920653See
DEUGermany pop 60.01278862See
CHESwitzerland Graubunden0.0122759See
ITAItaly North Pavia0.012081See
MEXMexico Mestizo2.40.012041See
CHESwitzerland St Gallen0.01182113See
ISRIsrael USA Jews0.01116058See
ISRIsrael Libya Jews0.01113739See
ISRIsrael Ashkenazi Jews pop 30.01104625See
ITAItaly Bergamo1.90.0110101See
SDNSudan South Nuba2.20.011046See
USAUSA NMDP Alaska Native or Aleut0.01101376See
ZMBZambia Lusaka0.011044See
ZAFSouth Africa Natal Zulu2.00.0100100See
SRBSerbia pop 22.00.0100102See
PRTPortugal Center0.010050See
NIRIreland Northern1.90.01001000See
KENKenya, Nyanza Province, Luo tribe2.00.0100100See
INDIndia Andhra Pradesh Golla0.0100111See
CHNChina North Han0.0100105See
DEUGermany DKMS - Netherlands minority0.00981374See
AREUnited Arab Emirates Abu Dhabi0.009652See
BRABrazil Terena1.70.009060See
NLDNetherlands Leiden0.00901305See
USAUSA San Antonio Caucasian0.0090222See
ZWEZimbabwe Harare Shona0.0090230See
ZAFSouth Africa Worcester2.00.0090159See
INDIndia Tamil Nadu0.00842492See
CHESwitzerland Basel0.00841888See
AUSAustralia New South Wales Caucasian0.0080134See
IRLIreland South1.60.0080250See
STPSao Tome Island Forro0.008066See
GTMGuatemala Mayan0.0070132See
ENGEngland North West1.30.0070298See
MEXMexico Chiapas Lacandon Mayans0.0069218See
CHESwitzerland Sion0.0065832See
USAUSA NMDP South Asian Indian0.0061185391See
USAUSA NMDP Southeast Asian0.006127978See
USAUSA Caucasian pop 20.0060265See
LKASri Lanka Colombo1.30.0060714See
MEXMexico Chihuahua Chihuahua City Pop 21.10.005788See
IRNIran Baloch0.0050100See
CHNChina Guangzhou Han0.0050106See
CHNChina Inner Mongolia Region0.0050102See
CHNChina Qinghai Province Hui0.0050110See
ZAFSouth Africa Caucasians0.0050102See
SGPSingapore SGVP Chinese CHS0.005096See
USAUSA NMDP Hawaiian or other Pacific Islander0.004911499See
SWESweden Southern Sami0.0040130See
KENKenya Luo0.0040265See
CHNChina Jiangsu Province Han0.0035334See
BRABrazil Puyanawa0.70.0030150See
CHNChina Beijing Shijiazhuang Tianjian Han0.0020618See
CHNChina Marrow Donor Registry0.0020600See
USAUSA Alaska Yupik0.0020252See
USAUSA NMDP Filipino0.002050614See
MYSMalaysia Peninsular Indian0.40.0018271See
MYSMalaysia Peninsular Malay0.20.0011951See
USAUSA Asian pop 20.00111772See
CHNChina Jiangsu Han0.00103238See
CHNChina Hubei Han0.10.00073732See
USAUSA NMDP Chinese0.000699672See
KORSouth Korea pop 100.00054128See
USAUSA NMDP Japanese0.000524582See
HKGHong Kong Chinese BMDR0.00037595See
USAUSA NMDP Korean0.000377584See
DEUGermany DKMS - China minority0.00041282See
HKGHong Kong Chinese cord blood registry0.00033892See
USAUSA NMDP Vietnamese0.000243540See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000146682See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
PHLPhilippines Ivatan0.00.000050See
SGPSingapore SGVP. Indian INS0.000086See
SGPSingapore SGVP Malay MAS0.000089See
SGPSingapore Chinese0.00.0000149See
USAUSA Asian0.0000358See
HKGHong Kong Chinese0.00.0000569See
KORSouth Korea pop 30.0000485See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
CHNChina Tibet Region Tibetan0.0000158See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
AUSAustralia Yuendumu Aborigine0.0000191See
BFABurkina Faso Fulani0.000049See
BFABurkina Faso Mossi0.000053See
BFABurkina Faso Rimaibe0.000047See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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