Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 268 time(s) and present in 231 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
SAUSaudi Arabia Guraiat and Hail30.20.1730213See
AREUnited Arab Emirates Abu Dhabi0.144252See
SDNSudan East Rashaida25.90.139127See
MARMorocco Settat Chaouya22.00.110098See
MARMorocco Atlantic Coast Chaouya0.110098See
TUNTunisia Gabes0.105295See
IRNIran Yazd0.098256See
ISRIsrael Arab Druze0.0850101See
CHNChina Uyghur HIV negative0.079019See
MARMorocco Nador Metalsa pop 20.073073See
ISRIsrael Druze0.06865914See
TUNTunisia pop 30.0630104See
IRNIran Saqqez-Baneh Kurds0.058360See
IRNIran Kurd pop 20.058060See
ISRIsrael Tunisia Jews0.05639070See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0550146See
ISRIsrael Arab pop 20.053212301See
PRTAzores Terceira Island0.0510130See
PRTPortugal Azores Terceira Island9.60.0482130See
ISRIsrael YemenJews0.046715542See
ARMArmenia combined Regions0.0450100See
IRNIran Tabriz Azeris0.041297See
ISRIsrael Iran Jews0.04008153See
INDIndia Delhi pop 27.70.038090See
GEOGeorgia Svaneti Region Svan0.038080See
ITAItaly Bergamo6.90.0360101See
COLColombia Inga NA-DHS_11 (G)7.10.035716See
GEOGeorgia Tibilisi Kurd0.034031See
ITAItaly North pop 36.70.033097See
BRABrazil Belo Horizonte Caucasian6.30.032095See
ISRIsrael Morocco Jews0.031136718See
ITAItaly North Pavia0.031081See
PRTPortugal South0.031049See
DEUGermany DKMS - Turkey minority0.03034856See
USAUSA NMDP Middle Eastern or North Coast of Africa0.029770890See
ISRIsrael Libya Jews0.02873739See
GEOGeorgia Tibilisi0.0280109See
ISRIsrael Poland Jews0.026413871See
PRTAzores Oriental Islands0.026043See
ISRIsrael Iraq Jews0.025613270See
ISRIsrael Bukhara Jews0.02552317See
ESPSpain Andalusia Romani0.025099See
SDNSudan Mixed5.00.0250200See
ISRIsrael Georgia Jews0.02404471See
ISRIsrael Argentina Jews0.02404307See
ESPSpain Andalusia0.024099See
CHESwitzerland Lugano0.02401169See
CZECzech Republic0.0240106See
SRBSerbia pop 24.90.0240102See
USAUSA Hispanic0.0240234See
ISRIsrael USA Jews0.02396058See
BOLBolivia/Peru Quechua NA-DHS_12 (G)4.80.023821See
ISRIsrael Kavkazi Jews0.02382840See
ISRIsrael Ashkenazi Jews pop 30.02304625See
GHAGhana Ga-Adangbe4.60.0229131See
ESPSpain Majorca and Minorca0.022090See
ITAItaly pop 50.0220975See
CUBCuba Caucasian4.30.021070See
USAUSA South Texas Hispanic0.0210194See
CHESwitzerland Luzern0.02091553See
USAUSA NMDP Caribean Hispanic0.0207115374See
ISRIsrael Ethiopia Jews0.02065928See
ISRIsrael USSR Jews0.020245681See
DEUGermany DKMS - Italy minority0.02031159See
CHESwitzerland Aargau-Solothurn0.02021838See
BFABurkina Faso Fulani0.020049See
CHNChina Inner Mongolia Region0.0200102See
USAUSA Italy Ancestry0.0200273See
USAUSA NMDP Caribean Indian0.020014339See
DEUGermany DKMS - Portugal minority0.02001176See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,3.90.01974335See
INDIndia North pop 20.019072See
CHNChina North Han0.0190105See
SGPSingapore SGVP. Indian INS0.019086See
COLColombia Bogotá Cord Blood3.70.01881463See
CHESwitzerland Lausanne0.0182993See
CHNChina Qinghai Province Hui0.0180110See
PRTAzores Central Islands0.018059See
DEUGermany DKMS - Spain minority0.01761107See
USAUSA NMDP South Asian Indian0.0172185391See
