Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 299 time(s) and present in 254 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
AUSAustralia Cape York Peninsula Aborigine0.3130103See
AUSAustralia Kimberly Aborigine0.305041See
FJIFiji Viti Levu Island0.263057See
INDIndia Bombay0.263059See
PNGPapua New Guinea Lowland0.260047See
CHNChina Guizhou Province Miao0.259085See
PNGPapua New Guinea Madang0.231065See
JPNJapan Fukuoka0.221086See
JPNJapan pop 1138.70.217062See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.193057See
INDIndia Northeast Mathur0.1930155See
IDNIndonesia Nusa Tenggara Islands0.192049See
INDIndia Northeast Rajbanshi0.190098See
JPNJapan pop 170.18783078See
INDIndia North pop 20.187072See
JPNJapan Central0.1830371See
MYSMalaysia Sarawak Bau Bidayuh0.180025See
MYSPeninsular Malaysia Indian32.10.1790271See
INDIndia Tamil Nadu0.17722492See
NCLNew Caledonia0.177065See
JPNJapan Nagano31.60.172957See
JPNJapan Hokkaido Wajin31.00.169371See
LKASri Lanka Colombo30.30.1670714See
GEOGeorgia Kurds0.167030See
INDIndia Northeast Rastogi0.1610196See
JPNJapan pop 20.1610916See
CHNChina Yunnan Province Yao0.158066See
JPNJapan Hyogo31.30.156032See
INDIndia Northeast Kayastha0.1550190See
TWNTaiwan pop 20.1530364See
INDIndia Northeast Mech0.151063See
INDIndia Uttar Pradesh0.1510202See
CHNChina Shanghai pop 30.147058See
PNGPapua New Guinea Lowland Wosera0.141079See
INDIndia Northeast Lachung0.138058See
WSMWestern Samoa and Tokelau0.137051See
INDIndia Northeast Sunni0.1350188See
MYSMalaysia Peninsular Chinese24.70.1314194See
PAKPakistan Kalash0.130069See
INDIndia Lucknow23.30.1290123See
CHNChina Wuhan24.00.1280121See
PNGPapua New Guinea East New Britain Rabaul0.125060See
KORSouth Korea pop 422.70.1208211See
IDNIndonesia Moluccan Islands0.120024See
USAUSA Asian pop 20.11931772See
HKGHong Kong Chinese HKBMDR. DQ and DP22.80.11891064See
CHNChina Marrow Donor Registry0.1170600See
INDIndia Northeast Shia0.1160190See
USAUSA Hawaii0.115039See
USAUSA NMDP Hawaiian or other Pacific Islander0.114911499See
CHNChina Canton Han0.1120264See
CHNChina Hong Kong and Singapore0.1110135See
PNGPapua New Guinea Highland0.109094See
TWNTaiwan Han Chinese0.1070504See
CHNChina Beijing and Xian0.1050171See
CHNChina Yunnan Province Bai0.1050128See
INDIndia Northeast Vaish0.1040198See
PNGPapua New Guinea Highland pop20.103028See
KORSouth Korea pop 10.1030324See
MYSMalaysia Peninsular Malay19.40.1020951See
CHNChina Urumqi Han0.102059See
SGPSingapore Riau Malay0.1000132See
CHNChina pop118.40.0970103See
KORSouth Korea pop 30.0960485See
MNGMongolia Tarialan Khoton0.094085See
INDIndia Delhi17.90.0939112See
IRNIran Kurd0.0900100See
IRNIran Fars Parsi0.089073See
ISRIsrael Iranian Jews0.0880101See
THAThailand Kamphaeng Phet0.088097See
CHNChina Xinjiang Province Uyghur0.087092See
CHNChina Harbin Manchu pop 20.085050See
ISRIsrael Moroccan Jews0.0830113See
CHNChina Jingpo Minority14.40.0825109See
THAThailand Northeast0.082066See
KORSouth Korea pop 215.90.0820207See
CHNChina Guangzhou Han pop 20.081086See
IRNIran Baloch0.0800100See
AREUnited Arab Emirates Abu Dhabi0.076952See
THAThailand Northeast pop 20.0750400See
LBNLebanon pop 20.0730191See
MNGMongolia Ulaanbaatar Khalkha0.073041See
CHNChina Inner Mongolia Autonomous Region Northeast14.10.0730496See
IRNIran pop 20.0710120See
USAUSA Philippines0.0710105See
IRNIran Azeri0.0700100See
TUNTunisia pop 20.0700111See
THAThailand pop 20.0690124See
USAUSA NMDP Vietnamese0.066843540See
ISRIsrael Arab0.0660109See
IDNIndonesia Java Yogyakarta Region0.065062See
VNMVietnam Hanoi Kinh pop 20.0650170See
