Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 229 time(s) and present in 210 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CHNChina Han HIV negative0.156072See
CHNChina Henan HIV negative0.156016See
ESPSpain Andalusia Romani0.128099See
JPNJapan Kyoto and Osaka0.1210165See
PNGPapua New Guinea Wosera Abelam0.1160131See
JPNJapan pop 10.1140560See
JPNJapan pop 160.111818604See
JPNJapan pop 30.11001018See
TWNTaiwan Pazeh21.80.109055See
MYSMalaysia Peninsular Indian18.80.1052271See
JPNJapan Central0.1050371See
JPNJapan pop 50.1040117See
GEOGeorgia Tibilisi Kurd0.103031See
CHNChina Yunnan Hani0.1030150See
PAKPakistan Burusho0.102092See
PAKPakistan Mixed Sindhi0.1020101See
ITAItaly Sardinia pop30.1000100See
USAUSA NMDP Japanese0.100024582See
TWNTaiwan Siraya17.60.098051See
IRNIran Tehran0.0980120See
CHNChina Tibet Region Tibetan0.0920158See
BGRBulgaria Romani0.091013See
TWNTaiwan Puyuma18.00.090050See
SGPSingapore SGVP. Indian INS0.086086See
ZAFSouth Africa Natal Tamil0.083051See
INDIndia Tamil Nadu0.08292492See
USAUSA NMDP South Asian Indian0.0813185391See
TWNTaiwan Atayal15.10.0800106See
INDIndia Delhi pop 213.60.080090See
CHNChina Uyghur HIV negative0.079019See
LKASri Lanka Colombo15.10.0780714See
PAKPakistan Mixed Pathan0.0750100See
AREUnited Arab Emirates Abu Dhabi0.067352See
USAUSA NMDP Southeast Asian0.064327978See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0640146See
INDIndia New Delhi0.063071See
CHNChina Beijing0.061067See
PNGPapua New Guinea Madang0.060065See
TURTurkey pop 50.0560142See
CHNChina Inner Mongolia Region0.0540102See
CHNChina Guizhou Province Miao pop 20.053085See
PNGPapua New Guinea Wanigela Keapara0.049066See
GRCGreece pop 89.60.048283See
ITAItaly North0.0470277See
CHNChina Yunnan Province Han0.0450101See
USAUSA Asian pop 20.04491772See
CHNChina Southwest Dai0.0440124See
PAKPakistan Karachi Parsi0.044091See
NCLNew Caledonia0.044065See
GRCGreece pop 60.0434242See
CHNChina North Han0.0430105See
RUSRussia Tuva pop 20.0410169See
SGPSingapore Javaneses0.040051See
TWNTaiwan Han Chinese0.0400504See
PHLPhilippines Ivatan8.00.040050See
CHNChina Guizhou Province Shui0.0390153See
MYSMalaysia Peninsular Malay7.70.0389951See
RUSRussia Bering Island Aleuts0.0385104See
SGPSingapore Riau Malay0.0370132See
CHNChina Qinghai Province Hui0.0360110See
DEUGermany DKMS - China minority0.03391282See
USAUSA NMDP Middle Eastern or North Coast of Africa0.033070890See
SGPSingapore Thai0.0330100See
CHNChina North Han pop 20.0317567See
CHNChina Guangzhou0.0310102See
PNGPapua New Guinea Karimui Plateau Pawaia0.031080See
HKGHong Kong Chinese BMDR0.03077595See
USAUSA NMDP Chinese0.030799672See
CHNChina South Han pop 20.03011098See
CHNChina Yunnan Bulang0.0300116See
PAKPakistan Baloch0.030066See
TWNTaiwan Tao6.00.030050See
RUSRussia Arkhangelsk Pomor0.030063See
TWNTaiwan Minnan pop 15.90.0290102See
TWNTaiwan Tsou3.90.029051See
MYSMalaysia Peninsular Chinese5.70.0284194See
SDNSudan Mixed5.50.0280200See
USAUSA Asian0.0280358See
TWNTaiwan Hakka5.50.027055See
SGPSingapore SGVP Chinese CHS0.027096See
USAUSA NMDP Korean0.026877584See
DEUGermany DKMS - Turkey minority0.02564856See
KORSouth Korea pop 30.0250485See
ITAItaly South0.0250141See
CHNChina Hubei Han4.90.02453732See
USAUSA Hispanic0.0240234See
THAThailand Northeast pop 20.0240400See
RUSRussia Nenet Mixed0.024055See
USAUSA Hawaii Okinawa0.0240106See
DEUGermany DKMS - Greece minority0.02381894See
CHNChina Shanxi HIV negative0.023022See
CHNChina Marrow Donor Registry0.0230600See
USAUSA San Francisco Caucasian0.0230220See
ZAFSouth Africa Worcester4.00.0220159See
SGPSingapore SGVP Malay MAS0.022089See
USAUSA NMDP Caribean Indian0.022014339See
USAUSA South Texas Hispanic0.0210194See
TWNTaiwan pop 20.0210364See
VNMVietnam Hanoi Kinh pop 20.0210170See
RUSRussia Murmansk Saomi Mixed0.020070See
ESPSpain Gipuzkoa Basque0.0200100See
DEUGermany DKMS - Italy minority0.01911159See
USAUSA NMDP Vietnamese0.018943540See
ESPSpain Andalusia0.018099See
CHESwitzerland Zurich0.01784875See
CHESwitzerland Geneva pop 20.01701267See
CHNChina Canton Han0.0170264See
ITAItaly pop 50.0170975See
RUSRussia Transbaikal Territory Buryats3.00.0170150See
RUSRussia Karelia0.01681075See
USAUSA NMDP Hawaiian or other Pacific Islander0.016311499See
ESPSpain Sevilla3.20.0162278See
FRAFrance Corsica Island0.0160100See
CHNChina South Han0.0160284See