RUSRussia Tuva pop 20.0170169See
MEXMexico Chihuahua Chihuahua City Pop 23.40.017088See
ENGEngland North West3.40.0170298See
ESPSpain Catalonia Girona0.017088See
JORJordan Amman0.0170146See
MYSMalaysia Peninsular Indian3.30.0166271See
CHESwitzerland Graubunden0.0163759See
CPVCape Verde Southeastern Islands0.016062See
IRNIran Gorgan0.016064See
SENSenegal Niokholo Mandenka0.0160165See
USAUSA African American pop 80.0160605See
DEUGermany DKMS - Greece minority0.01561894See
USAUSA NMDP Southeast Asian0.015227978See
CHLChile Santiago Mixed3.00.015170See
CHNChina Sichuan HIV negative0.015034See
INDIndia New Delhi0.015071See
GNBGuinea Bissau0.015065See
MEXMexico Guadalajara Mestizo pop 20.0150103See
USAUSA NMDP Hispanic South or Central American0.0150146714See
HRVCroatia pop 40.01464000See
DEUGermany DKMS - Romania minority0.01461234See
USAUSA Hispanic pop 20.01451999See
CHESwitzerland Zurich0.01444875See
DEUGermany DKMS - Austria minority0.01411698See
BRABrazil Mixed0.0140108See
USAUSA Spain Ancestry0.0140279See
USAUSA Mexican American Mestizo0.0140553See
CHESwitzerland Geneva pop 20.01331267See
USAUSA NMDP Mexican or Chicano0.0133261235See
DEUGermany pop 80.013239689See
FRAFrance French Bone Marrow Donor Registry0.013142623See
USAUSA Eastern European0.0130558See
DEUGermany DKMS - France minority0.01281406See
INDIndia Tamil Nadu0.01242492See
GRCGreece pop 82.40.012183See
MEXMexico Mexico City Tlalpan2.40.0121330See
FRAFrance Southeast2.30.0120130See
CUBCuba Mixed Race2.40.012042See
CHESwitzerland St Gallen0.01182113See
USAUSA NMDP African0.011728557See
DEUGermany DKMS - Bosnia and Herzegovina minority0.01121028See
BFABurkina Faso Rimaibe0.011047See
DEUGermany DKMS - United Kingdom minority0.01101043See
USAUSA African American Bethesda2.10.0110187See
USAUSA Philadelphia Caucasian2.20.0110141See
MLIMali Bandiagara0.0110138See
PRTPortugal North0.011046See
USAUSA NMDP European Caucasian0.01051242890See
DEUGermany DKMS - German donors0.01053456066See
CZECzech Republic NMDR0.01055099See
CHESwitzerland Basel0.01051888See
POLPoland DKMS0.010220653See
MEXMexico Mixtec0.010097See
NZLNew Zealand Maori with Admixed History1.90.0100105See
NIRIreland Northern1.90.01001000See
MEXMexico Oaxaca Jamiltepec Mixtec0.010096See
USAUSA San Diego1.90.0100496See
ZAFSouth Africa Natal Tamil0.010051See
DEUGermany DKMS - Croatia minority0.01002057See
IRLIreland South2.00.0100250See
ITAItaly Sardinia pop30.0100100See
DEUGermany pop 60.00998862See
RUSRussia Bering Island Aleuts0.0096104See
GRCGreece pop 60.0094242See
USAUSA African American pop 40.00932411See
USAUSA NMDP American Indian South or Central America0.00905926See
USAUSA Caucasian pop 20.0090265See
USAUSA European American pop 20.00901245See
GHAGhana Accre Asutuare Akan0.0090429See
CHESwitzerland Bern0.00903545See
USAUSA NMDP African American pop 20.0089416581See
USAUSA NMDP Caribean Black0.008833328See
MEXMexico Mexico City Mestizo pop 20.0085234See
USAUSA NMDP Alaska Native or Aleut0.00801376See
AUSAustralia New South Wales Caucasian0.0080134See
CPVCape Verde Northwestern Islands0.008062See
USAUSA NMDP North American Amerindian0.007935791See
NLDNetherlands UMCU1.60.007864See
NICNicaragua Managua1.50.0075339See
USAUSA Asian pop 20.00741772See
