Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.

Allele: 
   

DRB1*04:04

 
Allele reported 416 time(s) and present in 336 population(s).

Population Phenotype
Frequency (%)
Allele
Frequency
(in_decimals)
Sample
Size
IMGT/HLA¹
Database
Distribution² Haplotype³
Association
Notesª
TWNTaiwan Ami64.30.388098See
COLColombia Amazon Region Coreguaje0.317030See
BRABrazil Kaingang0.2550235See
TWNTaiwan Ami pop 20.255050See
USAUSA South Dakota Lakota Sioux0.1730302See
COLColombia Jaidukama0.154039See
MEXMexico Oaxaca Zapotec0.153090See
COLColombia East Amazon Region Nukak0.150020See
TWNTaiwan Aborigine pop 20.125048See
USAUSA South Dakota Sioux0.1250101See
BOLBolivia Quechua0.124080See
USAUSA Spain Ancestry0.1200279See
ARGArgentina Gran Chaco Mataco Wichi0.110049See
ARGArgentina Salta Wichi pop 221.10.105019See
MEXMexico Mazatecan0.098089See
MEXMexico Huasteca Region Teenek0.093055See
MEXMexico Mixtec0.093097See
BRABrazil Terena15.30.085060See
BOLBolivia Aymara0.0830102See
CANCanada British Columbia Penutian0.077026See
SWESweden Southern Sami0.0760130See
USAUSA South Texas Hispanic0.0740194See
BRABrazil Central Plateau Xavante0.070074See
IRLIreland South14.00.0700250See
MEXMexico Mayan pop 20.0680163See
MEXMexico Mexico City Mestizo pop 20.0662234See
RUSAleuts0.0625104See
USAUSA Mexican American Mestizo0.0620553See
MEXMexico Guanajuato and Jalisco Mestizo11.90.0590101See
ARGArgentina Rosario Toba11.60.058086See
USAUSA NMDP Mexican or Chicano0.0576261235See
RUSRussia Siberia Negidal0.057035See
ISRIsrael Libyan Jews0.0560119See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.05501058See
MEXMexico Oaxaca Mixe0.055055See
USAUSA Hispanic pop 20.05451999See
ARGArgentina Gran Chaco Eastern Toba0.0540135See
ECUEcuador Cayapa0.0540183See
RUSRussia Bering Island Aleut0.053085See
ZAFSouth Africa Caucasians0.0530102See
USAUSA NMDP North American Amerindian0.051235791See
USAUSA Southern California Mestizo9.60.049273See
USAUSA Italy Ancestry0.0490273See
PERPeru Titikaka Lake Uros0.0480105See
USAUSA Caucasian pop 40.04711070See
PERPeru Titikaka Lake Uro0.0470105See
NIRIreland Northern9.30.04701000See
ENGEngland North West9.40.0470298See
BGRBulgaria0.046055See
COLColombia Bogota and Medellin Mestizo0.046065See
USAUSA Caucasian Bethesda9.00.0450307See
ARMArmenia combined Regions0.0450100See
COLColombia Bogotá Cord Blood8.70.04441463See
MEXMexico Highlands Mestizos8.10.0440160See
NLDNetherlands8.50.0434447See
FRAFrance South0.0430350See
USAUSA Caucasian pop 50.0430268See
USAUSA Mexican American Mestizo pop 30.0430116See
COLColombia North Chimila Amerindians0.042547See
USAUSA NMDP Hispanic South or Central American0.0421146714See
ESPSpain North Cantabria0.042083See
RUSRussia Karelia0.04181075See
ISRIsrael Libya Jews0.04143739See
ISRIsrael Ethiopia Jews0.04115928See
RUSRussia Siberia Kushun Buryat0.040025See
USAUSA Eastern European0.0400558See
NORNorway0.0400181See
USAUSA Minnesota Olmsted0.0400339See
ESPSpain Granada0.0400280See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.03903830See
USAUSA Philadelphia Caucasian7.80.0390141See
FINFinland0.039091See
USAUSA NMDP European Caucasian0.03881242890See
ENGEngland Bedfordshire7.60.0387354See
ESPSpain Pas Valley0.038088See
NLDNetherlands Leiden0.03801305See
USAUSA Hawaii0.038039See
NICNicaragua Managua7.20.0374339See
DEUGermany pop 37.20.0366111See
COLColombia Guajira Peninsula Wayuu0.036088See
BELBelgium6.10.035099See
FRAFrance Rennes0.0350200See
DEUGermany DKMS - United Kingdom minority0.03401043See
SCOScotland Orkney6.70.034099See
BRABrazil Mato Grosso do Sul0.0340203See
GAZGaza Palestinians0.0330165See
CHNChina Xinjiang Province Uyghur0.033092See
DEUGermany DKMS - France minority0.03271406See
DEUGermany DKMS - Netherlands minority0.03171374See
ZAFSouth Africa Worcester6.00.0310159See
FRAFrance Southeast6.20.0310130See
USAUSA Caucasian6.10.030961655See
DEUGermany DKMS - Austria minority0.03061698See
FRAFrance West6.00.0304100See
