Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 237 time(s) and present in 211 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ITAItaly North0.1500277See
PNGPapua New Guinea Wanigela Keapara0.132066See
GRCGreece pop 60.1302242See
DEUGermany DKMS - Croatia minority0.11892057See
DEUGermany DKMS - Bosnia and Herzegovina minority0.11721028See
PRTPortugal Azores Terceira Island22.80.1140130See
ITAItaly South0.1130141See
ITAItaly pop 50.1120975See
DEUGermany DKMS - Greece minority0.10731894See
PAKPakistan Burusho0.107092See
LBNLebanon Mixed0.106097See
CMRCameroon Bakola Pygmy20.00.105550See
SDNSudan Mixed21.00.1050200See
POLPoland DKMS0.103920653See
DEUGermany DKMS - Turkey minority0.10384856See
ESPSpain Andalusia Romani0.103099See
PRTAzores Terceira Island0.1010130See
ITAItaly North pop 320.00.100097See
ESPSpain Majorca and Minorca0.100090See
DEUGermany DKMS - Romania minority0.09871234See
ESPSpain Andalusia0.098099See
CHESwitzerland Lugano0.09511169See
IRNIran Gorgan0.093864See
RUSRussia Karelia0.09361075See
ESPSpain Sevilla17.60.0917278See
DEUGermany DKMS - Italy minority0.09141159See
USAUSA NMDP Middle Eastern or North Coast of Africa0.091170890See
CZECzech Republic NMDR0.08935099See
GEOGeorgia Tibilisi0.0890109See
PAKPakistan Karachi Parsi0.088091See
IRNIran Tehran0.0880120See
PAKPakistan Kalash0.087069See
RUSRussia Bering Island Aleuts0.0817104See
INDIndia Delhi pop 216.00.080090See
ESPSpain Catalonia Girona0.080088See
RUSRussia North Ossetian15.00.0787127See
CHESwitzerland Geneva pop 20.07801267See
ISRIsrael Arab Druze0.0750101See
CHESwitzerland Basel0.07451888See
CHNChina Yunnan Hani0.0730150See
FRAFrance Corsica Island0.0730100See
PAKPakistan Mixed Sindhi0.0730101See
GRCGreece pop 814.50.072383See
PAKPakistan Brahui0.0720104See
NZLNew Zealand Polynesians with Full Ancestry14.30.071021See
DEUGermany DKMS - Portugal minority0.07081176See
USAUSA Eastern European0.0700558See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,13.20.06864335See
SGPSingapore SGVP. Indian INS0.068086See
DEUGermany DKMS - Austria minority0.06581698See
ITAItaly Sardinia pop30.0650100See
USAUSA Caucasian Bethesda12.90.0640307See
ITAItaly Bergamo12.90.0640101See
DEUGermany pop 80.063239689See
CHESwitzerland Geneva0.063080See
INDIndia New Delhi0.063071See
DEUGermany DKMS - Spain minority0.06201107See
DEUGermany DKMS - France minority0.06171406See
USAUSA San Francisco Caucasian0.0580220See
DEUGermany DKMS - German donors0.05733456066See
NZLNew Zealand Polynesians with Admixed History11.10.056027See
CHESwitzerland Lausanne0.0554993See
FRAFrance Southeast10.80.0550130See
PRTPortugal Center pop 20.0530562See
CHNChina Uyghur HIV negative0.053019See
GEOGeorgia Tibilisi Kurd0.052031See
DEUGermany pop 60.05188862See
AUSAustralia Cape York Peninsula Aborigine0.0510103See
USAUSA Caucasian pop 20.0510265See
CHESwitzerland Luzern0.04931553See
USAUSA NMDP South Asian Indian0.0491185391See
USAUSA NMDP European Caucasian0.04861242890See
CHESwitzerland Zurich0.04824875See
CHESwitzerland St Gallen0.04812113See
AREUnited Arab Emirates Abu Dhabi0.048152See
SCOScotland Orkney9.60.048099See
CHESwitzerland Bern0.04793545See
CHESwitzerland Graubunden0.0477759See
USAUSA Hispanic0.0470234See
ENGEngland North West9.40.0470298See
USAUSA Philadelphia Caucasian9.20.0460141See
COLColombia Bogotá Cord Blood9.00.04551463See
PAKPakistan Baloch0.045066See
GNQEquatorial Guinea Bioko Island Bubi0.0450100See
BGRBulgaria Romani0.045013See
CHESwitzerland Sion0.0446832See
USAUSA NMDP Caribean Hispanic0.0438115374See
BFABurkina Faso Rimaibe0.043047See
USAUSA Caucasian pop 40.04301070See
DEUGermany DKMS - United Kingdom minority0.04281043See
USAUSA NMDP Hispanic South or Central American0.0415146714See
USAUSA NMDP Southeast Asian0.041327978See
CHESwitzerland Aargau-Solothurn0.04121838See
USAUSA Hispanic pop 20.04131999See
USAUSA NMDP Caribean Indian0.041014339See
CHLChile Santiago Mixed8.00.040870See
IRLIreland South8.00.0400250See
BRABrazil Puyanawa8.00.0400150See
DEUGermany DKMS - Netherlands minority0.03941374See
USAUSA NMDP Mexican or Chicano0.0393261235See
CHNChina Yunnan Bulang0.0390116See
NICNicaragua Managua7.30.0385339See
BRABrazil Mixed0.0380108See
INDIndia Tamil Nadu0.03712492See
NLDNetherlands Leiden0.03701305See
USAUSA San Diego7.40.0370496See
UGAUganda Kampala0.0370161See