ZWEZimbabwe Harare Shona0.0070230See
MEXMexico Mexico City Mestizo population0.0070143See
MKDMacedonia pop 40.0070216See
AUSAustralia Groote Eylandt Aborigine0.007075See
DEUGermany DKMS - China minority0.00661282See
USAUSA Caucasian pop 40.00651070See
USAUSA African American pop 30.0060564See
USAUSA African American0.0060252See
ZAFSouth Africa Worcester1.00.0060159See
NLDNetherlands Leiden0.00601305See
CMRCameroon Bamileke0.006077See
CHNChina Beijing Shijiazhuang Tianjian Han0.0060618See
CHNChina Tibet Region Tibetan0.0060158See
CHNChina Jiangsu Han0.00603238See
DEUGermany DKMS - Netherlands minority0.00551374See
CHNChina Jiangsu Province Han0.0052334See
CHNChina Guizhou Province Bouyei0.0050109See
CHNChina Yunnan Province Jinuo0.0050109See
CHNChina Guangzhou0.0050102See
CMRCameroon Yaounde0.005092See
CHNChina Marrow Donor Registry0.0050600See
ESPSpain Gipuzkoa Basque0.0050100See
KENKenya, Nyanza Province, Luo tribe1.00.0050100See
ZAFSouth Africa Caucasians0.0050102See
USAUSA North American Native0.0050187See
RUSRussia Karelia0.00471075See
THAThailand Northeast0.004066See
USAUSA Alaska Yupik0.0040252See
CHNChina Southwest Dai0.0040124See
CHNChina Hubei Han0.80.00383732See
HKGHong Kong Chinese BMDR0.00347595See
HKGHong Kong Chinese cord blood registry0.00333892See
USAUSA NMDP Hawaiian or other Pacific Islander0.003311499See
THAThailand Northeast pop 20.0030400See
UGAUganda Kampala pop 20.0030175See
LKASri Lanka Colombo0.60.0030714See
CMRCameroon Beti0.0030174See
USAUSA NMDP Chinese0.002799672See
MYSMalaysia Peninsular Malay0.50.0026951See
MYSMalaysia Peninsular Chinese0.50.0026194See
CHESwitzerland Sion0.0025832See
USAUSA NMDP Vietnamese0.002143540See
USAUSA San Francisco Caucasian0.0020220See
TWNTaiwan pop 20.0020364See
CHNChina South Han0.0020284See
CHNChina Canton Han0.0020264See
KENKenya Luo0.0020265See
KORSouth Korea pop 100.00174128See
USAUSA NMDP Korean0.001477584See
USAUSA NMDP Filipino0.001350614See
TWNTaiwan Tzu Chi Cord Blood Bank0.0010710See
USAUSA Asian0.0010358See
KORSouth Korea pop 30.0010485See
HKGHong Kong Chinese0.20.0010569See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000946682See
USAUSA NMDP Japanese0.000524582See
JPNJapan pop 160.000218604See
KENKenya Nandi0.0000240See
FRAFrance Corsica Island0.0000100See
CHNChina Guizhou Province Miao pop 20.000085See
CHNChina Yunnan Province Wa0.0000119See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
CHNChina Guizhou Province Shui0.0000153See
CHNChina Beijing0.000067See
AUSAustralia Yuendumu Aborigine0.0000191See
BFABurkina Faso Mossi0.000053See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
USAUSA Caucasian Bethesda0.00.0000307See
ZAFSouth Africa Natal Zulu0.00.0000100See
ZMBZambia Lusaka0.000044See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
UGAUganda Kampala0.0000161See
USAUSA San Antonio Caucasian0.0000222See
SGPSingapore Chinese0.00.0000149See
SGPSingapore SGVP Chinese CHS0.000096See
SGPSingapore SGVP Malay MAS0.000089See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
MEXMexico Mestizo0.00.000041See
PHLPhilippines Ivatan0.00.000050See
PRTPortugal Center0.000050See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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