MNGMongolia Tsaatan0.0630144See
THAThailand North Dai Lue0.062096See
ESPSpain Malaga Gypsy11.30.058180See
COKCook Islands Rarotonga0.058078See
MNGMongolia Khalkha0.0550200See
ESPSpain Andalusia Gipsy0.052099See
IRNIran Kurds0.050060See
MNGMongolia Oold0.0480104See
RUSRussia Tuva pop 20.0470169See
IRNIran Yazd Zoroastrian0.046065See
CHNChina Urumqi Uyghur7.00.044057See
TUNTunisia Ghannouch0.043082See
LBNLebanon Yuhmur0.043082See
TURTurkey pop 10.0420250See
BELBelgium pop 28.10.0420715See
POLPoland Wielkopolska Region0.040099See
RUSRussia Tuva0.0380190See
GRCGreece pop 87.20.036183See
CHNChina Urumqi Kazak0.036042See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks7.10.0360112See
MEXMexico Veracruz Xalapa7.10.035784See
DZAAlgeria pop 27.00.0356106See
ISRIsrael Ashkenazi Jews pop 20.0350132See
MEXMexico Mazatecan0.035089See
VNMVietnam Hanoi Kinh0.0350103See
RUSRussia Tuva pop30.034044See
CHNChina Wanwei, Wutou and Shanxin Islands Jing0.0340138See
GRCGreece pop 60.0331242See
GRCGreece Crete0.0300135See
ARGArgentina Gran Chaco Western Toba Pilaga0.030019See
RUSRussia Siberia Lower Yenisey Ket0.029017See
MKDMacedonia pop 30.0290172See
ISRIsrael Ashkenazi Jews0.029080See
MEXMexico Mexico City Tlalpan5.80.0288330See
DEUGermany DKMS - Turkey minority0.02854856See
ITAItaly pop 20.028053See
USAUSA San Diego5.30.0270496See
ISRIsrael Yemenite Jews0.027076See
USAUSA NMDP Caribean Indian0.027014339See
GRCGreece pop 40.026098See
ZAFSouth Africa Worcester5.00.0250159See
GRCGreece pop34.90.0248246See
HRVCroatia Krk Island Dubasnica0.024023See
CZECzech Republic0.0240106See
RUSRussia South Ural Russian4.80.0240207See
PRTMadeira pop 20.0230173See
IRNIran Gorgan0.023064See
MEXMexico Chihuahua Chihuahua City Pop 24.50.022788See
MYSMalaysia Jelebu Temuan0.021025See
TUNTunisia Gabes Arab0.021096See
USAUSA South Texas Hispanic0.0200194See
RUSRussia Siberia Sulamai Ket0.020022See
ITAItaly pop 30.0200179See
ESPSpain Andalusia0.020099See
ESPSpain Murcia0.0200173See
DEUGermany DKMS - Italy minority0.01981159See
ITAItaly Central0.0190380See
MKDMacedonia pop 20.019080See
RUSRussia Sakhalin Island Nivkhi0.019053See
RUSRussia Murmansk Saomi Mixed0.019070See
GAZGaza Palestinians0.0180165See
VNMVietnam HoaBinh Muong0.018083See
USAUSA San Francisco Caucasian0.0180220See
CHESwitzerland Luzern0.01711553See
ISRIsrael Libyan Jews0.0170119See
RUSRussia South Ural Bashkir3.40.0170146See
ITAItaly North pop 33.10.017097See
LBNLebanon Kafar Zubian0.016094See
FRAFrance Southeast3.10.0160130See
CHLChile Santiago pop 20.0160124See
TUNTunisia Gabes0.015795See
CZECzech Republic pop 23.00.015199See
CHLChile Santiago Mixed3.00.015170See
BRABrazil Southeast Caucasian2.90.0150103See
COLColombia Bogota and Medellin Mestizo0.015065See
ITAItaly Rome3.00.0150100See
ISRIsrael Non Ashkenazi Jews0.015080See
RUSRussia South Ural Tatar3.00.0150135See
RUSRussia Siberia Khanty Mansi0.015068See
RUSRussia Northwest Slavic0.0150200See
USAUSA NMDP American Indian South or Central America0.01505926See
CHESwitzerland Graubunden0.0147759See
USAUSA Hispanic pop 20.01431999See
ARGArgentina Buenos Aires2.80.0140466See
BRABrazil South Caucasian0.013773See
USAUSA San Antonio Caucasian0.0135222See
MEXMexico Nuevo Leon Mestizo2.50.013040See
ITAItaly pop 50.0130975See
RUSRussia Karelia0.01271075See
RUSRussia Siberia Irkutsk Tofalar0.012043See
SAUSaudi Arabia Guraiat and Hail2.40.0120213See
GRCGreece pop22.40.0120120See
CHESwitzerland Geneva pop 20.01151267See
USAUSA NMDP Hispanic South or Central American0.0112146714See
USAUSA Philadelphia Caucasian1.40.0110141See
