Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 464 time(s) and present in 384 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
TWNTaiwan Ami64.30.388098See
COLColombia Amazon Region Coreguaje0.317030See
COLColombia/Brazil Ticuna Tarapaca NA-DHS_22 (G)52.60.289519See
COLColombia Inga NA-DHS_11 (G)50.00.281216See
BRABrazil Kaingang0.2550235See
TWNTaiwan Ami pop 20.255050See
COLColombia Waunana NA-DHS_20 (G)45.00.250020See
MEXMexico Zapotec NA-DHS_7 (G)36.80.210520See
BOLBolivia/Chile Aymara NA-DHS_13 (G)30.00.175020See
USAUSA South Dakota Lakota Sioux0.1730302See
COLColombia Jaidukama0.154039See
MEXMexico Oaxaca Zapotec0.153090See
COLColombia East Amazon Region Nukak0.150020See
COLColombia/Brazil Ticuna Arara NA-DHS_21 (G)26.70.133317See
MEXMexico Mixe NA-DHS_6 (G)25.00.125020See
TWNTaiwan Aborigine pop 20.125048See
USAUSA South Dakota Sioux0.1250101See
BOLBolivia Quechua0.123269See
USAUSA Spain Ancestry0.1200279See
ARGArgentina Gran Chaco Mataco Wichi0.110049See
MEXMexico Chichen Itza Maya (prehispanic)0.106447See
ARGArgentina Salta Wichi pop 221.10.105019See
COLColombia Wayuu NA-DHS_15 (G)20.00.100015See
MEXMexico Mazatecan0.098089See
MEXMexico Tixcacaltuyub Maya0.097067See
MEXMexico San Vicente Tancuayalab Teenek/Huastecos0.094353See
MEXMexico Oaxaca Jamiltepec Mixtec0.094096See
MEXMexico Mixtec0.093097See
MEXMexico Huasteca Region Teenek0.093055See
MEXMexico Veracruz Xalapa17.90.089384See
BRABrazil Terena15.30.085060See
BOLBolivia La Paz Aymaras0.080087See
CANCanada British Columbia Penutian0.077026See
SWESweden Southern Sami0.0760130See
MEXMexico Sinaloa Capomos Mayo Yoremes0.075060See
USAUSA South Texas Hispanic0.0740194See
MEXMexico Chihuahua Chihuahua City Pop 214.80.073988See
BOLBolivia/Peru Quechua NA-DHS_12 (G)14.30.071421See
MEXMexico Chiapas Lacandon Mayans0.0711218See
BRABrazil Central Plateau Xavante0.070074See
IRLIreland South14.00.0700250See
MEXMexico Mayan pop 20.0680163See
MEXMexico Mexico City Mestizo pop 20.0662234See
RUSRussia Bering Island Aleuts0.0625104See
CANCanada Ojibwa NA-DHS_4 (G)12.50.062516See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0622233See
USAUSA Mexican American Mestizo0.0620553See
BRABrazil Puyanawa12.00.0600150See
MEXMexico Mexico City Mestizo population0.0594143See
MEXMexico Guanajuato and Jalisco Mestizo11.90.0590101See
ARGArgentina Rosario Toba11.60.058086See
USAUSA NMDP Mexican or Chicano0.0576261235See
MEXMexico Mexico City Tlalpan11.50.0576330See
RUSRussia Siberia Negidal0.057035See
ISRIsrael Libyan Jews0.0560119See
MEXMexico Oaxaca Mixe0.055055See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.05501058See
USAUSA Hispanic pop 20.05451999See
ARGArgentina Gran Chaco Eastern Toba0.0540135See
ECUEcuador Cayapa0.0540183See
ZAFSouth Africa Caucasians0.0530102See
USAUSA NMDP North American Amerindian0.051235791See
USAUSA Southern California Mestizo9.60.049273See
USAUSA Italy Ancestry0.0490273See
MEXMexico Mexico City Mestizo pop 30.0490256See
PERPeru Titikaka Lake Uros0.0480105See
USAUSA Caucasian pop 40.04711070See
ENGEngland North West9.40.0470298See
PERPeru Titikaka Lake Uro0.0470105See
NIRIreland Northern9.30.04701000See
COLColombia Bogota and Medellin Mestizo0.046065See
USAUSA Caucasian Bethesda9.00.0450307See
ARMArmenia combined Regions0.0450100See
COLColombia Bogotá Cord Blood8.70.04441463See
MEXMexico Highlands Mestizos8.10.0440160See
FRAFrance South0.0430350See
USAUSA Caucasian pop 50.0430268See
