Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 204 time(s) and present in 185 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
IRNIran Kurd pop 20.050060See
IRNIran Saqqez-Baneh Kurds0.050060See
ISRIsrael Bukhara Jews0.04752317See
ISRIsrael Georgia Jews0.04654471See
LKASri Lanka Colombo8.70.0450714See
INDIndia New Delhi0.038071See
IRNIran Tabriz Azeris0.036197See
SGPSingapore Chinese Han0.035094See
ESPSpain Andalusia Romani0.035099See
GEOGeorgia Tibilisi Kurd0.034031See
INDIndia Delhi pop 26.60.033090See
CHESwitzerland St Gallen0.03152113See
FRAFrance Southeast6.20.0310130See
ISRIsrael Arab Druze0.0300101See
INDIndia North pop 20.029072See
ISRIsrael Druze0.02905914See
DEUGermany DKMS - Turkey minority0.02864856See
DEUGermany DKMS - Greece minority0.02851894See
CHESwitzerland Basel0.02811888See
GEOGeorgia Tibilisi0.0280109See
RUSRussia Tuva pop 20.0280169See
CHESwitzerland Luzern0.02761553See
CHNChina Uyghur HIV negative0.026019See
PRTAzores Oriental Islands0.026043See
USAUSA Philadelphia Caucasian5.20.0260141See
SGPSingapore Thai0.0250100See
SDNSudan Mixed0.50.0250200See
IRNIran Baloch0.0250100See
GEOGeorgia Svaneti Region Svan0.025080See
ISRIsrael Ashkenazi Jews pop 30.02434625See
MEXMexico Mestizo4.90.024041See
ESPSpain Andalusia0.024099See
SRBSerbia pop 24.90.0240102See
ISRIsrael Kavkazi Jews0.02392840See
ISRIsrael Argentina Jews0.02334307See
ISRIsrael Tunisia Jews0.02339070See
NIRIreland Northern4.60.02301000See
ENGEngland North West4.70.0230298See
ISRIsrael Iran Jews0.02298153See
ISRIsrael USA Jews0.02256058See
ISRIsrael Arab pop 20.022412301See
MYSMalaysia Peninsular Indian3.70.0221271See
USAUSA NMDP Middle Eastern or North Coast of Africa0.021970890See
ISRIsrael Morocco Jews0.021536718See
ISRIsrael Poland Jews0.021213871See
USAUSA San Antonio Caucasian0.0211222See
USAUSA Caucasian pop 20.0210265See
DEUGermany DKMS - Italy minority0.02081159See
DEUGermany DKMS - Romania minority0.02071234See
USAUSA NMDP South Asian Indian0.0203185391See
CHESwitzerland Zurich0.02004875See
ARMArmenia combined Regions0.0200100See
IRLIreland South4.00.0200250See
ISRIsrael USSR Jews0.019545681See
NLDNetherlands Leiden0.01901305See
CHNChina Canton Han0.0190264See
USAUSA European American pop 20.01901245See
USAUSA NMDP European Caucasian0.01861242890See
CHESwitzerland Graubunden0.0183759See
PRTAzores Central Islands0.018059See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0180146See
INDIndia Tamil Nadu0.01732492See
TUNTunisia pop 30.0170104See
DEUGermany pop 60.01638862See
CHESwitzerland Aargau-Solothurn0.01611838See
DEUGermany DKMS - United Kingdom minority0.01611043See
IRNIran Gorgan0.016064See
USAUSA Eastern European0.0160558See
USAUSA Caucasian Bethesda3.20.0160307See
DEUGermany DKMS - Austria minority0.01591698See
FRAFrance French Bone Marrow Donor Registry0.015842623See
USAUSA NMDP Southeast Asian0.015527978See
DEUGermany pop 80.015439689See
DEUGermany DKMS - German donors0.01533456066See
CHESwitzerland Lugano0.01501169See
ZAFSouth Africa Caucasians0.0150102See
DEUGermany DKMS - France minority0.01491406See
DEUGermany DKMS - Bosnia and Herzegovina minority0.01461028See
DEUGermany DKMS - Netherlands minority0.01461374See
DEUGermany DKMS - Spain minority0.01451107See
USAUSA NMDP North American Amerindian0.014335791See
CHESwitzerland Bern0.01413545See
CHNChina Yunnan Province Jinuo0.0140109See
INDIndia Andhra Pradesh Golla0.0140111See
USAUSA NMDP American Indian South or Central America0.01405926See
CHESwitzerland Geneva pop 20.01331267See
CHNChina Tibet Region Tibetan0.0130158See
ITAItaly pop 50.0130975See
SGPSingapore SGVP. Indian INS0.013086See
HRVCroatia pop 40.01254000See
DEUGermany DKMS - Croatia minority0.01242057See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,2.50.01234335See
DEUGermany DKMS - Portugal minority0.01231176See
USAUSA Caucasian pop 40.01211070See
SWESweden Southern Sami0.0120130See
UGAUganda Kampala0.0120161See
