Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 241 time(s) and present in 238 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
VENVenezuela Sierra de Perija Yucpa0.714073See
TWNTaiwan Saisiat92.20.667051See
PNGPapua New Guinea East New Britain Rabaul0.571060See
MEXMexico Chiapas Lacandon Mayans0.3784218See
MEXMexico Oaxaca Mixtec0.3330103See
CHNChina Yunnan Province Lisu0.3290111See
TWNTaiwan Taroko56.40.318055See
CHNChina Yunnan Province Nu0.3070107See
VENVenezuela Perja Mountain Bari0.303055See
PNGPapua New Guinea Madang0.302065See
USAUSA NMDP Filipino0.289450614See
TWNTaiwan Atayal51.90.2880106See
MEXMexico Oaxaca Zapotec0.284090See
TWNTaiwan Tsou43.10.275051See
MEXMexico Oaxaca Mixe0.264055See
RUSRussia Arkhangelsk Pomor0.260063See
PAKPakistan Burusho0.255092See
CHNChina Yunnan Hani0.2530150See
USAUSA South Dakota Lakota Sioux0.2440302See
RUSRussia Nenet Mixed0.238055See
CHNChina Sichuan HIV negative0.235034See
USAUSA New Mexico Canoncito Navajo0.232042See
TWNTaiwan Hakka43.60.227055See
CHNChina Canton Han0.2100264See
CHNChina South Han0.2080284See
MEXMexico Mexico City Mestizo pop 20.2073234See
TWNTaiwan Minnan pop 137.30.2060102See
BRABrazil Terena34.00.202060See
TWNTaiwan pop 20.2010364See
TWNTaiwan Han Chinese0.2010504See
CHNChina Guangzhou0.1990102See
USAUSA Asian0.1950358See
USAUSA NMDP Chinese0.194499672See
SGPSingapore Thai0.1900100See
CHNChina Yunnan Bulang0.1900116See
CHNChina Guizhou Province Bouyei0.1860109See
CHNChina Guizhou Province Shui0.1860153See
NIRIreland Northern33.80.18601000See
HKGHong Kong Chinese BMDR0.18507595See
CHESwitzerland Geneva0.182080See
TWNTaiwan Bunun32.70.1780101See
CHNChina South Han pop 20.17761098See
USAUSA Arizona Gila River Amerindian0.1770492See
IRLIreland South33.20.1740250See
NLDNetherlands UMCU31.30.171964See
SGPSingapore Javaneses0.170051See
USAUSA Caucasian Bethesda31.10.1700307See
RUSRussia North Ossetian31.50.1693127See
NLDNetherlands Leiden0.16801305See
NZLNew Zealand Maori with Admixed History30.50.1670105See
CHNChina Marrow Donor Registry0.1670600See
PHLPhilippines Ivatan28.00.160050See
TWNTaiwan Rukai32.00.160050See
AUSAustralia New South Wales Caucasian0.1580134See
USAUSA San Antonio Caucasian0.1576222See
USAUSA South Texas Hispanic0.1560194See
ENGEngland North West27.90.1560298See
USAUSA NMDP Vietnamese0.155343540See
PAKPakistan Mixed Sindhi0.1550101See
GBRUnited Kingdom pop 328.60.1550604See
DEUGermany DKMS - China minority0.15441282See
RUSRussia Karelia0.15391075See
DEUGermany pop 60.15238862See
SAUSaudi Arabia Guraiat and Hail27.00.1520213See
USAUSA NMDP North American Amerindian0.151035791See
DEUGermany DKMS - United Kingdom minority0.15051043See
CMRCameroon Baka Pygmy0.150010See
TWNTaiwan Thao30.00.150030See
RUSRussia Bering Island Aleuts0.1490104See
NICNicaragua Managua26.40.1484339See
INDIndia Tamil Nadu Nadar0.148061See
CHNChina Guizhou Province Miao pop 20.147085See
VNMVietnam Hanoi Kinh pop 20.1470170See
MYSMalaysia Peninsular Chinese26.80.1469194See
DEUGermany DKMS - Netherlands minority0.14681374See
JPNJapan Central0.1460371See
USAUSA Asian pop 20.14561772See