USAUSA Mexican American Mestizo pop 30.0430116See
COLColombia North Chimila Amerindians0.042547See
USAUSA NMDP Hispanic South or Central American0.0421146714See
USAUSA NMDP American Indian South or Central America0.04205926See
ESPSpain North Cantabria0.042083See
RUSRussia Karelia0.04181075See
ISRIsrael Libya Jews0.04143739See
ISRIsrael Ethiopia Jews0.04115928See
MEXMexico Nahua/Aztec Santo Domingo Ocotitlan0.041173See
USAUSA Minnesota Olmsted0.0400339See
ESPSpain Granada0.0400280See
USAUSA Eastern European0.0400558See
RUSRussia Siberia Kushun Buryat0.040025See
USAUSA Philadelphia Caucasian7.80.0390141See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.03903830See
USAUSA NMDP European Caucasian0.03881242890See
ENGEngland Bedfordshire7.60.0387354See
ESPSpain Pas Valley0.038088See
USAUSA Hawaii0.038039See
NLDNetherlands Leiden0.03801305See
NICNicaragua Managua7.20.0374339See
DEUGermany pop 37.20.0366111See
COLColombia Guajira Peninsula Wayuu0.036088See
COLColombia Embera NA-DHS_19 (G)7.10.035714See
FRAFrance Rennes0.0350200See
SCOScotland Orkney6.70.034099See
BRABrazil Mato Grosso do Sul0.0340203See
DEUGermany DKMS - United Kingdom minority0.03401043See
ECUEcuadorean Amerindians0.033375See
GAZGaza Palestinians0.0330165See
CHNChina Xinjiang Province Uyghur0.033092See
DEUGermany DKMS - France minority0.03271406See
DEUGermany DKMS - Netherlands minority0.03171374See
RUSRussia Tundra Nentsi NA-DHS_1 (G)6.30.031316See
ZAFSouth Africa Worcester6.00.0310159See
FRAFrance Southeast6.20.0310130See
USAUSA Caucasian6.10.030961655See
DEUGermany DKMS - Austria minority0.03061698See
FRAFrance West6.00.0304100See
ETHEthiopia Oromo0.030083See
GTMGuatemala Mayan0.0300132See
ARGArgentina Gran Chaco Western Toba Pilaga0.030019See
IRNIran Azeri0.0300100See
FRAFrance Rennes pop 30.0300200See
THAThailand Bangkok pop 20.030050See
USAUSA San Francisco Caucasian0.0300220See
CZECzech Republic Romani5.90.029934See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,5.80.02934335See
RUSRussia Siberia Khanty Mansi0.029068See
MNGMongolia Hoton0.029085See
RUSRussia Siberia Lower Yenisey Ket0.029017See
MNGMongolia Tarialan Khoton0.029085See
USAUSA Caucasian Pittsburgh5.80.0290177See
BRABrazil North East Mixed0.0290205See
DEUGermany pop 80.028239689See
CANCanada Cree NA-DHS_3 (G)5.60.027818See
FRAFrance French Bone Marrow Donor Registry0.027342623See
GTMGuatemala Kaqchikel NA-DHS_8 (G)5.30.026319See
INDIndia Delhi0.0260112See
CHNChina Urumqi Uyghur5.30.026057See
CZECzech Republic NMDR0.02595099See
ISRIsrael Argentina Jews0.02584307See
CHLChile Santiago Mixed5.00.025370See
DEUGermany DKMS - German donors0.02513456066See
MEXMexico Mixtec NA-DHS_5 (G)5.00.025020See
USAUSA NMDP Alaska Native or Aleut0.02501376See
ITAItaly Rome5.00.0250100See
COLColombia West Embera0.025020See
ISRIsrael Ethiopian Jews0.0250122See
MEXMexico Nuevo Leon Mestizo5.00.025040See
LBNLebanon Yuhmur0.025082See
USAUSA San Antonio Caucasian0.0248222See
DEUGermany DKMS - Spain minority0.02421107See
PRTAzores Terceira Island0.0240130See
DEUGermany pop 60.02418862See
CHLChile Easter Island0.024021See
CHNChina Urumqi Kazak0.024042See
INDIndia North4.70.023785See
NLDNetherlands UMCU4.70.023464See
ISRIsrael USSR Jews0.023345681See
USAUSA San Diego4.60.0230496See
CUBCuba Mixed0.023078See
DEUGermany Essen4.60.0230174See
RUSRussia Northwest Slavic0.0230200See
DEUGermany DKMS - Romania minority0.02271234See
BRABrazil Paraná Caucasian4.50.0226641See