CZECzech Republic NMDR0.01195099See
ISRIsrael Iraq Jews0.011913270See
ISRIsrael Libya Jews0.01123739See
PRTPortugal North0.011046See
BRABrazil Belo Horizonte Caucasian2.10.011095See
AUSAustralia New South Wales Caucasian0.0110134See
USAUSA NMDP Alaska Native or Aleut0.01101376See
USAUSA North American Native0.0110187See
USAUSA Hispanic pop 20.01051999See
CHESwitzerland Lausanne0.0104993See
POLPoland DKMS0.010320653See
PRTPortugal Center0.010050See
SGPSingapore Riau Malay0.0100132See
MEXMexico Guadalajara Mestizo pop 20.0100103See
USAUSA South Dakota Lakota Sioux0.0100302See
RUSRussia Bering Island Aleuts0.0096104See
AREUnited Arab Emirates Abu Dhabi0.009652See
RUSRussia Karelia0.00941075See
MEXMexico Mexico City Tlalpan1.80.0091330See
USAUSA NMDP Hispanic South or Central American0.0091146714See
USAUSA NMDP Mexican or Chicano0.0090261235See
USAUSA Hispanic0.0090234See
USAUSA San Francisco Caucasian0.0090220See
IRNIran Yazd0.008956See
ISRIsrael YemenJews0.008815542See
USAUSA NMDP Caribean Hispanic0.0087115374See
USAUSA African American0.0080252See
USAUSA San Diego1.60.0080496See
CHNChina Beijing0.008067See
NLDNetherlands UMCU1.60.007864See
CHESwitzerland Sion0.0076832See
COLColombia Bogotá Cord Blood1.40.00721463See
CUBCuba Caucasian1.40.007070See
MARMorocco Atlantic Coast Chaouya0.007098See
MARMorocco Settat Chaouya1.40.007098See
JORJordan Amman0.0070146See
USAUSA NMDP Caribean Indian0.007014339See
SAUSaudi Arabia Guraiat and Hail1.50.0070213See
MEXMexico Mexico City Mestizo pop 20.0064234See
MYSMalaysia Peninsular Malay1.30.0063951See
NICNicaragua Managua1.20.0060339See
CHNChina Beijing Shijiazhuang Tianjian Han0.0060618See
GRCGreece pop 81.20.006083See
SGPSingapore SGVP Malay MAS0.006089See
USAUSA NMDP Hawaiian or other Pacific Islander0.005511499See
USAUSA Asian pop 20.00541772See
TUNTunisia Gabes0.005295See
USAUSA African American pop 80.0050605See
USAUSA African American Bethesda1.10.0050187See
CHNChina Inner Mongolia Region0.0050102See
CHNChina Guangxi Region Maonan0.0050108See
AUSAustralia Cape York Peninsula Aborigine0.0050103See
NZLNew Zealand Maori with Admixed History1.00.0050105See
PRTPortugal Azores Terceira Island0.90.0044130See
USAUSA African American pop 40.00422411See
USAUSA NMDP Caribean Black0.004033328See
USAUSA South Texas Hispanic0.0040194See
PRTAzores Terceira Island0.0040130See
USAUSA NMDP African American pop 20.0040416581See
USAUSA Asian0.0030358See
ZAFSouth Africa Worcester1.00.0030159See
SWESweden Northern Sami0.0030154See
AUSAustralia Yuendumu Aborigine0.0030191See
USAUSA NMDP African0.002828557See
CHNChina Marrow Donor Registry0.0020600See
USAUSA NMDP Filipino0.001150614See
USAUSA NMDP Japanese0.001024582See
CHNChina Jiangsu Han0.00103238See
USAUSA NMDP Vietnamese0.000843540See
USAUSA NMDP Chinese0.000899672See
USAUSA NMDP Korean0.000777584See
DEUGermany DKMS - China minority0.00081282See
KORSouth Korea pop 100.00074128See
HKGHong Kong Chinese cord blood registry0.00063892See
HKGHong Kong Chinese BMDR0.00067595See
CHNChina Hubei Han0.10.00053732See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000546682See
ISRIsrael Ethiopia Jews0.00025928See
KENKenya Nandi0.0000240See
KENKenya Luo0.0000265See
KORSouth Korea pop 30.0000485See
MLIMali Bandiagara0.0000138See
MARMorocco Nador Metalsa pop 20.000073See
SGPSingapore Chinese0.00.0000149See
PRTPortugal South0.000049See
CHNChina Guangzhou0.0000102See
CHNChina North Han0.0000105See
CHNChina Qinghai Province Hui0.0000110See
CHNChina Yunnan Province Wa0.0000119See
CUBCuba Mixed Race0.00.000042See
HKGHong Kong Chinese0.00.0000569See
INDIndia Mumbai Maratha0.000091See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
USAUSA Alaska Yupik0.0000252See
SGPSingapore SGVP Chinese CHS0.000096See
ZMBZambia Lusaka0.000044See
ZAFSouth Africa Natal Zulu0.00.0000100See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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