USAUSA NMDP American Indian South or Central America0.14505926See
TWNTaiwan Pazeh27.30.145055See
USAUSA Philadelphia Caucasian27.60.1430141See
CHESwitzerland Graubunden0.1420759See
USAUSA NMDP European Caucasian0.14131242890See
USAUSA San Francisco Caucasian0.1410220See
RUSRussia Murmansk Saomi Mixed0.140070See
CHLChile Santiago Mixed26.00.139770See
USAUSA Hawaii Okinawa0.1380106See
USAUSA NMDP Mexican or Chicano0.1366261235See
CHNChina Beijing0.136067See
CHESwitzerland Bern0.13503545See
AREUnited Arab Emirates Abu Dhabi0.134652See
USAUSA Caucasian pop 40.13461070See
DEUGermany pop 80.134239689See
CHNChina Tibet Region Tibetan0.1330158See
CHNChina Qinghai Province Hui0.1320110See
DEUGermany DKMS - Austria minority0.13051698See
USAUSA NMDP Southeast Asian0.129427978See
CZECzech Republic NMDR0.12925099See
USAUSA North American Native0.1280187See
USAUSA NMDP Hawaiian or other Pacific Islander0.127311499See
JPNJapan pop 160.127118604See
JPNJapan pop 30.12701018See
CHNChina Inner Mongolia Region0.1270102See
INDIndia Tamil Nadu0.12662492See
USAUSA Caucasian pop 20.1250265See
PAKPakistan Brahui0.1250104See
PNGPapua New Guinea Wanigela Keapara0.125066See
CHESwitzerland Zurich0.12454875See
CHNChina North Han pop 20.1243567See
USAUSA Hispanic0.1240234See
CHESwitzerland Aargau-Solothurn0.12321838See
CZECzech Republic0.1230106See
JPNJapan pop 10.1230560See
DEUGermany DKMS - France minority0.12251406See
USAUSA NMDP Japanese0.121824582See
USAUSA NMDP Hispanic South or Central American0.1214146714See
CHNChina North Han0.1190105See
POLPoland DKMS0.118820653See
TWNTaiwan Paiwan19.60.118051See
CHESwitzerland Geneva pop 20.11621267See
CHNChina Wuhan22.50.1160121See
USAUSA Eastern European0.1160558See
CHESwitzerland St Gallen0.11522113See
CHESwitzerland Lausanne0.1151993See
CMRCameroon Sawa0.115013See
JPNJapan pop 50.1130117See
USAUSA Hispanic pop 20.11281999See
CHESwitzerland Luzern0.11071553See
TWNTaiwan Tao20.00.110050See
NZLNew Zealand Maori with Full Ancestry19.60.109046See
MYSMalaysia Peninsular Malay20.50.1088951See
TWNTaiwan Siraya19.60.108051See
USAUSA NMDP South Asian Indian0.1078185391See
CHESwitzerland Basel0.10731888See
TWNTaiwan Ami20.40.107098See
USAUSA San Diego20.20.1040496See
RUSRussia Transbaikal Territory Buryats19.00.1030150See
JPNJapan Kyoto and Osaka0.1030165See
CHNChina Southwest Dai0.1010124See
NCLNew Caledonia0.100065See
USAUSA NMDP Alaska Native or Aleut0.10001376See
INDIndia Delhi pop 214.80.099090See
CHESwitzerland Sion0.0978832See
COLColombia Bogotá Cord Blood18.40.09671463See
AUSAustralia Cape York Peninsula Aborigine0.0960103See
NZLNew Zealand Polynesians with Full Ancestry19.00.095021See
LKASri Lanka Colombo17.60.0950714See
PAKPakistan Mixed Pathan0.0950100See
DEUGermany DKMS - Spain minority0.09461107See
FRAFrance West18.00.0944100See
IRNIran Baloch0.0940100See
CHNChina Yunnan Province Han0.0940101See
ZAFSouth Africa Natal Tamil0.094051See
NZLNew Zealand Polynesians with Admixed History18.50.093027See
DEUGermany Essen16.70.0910174See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,17.20.09074335See
TWNTaiwan Puyuma18.00.090050See
USAUSA African American0.0890252See