POLPoland DKMS0.022520653See
DEUGermany DKMS - Turkey minority0.02204856See
KORSouth Korea pop 30.0220485See
DEUGermany DKMS - Croatia minority0.02142057See
USAUSA NMDP Caribean Hispanic0.0211115374See
ESPSpain North Cabuerniga0.021095See
BRABrazil South Caucasian0.020873See
ESPSpain Northwest Lugo4.10.0207145See
USAUSA NMDP Middle Eastern or North Coast of Africa0.020770890See
ISRIsrael Arab pop 20.020312301See
DZAAlgeria pop 24.00.0202106See
USAUSA NMDP South Asian Indian0.0201185391See
FINFinland pop20.0200150See
TURTurkey pop 10.0200250See
ESPSpain Arratia Valley Basque0.020083See
ESPSpain Murcia0.0200173See
ESPSpain Barcelona4.00.0200941See
BRABrazil Ticuna0.020050See
GRCGreece pop 40.020098See
PRTMadeira pop 20.0200173See
DEUGermany DKMS - Portugal minority0.01961176See
ISRIsrael USA Jews0.01916058See
ISRIsrael YemenJews0.019115542See
USAUSA NMDP Caribean Indian0.019014339See
MKDMacedonia pop 20.019080See
USAUSA Caucasian Houston3.80.0190194See
COLColombia North Eastern Plains Sikuani0.019027See
GRCGreece pop 83.60.018183See
INDIndia Northeast Vaish0.0180198See
INDIndia Andhra Pradesh Golla0.0180111See
PRTAzores Central Islands0.018059See
LBNLebanon Niha el Shouff0.017061See
COLColombia West Waunana0.017030See
KORSouth Korea pop 10.0170324See
ARGArgentina Buenos Aires3.40.0170466See
KORSouth Korea pop 110.0170149See
ISRIsrael Bukhara Jews0.01682317See
DEUGermany DKMS - Bosnia and Herzegovina minority0.01651028See
LBNLebanon Kafar Zubian0.016094See
CPVCape Verde Southeastern Islands0.016062See
ISRIsrael Ashkenazi Jews pop 30.01544625See
CHLChile Mapuche0.015466See
ISRIsrael Poland Jews0.015313871See
ISRIsrael Tunisia Jews0.01529070See
CZECzech Republic pop 23.00.015199See
INDIndia Northeast Rastogi0.0150196See
INDIndia Uttar Pradesh0.0150202See
TUNTunisia pop 30.0150104See
CHNChina Harbin Korean0.0150201See
MEXMexico Sonora Seri0.015034See
ESPSpain Andalusia0.015099See
ISRIsrael Iranian Jews0.0150101See
TWNTaiwan Minnan pop 12.90.0150102See
ITAItaly Bergamo3.00.0150101See
BRABrazil Southeast Caucasian2.90.0150103See
ISRIsrael Ashkenazi Jews pop 20.0150132See
AUSAustralia Cape York Peninsula Aborigine0.0150103See
HRVCroatia pop 40.01464000See
CHLChile Santiago0.0144920See
USAUSA NMDP Southeast Asian0.014127978See
KORSouth Korea pop 42.80.0141211See
SWESweden Northern Sami0.0140154See
RUSRussia Siberia Ulchi0.014073See
CZECzech Republic0.0140106See
USAUSA NMDP Korean0.013977584See
KORSouth Korea pop 100.01384128See
PRTPortugal Azores Terceira Island2.60.0132130See
TWNTaiwan pop10.0130539See
GEOGeorgia Svaneti Region Svan0.013080See
ISRIsrael Yemenite Jews0.013076See
PRTAzores Oriental Islands0.013043See
PNGPapua New Guinea South Gidra0.0130192See
KORSouth Korea pop 60.0130800See
INDIndia Northeast Kayastha0.0130190See
INDIndia Tamil Nadu0.01282492See
ISRIsrael Druze0.01285914See
CHNChina, Xinjiang Uyghur Autonomous Region Han2.50.012570See
CHNChina Marrow Donor Registry0.0120600See
DEUGermany DKMS - Italy minority0.01211159See
ITAItaly pop 50.0120975See
CHNChina Yunnan Province Han pop 20.0120129See
RUSRussia Siberia Irkutsk Tofalar0.012043See
GRCGreece pop22.40.0120120See
INDIndia Lucknow2.50.0120123See
USAUSA Colorado Univ Cord Blood Bank African American0.0120261See
GRCGreece Crete0.0110135See
TWNTaiwan Han Chinese0.0110504See
CHNChina, Xinjiang Uyghur Autonomous Region Uyghur2.20.010971See
TUNTunisia Gabes0.010595See
COLColombia Wayu from Guajira Peninsula0.010448See