ENGEngland pop 62.30.0110177See
MEXMexico Mexico City Mestizo pop 20.0107234See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,2.10.01064335See
ENGEngland North West2.00.0100298See
FRAFrance Rennes pop 30.0100200See
FRAFrance South0.0100350See
DZAAlgeria Oran0.0100100See
ARGArgentina Gran Chaco Mataco Wichi0.010049See
POLPoland Lodz0.0100103See
SAUSaudi Arabia pop 30.010050See
CHESwitzerland Zurich0.00974875See
DEUGermany Essen1.70.0090174See
RUSRussia Nenet Mixed0.009055See
PRTPortugal Center pop 20.0090562See
MEXMexico Guadalajara Mestizo0.009054See
USAUSA Caucasian pop 50.0090268See
CZECzech Republic NMDR0.00895099See
COLColombia Bogotá Cord Blood1.70.00851463See
CHESwitzerland Bern0.00853545See
HRVCroatia Gorski Kotar Region0.008063See
ISRIsrael Ethiopian Jews0.0080122See
LBNLebanon Niha el Shouff0.008061See
USAUSA NMDP Alaska Native or Aleut0.00801376See
MEXMexico Mestizo pop 40.0077269See
NICNicaragua Managua1.20.0077339See
SVNSlovenia pop 21.40.0070140See
RUSRussia Arkhangelsk Pomor0.007063See
ESPSpain Malaga1.30.0065160See
CAFCentral African Republic Aka Pygmy1.20.006093See
RUSRussia Chuvash0.006082See
MEXMexico Highlands Mestizos1.30.0060160See
CHESwitzerland Lugano0.00571169See
BRABrazil Paraná Caucasian1.10.0055641See
CRICosta Rica Central Valley Mestizo (G)1.00.0050221See
HRVCroatia Krk Island0.0050212See
MEXMexico Guanajuato and Jalisco Mestizo1.00.0050101See
NLDNetherlands Leiden0.00501305See
TUNTunisia pop 30.0050104See
CHESwitzerland Aargau-Solothurn0.00491838See
DEUGermany pop 30.90.0045111See
CHESwitzerland St Gallen0.00442113See
PRTPortugal Azores Terceira Island0.90.0044130See
NIRIreland Northern pop 20.80.0040122See
PRTAzores Terceira Island0.0040130See
FRAFrance Ceph0.0040124See
CZECzech Republic pop 30.60.0030180See
IRLIreland South0.40.0020250See
USAUSA African American pop 40.00132411See
ITAItaly Sardinia pop20.20.00101129See
ITAItaly Bergamo0.00.0000101See
MARMorocco Settat Chaouya0.00.000098See
USAUSA Alaska Yupik0.0000252See
UGAUganda Baganda0.000047See
TUNTunisia Jerba Berber0.000055See
TUNTunisia Matmata Berber0.000081See
RUSRussia Siberia Kushun Buryat0.000025See
RUSRussia Tuva Todja0.000022See
RUSRussia Siberia Polygus Evenk0.000035See
RUSRussia Siberia North East Kamchatka Koryak0.000092See
RUSRussia Siberia Gvaysugi Udege0.000025See
RUSRussia Siberia NW of Sakhalin Island Nivkh0.000032See
RUSRussia Siberia Ulchi0.000073See
RUSRussia Siberia Negidal0.000035See
RUSRussia Siberia Khabarovsk Evenki0.000025See
RUSRussia Siberia Chukotka Peninsula Chukchi0.000059See
RUSRussia Siberia Chukotka Peninsula Eskimo0.000080See
RUSRussia Siberia Dudinka Nganasan0.000024See
IRLIreland Donegal0.00.0000200See
IRLIreland Wexford0.00.0000200See
FRAFrance West0.00.0000100See
FRAFrance Rennes0.0000200See
ETHEthiopia Amhara0.000098See
ETHEthiopia Oromo0.000083See
CZECzech Republic Gypsy0.00.000034See
ECUEcuador African0.000058See
ENGEngland pop 30.00.000061See
CODCongo Kinshasa Bantu0.00.000090See
CMRCameroon Saa0.0000172See
CHESwitzerland Sion0.0000832See
CHESwitzerland Lausanne0.0000993See
CANCanada British Columbia Athabaskan0.000062See
CHESwitzerland Basel0.00001888See
BRABrazil Southeast Mulatto0.00.000042See
BRABrazil Central Plateau Xavante0.000074See
BRABrazil Guarani Nandeva0.000086See
BRABrazil North East Mixed0.0000205See
BRABrazil Guarani M bya0.000093See
ARGArgentina Kolla0.000061See
ARGArgentina Gran Chaco Eastern Toba0.0000135See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

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