PNGPapua New Guinea East New Britain Rabaul0.036060See
SAUSaudi Arabia Guraiat and Hail7.00.0360213See
FRAFrance West7.00.0356100See
MYSMalaysia Peninsular Indian7.00.0351271See
USAUSA NMDP American Indian South or Central America0.03505926See
TURTurkey pop 50.0350142See
JORJordan Amman0.0350146See
LKASri Lanka Colombo6.60.0340714See
USAUSA San Antonio Caucasian0.0333222See
NZLNew Zealand Maori with Full Ancestry6.50.033046See
RUSRussia Transbaikal Territory Buryats7.00.0330150See
USAUSA North American Native0.0320187See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0320146See
GBRUnited Kingdom pop 36.50.0320604See
CHNChina Guangzhou0.0310102See
USAUSA South Texas Hispanic0.0300194See
RUSRussia Arkhangelsk Pomor0.030063See
RUSRussia Murmansk Saomi Mixed0.030070See
COLColombia North Wiwa El Encanto0.028852See
CHNChina North Han pop 20.0282567See
USAUSA Asian pop 20.02741772See
USAUSA NMDP North American Amerindian0.026535791See
MEXMexico Mexico City Mestizo pop 20.0256234See
USAUSA NMDP Hawaiian or other Pacific Islander0.025311499See
ZAFSouth Africa Caucasians0.0250102See
ESPSpain Gipuzkoa Basque0.0250100See
NIRIreland Northern5.00.02501000See
USAUSA African American0.0240252See
CHNChina Southwest Dai0.0240124See
NZLNew Zealand Maori with Admixed History4.80.0240105See
MYSMalaysia Peninsular Chinese4.60.0232194See
CHNChina Shanxi HIV negative0.023022See
CHNChina Beijing0.023067See
RUSRussia Tuva pop 20.0230169See
NCLNew Caledonia0.022065See
HKGHong Kong Chinese BMDR0.02197595See
CHNChina South Han pop 20.02141098See
COLColombia North Chimila Amerindians0.021247See
MEXMexico Mexico City Mestizo population0.0210143See
USAUSA NMDP Alaska Native or Aleut0.02001376See
CHNChina Yunnan Province Han0.0200101See
ASMAmerican Samoa0.020051See
PAKPakistan Mixed Pathan0.0200100See
MLIMali Bandiagara0.0190138See
ZAFSouth Africa Worcester4.00.0190159See
USAUSA NMDP African0.018328557See
USAUSA Asian0.0180358See
SENSenegal Niokholo Mandenka0.0180165See
USAUSA African American pop 40.01782411See
USAUSA NMDP Chinese0.017699672See
CHNChina Marrow Donor Registry0.0170600See
SGPSingapore SGVP Malay MAS0.017089See
CHNChina Canton Han0.0170264See
CMRCameroon Beti0.0170174See
PNGPapua New Guinea Madang0.017065See
USAUSA NMDP Caribean Black0.016933328See
SGPSingapore Thai0.0160100See
CHNChina South Han0.0160284See
USAUSA South Dakota Lakota Sioux0.0150302See
CHNChina Sichuan HIV negative0.015034See
THAThailand Northeast pop 20.0150400See
INDIndia North pop 20.015072See
USAUSA NMDP African American pop 20.0149416581See
DEUGermany DKMS - China minority0.01481282See
USAUSA NMDP Vietnamese0.014343540See
CHNChina Hubei Han2.80.01393732See
CMRCameroon Bamileke0.013077See
MYSMalaysia Peninsular Malay2.30.0121951See
TWNTaiwan Han Chinese0.0120504See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.012057See
USAUSA African American Bethesda2.10.0110187See
KENKenya Luo0.0110265See
MEXMexico Chihuahua Tarahumara0.011044See
SGPSingapore SGVP Chinese CHS0.011096See
ZAFSouth Africa Natal Tamil0.010051See
SGPSingapore Javaneses0.010051See
KENKenya Nandi0.0100240See
TWNTaiwan Minnan pop 12.00.0100102See
TZATanzania Maasai1.90.0094336See
TWNTaiwan Hakka1.80.009055See
BFABurkina Faso Mossi0.009053See
VNMVietnam Hanoi Kinh pop 20.0090170See
TWNTaiwan pop 20.0080364See
MEXMexico Oaxaca Zapotec0.007090See
UGAUganda Kampala pop 20.0060175See
USAUSA NMDP Korean0.005677584See
USAUSA NMDP Filipino0.005150614See
SGPSingapore Riau Malay0.0050132See
KORSouth Korea pop 30.0050485See
USAUSA Alaska Yupik0.0040252See
GHAGhana Ga-Adangbe0.80.0038131See
USAUSA NMDP Japanese0.001924582See
JPNJapan pop 10.0010560See
JPNJapan pop 30.00101018See
JPNJapan pop 160.000818604See
RUSRussia Nizhny Novgorod, Russians0.10.00031510See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
CAFCentral African Republic Mbenzele Pygmy0.00.000036See
BFABurkina Faso Fulani0.000049See
CZECzech Republic0.0000106See
RUSRussia Nenet Mixed0.000055See
MEXMexico Oaxaca Mixtec0.0000103See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
PHLPhilippines Ivatan0.00.000050See
CHNChina North Han0.0000105See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See
ZMBZambia Lusaka0.000044See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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