USAUSA San Diego2.90.0160496See
CHESwitzerland Aargau-Solothurn0.01551838See
CHESwitzerland St Gallen0.01522113See
CHLChile Santiago Mixed3.00.015170See
DEUGermany DKMS - Croatia minority0.01512057See
FRAFrance West3.00.0151100See
CHESwitzerland Basel0.01481888See
POLPoland DKMS0.014620653See
SAUSaudi Arabia Guraiat and Hail2.80.0140213See
CHNChina Guizhou Province Bouyei0.0140109See
PAKPakistan Kalash0.014069See
PAKPakistan Brahui0.0140104See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,2.60.01314335See
DEUGermany DKMS - Romania minority0.01301234See
USAUSA Hispanic pop 20.01301999See
DEUGermany DKMS - Austria minority0.01241698See
CHESwitzerland Lausanne0.0123993See
USAUSA NMDP Filipino0.012250614See
CZECzech Republic NMDR0.01225099See
DEUGermany DKMS - Spain minority0.01221107See
USAUSA San Antonio Caucasian0.0121222See
USAUSA NMDP American Indian South or Central America0.01205926See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.012057See
FRAFrance Southeast2.30.0120130See
ITAItaly North Pavia0.012081See
USAUSA NMDP Hispanic South or Central American0.0116146714See
USAUSA NMDP Caribean Hispanic0.0115115374See
USAUSA NMDP Mexican or Chicano0.0112261235See
ESPSpain Majorca and Minorca0.011090See
NZLNew Zealand Maori with Full Ancestry2.20.011046See
BFABurkina Faso Rimaibe0.011047See
DEUGermany pop 80.010839689See
DEUGermany DKMS - Bosnia and Herzegovina minority0.01021028See
ENGEngland North West2.00.0100298See
BFABurkina Faso Fulani0.010049See
ISRIsrael Arab Druze0.0100101See
TWNTaiwan Ami2.00.010098See
TWNTaiwan Saisiat2.00.010051See
ZAFSouth Africa Caucasians0.0100102See
USAUSA Philadelphia Caucasian2.00.0100141See
TWNTaiwan Taroko1.80.009055See
UGAUganda Kampala0.0090161See
USAUSA Caucasian pop 20.0090265See
GEOGeorgia Tibilisi0.0090109See
CHESwitzerland Luzern0.00901553See
DEUGermany DKMS - France minority0.00891406See
PRTPortugal Azores Terceira Island1.80.0088130See
USAUSA NMDP European Caucasian0.00871242890See
DEUGermany DKMS - Portugal minority0.00861176See
COLColombia Bogotá Cord Blood1.70.00851463See
DEUGermany DKMS - German donors0.00853456066See
USAUSA Eastern European0.0080558See
MARMorocco Nador Metalsa pop 20.008073See
MLIMali Bandiagara0.0080138See
IRNIran Gorgan0.007864See
DEUGermany pop 60.00758862See
CHESwitzerland Bern0.00743545See
CHESwitzerland Graubunden0.0073759See
JORJordan Amman0.0070146See
MEXMexico Mexico City Mestizo population0.0070143See
USAUSA NMDP Alaska Native or Aleut0.00701376See
PRTPortugal Center pop 20.0060562See
NLDNetherlands Leiden0.00601305See
ITAItaly Bergamo1.00.0060101See
IRLIreland South1.20.0060250See
CHESwitzerland Geneva0.006080See
ESPSpain Catalonia Girona0.006088See
DEUGermany DKMS - Netherlands minority0.00581374See
USAUSA Caucasian pop 40.00561070See
NICNicaragua Managua1.10.0055339See
NZLNew Zealand Maori with Admixed History1.00.0050105See
AUSAustralia New South Wales Caucasian0.0050134See
USAUSA North American Native0.0050187See
USAUSA NMDP North American Amerindian0.004835791See
USAUSA NMDP Caribean Black0.004433328See
MEXMexico Mexico City Mestizo pop 20.0043234See
GBRUnited Kingdom pop 30.80.0040604See
PRTAzores Terceira Island0.0040130See
RUSRussia North Ossetian0.80.0039127See
DEUGermany DKMS - United Kingdom minority0.00381043See
CHESwitzerland Lugano0.00371169See
BRABrazil Puyanawa0.70.0030150See
NIRIreland Northern0.60.00301000See
USAUSA NMDP African0.002828557See
MEXMexico Chiapas Lacandon Mayans0.0023218See
USAUSA African American0.0020252See
USAUSA African American pop 40.00152411See
USAUSA NMDP African American pop 20.0011416581See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
ZMBZambia Lusaka0.000044See
USAUSA Alaska Yupik0.0000252See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
SCOScotland Orkney0.00.000099See
SENSenegal Niokholo Mandenka0.0000165See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Thao0.00.000030See
KENKenya Nandi0.0000240See
KENKenya Luo0.0000265See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
ITAItaly North pop 30.00.000097See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
BFABurkina Faso Mossi0.000053See
AUSAustralia Yuendumu Aborigine0.0000191See
CHESwitzerland Sion0.0000832See
CZECzech Republic0.0000106See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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