MEXMexico Mazahua0.010065See
MARMorocco Atlantic Coast Chaouya0.010098See
CHNChina Jiangsu Han0.01003238See
MEXMexico Jaltepec Mazahuas0.010050See
USAUSA African American pop 70.0100193See
TWNTaiwan Puyuma pop 20.010050See
TWNTaiwan Bunun pop 20.010050See
TWNTaiwan Tsou pop 20.010050See
TWNTaiwan Paiwan pop 20.010050See
CHNChina Beijing Shijiazhuang Tianjian Han0.0100618See
BRABrazil Mixed0.0100108See
TUNTunisia Gabes Arab0.010096See
THAThailand Kamphaeng Phet0.010097See
CHNChina Harbin Manchu pop 20.010050See
RUSRussia Siberia North East Kamchatka Koryak0.010092See
USAUSA Colorado Univ Cord Blood Bank Asian0.0100100See
VNMVietnam Hanoi Kinh0.0100103See
MKDMacedonia pop 10.0100158See
MNGMongolia Oold0.0100104See
MARMorocco Nador Metalsa0.010099See
MARMorocco Settat Chaouya0.010098See
ITAItaly North pop 32.10.010097See
KORSouth Korea pop 21.90.0100207See
PRTPortugal Center0.010050See
PRTPortugal South0.010049See
ETHEthiopia Amhara0.010098See
TWNTaiwan Puyuma2.00.010050See
TWNTaiwan Tsou2.00.010051See
MEXMexico Oaxaca Mixtec0.0100103See
DEUGermany DKMS - Greece minority0.00981894See
AREUnited Arab Emirates Abu Dhabi0.009652See
ARGArgentina Chiriguano1.80.009054See
USAUSA Southeast African American1.80.0090112See
FJIFiji Viti Levu Island0.009057See
ISRIsrael Arab0.0090109See
CHNChina Guangxi Region Maonan0.0090108See
USAUSA Asian pop 20.00911772See
USAUSA NMDP Chinese0.008899672See
TWNTaiwan Tzu Chi Morrow Donor Registry0.008746682See
CHNChina Zhejiang Han pop 20.0084833See
HKGHong Kong Chinese BMDR0.00837595See
USAUSA NMDP African American pop 20.0082416581See
INDIndia Northeast Shia0.0080190See
INDIndia Northeast Sunni0.0080188See
SAUSaudi Arabia Guraiat and Hail1.50.0080213See
JPNJapan Hyogo Osaka and Nagano0.0080195See
RUSRussia Tuva0.0080190See
CHNChina Wuhan1.70.0080121See
RUSRussia Tuva pop 20.0080169See
ISRIsrael Kavkazi Jews0.00792840See
DEUGermany DKMS - China minority0.00781282See
USAUSA NMDP Hawaiian or other Pacific Islander0.007811499See
CHNChina Hubei Han1.50.00743732See
USAUSA NMDP African0.007028557See
USAUSA African American Bethesda1.40.0070187See
IDNIndonesia Java Yogyakarta Region0.007062See
CHNChina Hong Kong and Singapore0.0070135See
SVNSlovenia pop 21.40.0070140See
SAUSaudi Arabia pop 6 (G)0.006928927See
USAUSA African American pop 40.00692411See
HKGHong Kong Chinese cord blood registry0.00683892See
USAUSA NMDP Caribean Black0.006533328See
ISRIsrael Morocco Jews0.006236718See
GRCGreece pop 60.0062242See
LKASri Lanka Colombo1.10.0060714See
TWNTaiwan Tzu Chi Cord Blood Bank0.0060710See
TUNTunisia Ghannouch0.006082See
CHNChina Canton Han0.0060264See
PNGPapua New Guinea Trobriand Island0.006081See
TUNTunisia Matmata Berber0.006081See
COKCook Islands Rarotonga0.006078See
MKDMacedonia pop 30.0060172See
ITAItaly Central0.0060380See
BRABrazil Guarani M bya0.005093See
CHNChina Lijiang Naxi0.0050100See
NZLNew Zealand Maori0.0050200See
DZAAlgeria Oran0.0050100See
MNGMongolia Khalkha pop 20.0050202See
CHNChina Yunnan Province Nu0.0050107See
IRNIran Kurd0.0050100See
TWNTaiwan pop 20.0050364See
NZLNew Zealand Maori with Admixed History1.00.0050105See
CHNChina pop11.00.0050103See
MYSMalaysia Peninsular Malay1.00.0047951See
GEOGeorgia Caucasus Tbilisi0.0042119See
USAUSA NMDP Filipino0.004150614See
CHNChina Yunnan Province Bai0.0040128See
CHNChina Wanwei, Wutou and Shanxin Islands Jing0.0040138See
JPNJapan pop 60.80.0040129See
THAThailand Northeast0.004066See
USAUSA African American pop 30.0040564See