INDIndia New Delhi0.089071See
DEUGermany DKMS - Romania minority0.08791234See
PAKPakistan Kalash0.087069See
COLColombia North Wiwa El Encanto0.086552See
INDIndia Mumbai Maratha0.086091See
RUSRussia Tuva pop 20.0860169See
KORSouth Korea pop 30.0830485See
USAUSA NMDP Korean0.082277584See
DEUGermany DKMS - Portugal minority0.08171176See
ASMAmerican Samoa0.080051See
BRABrazil Mixed0.0800108See
USAUSA African American Bethesda16.00.0800187See
CHNChina Uyghur HIV negative0.079019See
USAUSA NMDP Caribean Hispanic0.0761115374See
PRTPortugal Azores Terceira Island12.30.0746130See
ITAItaly South0.0740141See
DEUGermany DKMS - Turkey minority0.07394856See
USAUSA NMDP Middle Eastern or North Coast of Africa0.073970890See
DEUGermany DKMS - Italy minority0.07381159See
USAUSA NMDP Caribean Indian0.073014339See
USAUSA African American pop 30.0730564See
FRAFrance Southeast13.80.0720130See
DEUGermany DKMS - Croatia minority0.07172057See
CHESwitzerland Lugano0.07151169See
USAUSA NMDP African American pop 20.0713416581See
CMRCameroon Bamileke0.071077See
DEUGermany DKMS - Bosnia and Herzegovina minority0.07051028See
INDIndia West Bhil0.070050See
USAUSA African American pop 40.06972411See
ZAFSouth Africa Worcester14.00.0690159See
USAUSA NMDP African0.068328557See
AUSAustralia Yuendumu Aborigine0.0680191See
USAUSA NMDP Caribean Black0.066433328See
CMRCameroon Beti0.0660174See
GEOGeorgia Tibilisi0.0650109See
DEUGermany DKMS - Greece minority0.06491894See
ITAItaly pop 50.0630975See
UGAUganda Kampala0.0610161See
PAKPakistan Karachi Parsi0.060091See
TURTurkey pop 50.0600142See
ITAItaly North0.0600277See
ESPSpain Andalusia0.055099See
PNGPapua New Guinea Wosera Abelam0.0540131See
ESPSpain Sevilla10.10.0522278See
GRCGreece pop 60.0475242See
MLIMali Bandiagara0.0470138See
ZWEZimbabwe Harare Shona0.0460230See
PAKPakistan Baloch0.045066See
MEXMexico Chihuahua Tarahumara0.045044See
CHNChina Shanxi HIV negative0.045022See
BGRBulgaria Gipsy0.045013See
ZMBZambia Lusaka0.044044See
GHAGhana Ga-Adangbe8.40.0420131See
LBNLebanon Mixed0.041097See
ISRIsrael Arab Druze0.0400101See
KENKenya Luo0.0380265See
UGAUganda Kampala pop 20.0370175See
GRCGreece pop 87.20.036183See
SDNSudan Mixed7.00.0350200See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.035057See
GEOGeorgia Tibilisi Kurd0.034031See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0320146See
MARMorocco Nador Metalsa pop 20.032073See
CHNChina Han HIV negative0.031072See
CHNChina Henan HIV negative0.031016See
KENKenya, Nyanza Province, Luo tribe6.00.0300100See
INDIndia West Coast Parsi0.030050See
ENGEngland London Ashkenazi Jews0.0290500See
SENSenegal Niokholo Mandenka0.0210165See
PNGPapua New Guinea Karimui Plateau Pawaia0.019080See
ESPSpain Andalusia Gipsy0.019099See
USAUSA Alaska Yupik0.0150252See
KENKenya Nandi0.0080240See
POLPoland (G)0.00.000023595See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
INDIndia Khandesh Region Pawra0.000050See
BRABrazil Vale do Ribeira Quilombos0.10.0000144See
AUSAustralia Groote Eylandt Aborigine0.000075See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

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