ISRIsrael Iran Jews0.00328153See
USAUSA NMDP Japanese0.003224582See
USAUSA NMDP Vietnamese0.003143540See
RUSRussia Transbaikal Territory Buryats1.00.0030150See
ITAItaly Sardinia pop20.60.00301129See
JPNJapan pop 30.00301018See
THAThailand Northeast pop 20.0030400See
VNMVietnam Hanoi Kinh pop 20.0030170See
INDIndia Northeast Mathur0.0030155See
BRABrazil Guarani Kaiowa0.0030155See
JPNJapan pop 160.002618604See
MYSMalaysia Peninsular Chinese0.50.0026194See
USAUSA Alaska Yupik0.0020252See
GRCGreece pop30.40.0020246See
JPNJapan pop 40.40.0020525See
JPNJapan pop 20.0020916See
ZWEZimbabwe Harare Shona0.0020230See
RWARwanda Kigali Hutu and Tutsi0.0020281See
MYSMalaysia Peninsular Indian0.40.0018271See
CHNChina Jiangsu Province Han0.0018334See
JPNJapan pop 170.00163078See
JPNJapan Central0.0010371See
ISRIsrael Georgia Jews0.00084471See
ISRIsrael Iraq Jews0.000613270See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
RUSRussia Siberia Dudinka Nganasan0.000024See
RUSRussia Siberia Gvaysugi Udege0.000025See
RUSRussia Siberia NW of Sakhalin Island Nivkh0.000032See
RUSRussia Siberia Chukotka Peninsula Chukchi0.000059See
RUSRussia Siberia Chukotka Peninsula Eskimo0.000080See
PRYParaguay Aché0.000087See
PERPeru Quechua0.000044See
BRABrazil East Amazon0.000041See
ISRIsrael Moroccan Jews0.0000113See
MNGMongolia Ulaanbaatar Khalkha0.000041See
CAFCentral African Republic Aka Pygmy0.00.000093See
CODCongo Kinshasa Bantu0.00.000090See
WSMWestern Samoa and Tokelau0.000051See
CHNChina Beijing and Xian0.0000171See
RUSRussia Siberia Sulamai Ket0.000022See
RUSRussia Siberia Polygus Evenk0.000035See
NCLNew Caledonia0.000065See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
MNGMongolia Khalkha0.0000200See
BRABrazil Southeast Mixed Race0.00.000042See
MNGMongolia Tsaatan0.0000144See
BRABrazil Guarani Nandeva0.000086See
CANCanada British Columbia Athabaskan0.000062See
PRTPortugal North0.000046See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
PHLPhilippines Ivatan0.00.000050See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TUNTunisia Jerba Berber0.000055See
PNGPapua New Guinea East New Britain Tolai0.000048See
WSMSamoa West0.000022See
BORBorneo Bandjarmasin0.000021See
PNGPapua New Guinea Highland pop20.000028See
CHNChina Harbin Manchu0.0000172See
RUSRussia Siberia Khabarovsk Evenki0.000025See
CHNChina Urumqi Han0.000059See
RUSRussia Tuva pop30.000044See
RUSRussia Tuva Todja0.000022See
CPVCape Verde Northwestern Islands0.000062See
GNBGuinea Bissau0.000065See
PNGPapua New Guinea Lowland Roro0.000026See
IDNIndonesia Java0.000058See
IDNIndonesia Nusa Tenggara Islands0.000049See
IDNIndonesia Moluccan Islands0.000024See
IDNIndonesia Singaporean0.000050See
PNGPapua New Guinea Lowland0.000047See
PNGPapua New Guinea Lowland Wosera0.000079See
PNGPapua New Guinea Highland0.000094See
INDIndia Northeast Lachung0.000058See
INDIndia Northeast Mech0.000063See
INDIndia Northeast Rajbanshi0.000098See
CHNChina Yunnan Province Naxi0.0000118See
TWNTaiwan Atayal pop 20.000050See
TWNTaiwan Saisiat pop 20.000050See
TWNTaiwan Han0.000050See
TWNTaiwan Rukai pop 20.000050See
TWNTaiwan Orchid Island Yami0.000050See
ARGArgentina Rio Negro Mapuche0.000034See
ARGArgentina Chubut Tehuelche0.000023See
ARGArgentina Salta Wichi0.000024See
PRYParaguay Lengua0.000017See
JPNJapan South0.00.0000125See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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