ETHEthiopia Oromo0.030083See
USAUSA San Francisco Caucasian0.0300220See
GTMGuatemala Mayan0.0300132See
ARGArgentina Gran Chaco Western Toba Pilaga0.030019See
IRNIran Azeri0.0300100See
FRAFrance Rennes pop 30.0300200See
THAThailand Bangkok pop 20.030050See
CZECzech Republic Gypsy5.90.029934See
RUSRussia Siberia Khanty Mansi0.029068See
RUSRussia Siberia Lower Yenisey Ket0.029017See
MNGMongolia Hoton0.029085See
MNGMongolia Tarialan Khoton0.029085See
BRABrazil North East Mixed0.0290205See
USAUSA Caucasian Pittsburgh5.80.0290177See
DEUGermany pop 80.028239689See
INDIndia Delhi0.0260112See
CHNChina Urumqi Uyghur5.30.026057See
CZECzech Republic NMDR0.02595099See
ISRIsrael Argentina Jews0.02584307See
CHLChile Santiago Mixed5.00.025370See
SVNSlovenia5.00.0253100See
ITAItaly Rome5.00.0250100See
COLColombia West Embera0.025020See
POLPoland0.0250200See
ISRIsrael Ethiopian Jews0.0250122See
MEXMexico Nuevo Leon Mestizo5.00.025040See
LBNLebanon Yuhmur0.025082See
USAUSA San Antonio Caucasian0.0248222See
DEUGermany DKMS - Spain minority0.02421107See
PRTAzores Terceira Island0.0240130See
DEUGermany pop 60.02418862See
CHNChina Urumqi Kazak0.024042See
CHLChile Easter Island0.024021See
INDIndia North4.70.023785See
NLDNetherlands UMCU4.70.023464See
ISRIsrael USSR Jews0.023345681See
DEUGermany Essen4.60.0230174See
RUSRussia Northwest Slavic0.0230200See
CUBCuba Mixed0.023078See
USAUSA San Diego4.60.0230496See
DEUGermany DKMS - Romania minority0.02271234See
BRABrazil Paraná Caucasian4.50.0226641See
POLPoland DKMS0.022520653See
DEUGermany DKMS - Turkey minority0.02204856See
KORSouth Korea pop 30.0220485See
DEUGermany DKMS - Croatia minority0.02142057See
USAUSA NMDP Caribean Hispanic0.0211115374See
ESPSpain North Cabuerniga0.021095See
BRABrazil South Caucasian0.020873See
ESPSpain Northwest Lugo4.10.0207145See
USAUSA NMDP Middle Eastern or North Coast of Africa0.020770890See
ISRIsrael Arab pop 20.020312301See
DZAAlgeria pop 24.00.0202106See
USAUSA NMDP South Asian Indian0.0201185391See
TURTurkey pop 10.0200250See
GRCGreece pop 40.020098See
PRTMadeira pop 20.0200173See
ESPSpain Arratia Valley Basque0.020083See
ESPSpain Murcia0.0200173See
ESPSpain Barcelona4.00.0200941See
FINFinland pop20.0200150See
BRABrazil Ticuna0.020050See
DEUGermany DKMS - Portugal minority0.01961176See
ISRIsrael USA Jews0.01916058See
ISRIsrael YemenJews0.019115542See
MKDMacedonia pop 20.019080See
USAUSA Caucasian Houston3.80.0190194See
COLColombia North Eastern Plains Sikuani0.019027See
GRCGreece pop 83.60.018183See
ZAFSouth Africa Black0.0180200See
INDIndia Northeast Vaish0.0180198See
INDIndia Andhra Pradesh Golla0.0180111See
PRTAzores Central Islands0.018059See
LBNLebanon Niha el Shouff0.017061See
COLColombia West Waunana0.017030See
KORSouth Korea pop 110.0170149See
KORSouth Korea pop 10.0170324See
ARGArgentina Buenos Aires3.40.0170466See
ISRIsrael Bukhara Jews0.01682317See
DEUGermany DKMS - Bosnia and Herzegovina minority0.01651028See
CPVCape Verde Southeastern Islands0.016062See
LBNLebanon Kafar Zubian0.016094See
ISRIsrael Ashkenazi Jews pop 30.01544625See
CHLMapuche0.015466See
ISRIsrael Poland Jews0.015313871See
ISRIsrael Tunisia Jews0.01529070See
CZECzech Republic pop 23.00.015199See
INDIndia Northeast Rastogi0.0150196See
CHNChina Harbin Korean0.0150201See
AUTAustria2.50.0150200See
ISRIsrael Ashkenazi Jews pop 20.0150132See
AUSAustralia Cape York Peninsula Aborigine0.0150103See
TWNTaiwan Minnan pop 12.90.0150102See
ITAItaly Bergamo3.00.0150101See
MARMorocco0.015096See
BRABrazil Southeast Caucasian2.90.0150103See
MEXMexico Sonora Seri0.015034See
ISRIsrael Iranian Jews0.0150101See
ESPSpain Andalusia0.015099See
INDIndia Uttar Pradesh0.0150202See
TUNTunisia pop 30.0150104See
HRVCroatia pop 40.01464000See
CHLChile Santiago0.0144920See
USAUSA NMDP Southeast Asian0.014127978See
KORSouth Korea pop 42.80.0141211See
PRTMadeira0.0140185See
CZECzech Republic0.0140106See
RUSRussia Siberia Ulchi0.014073See
SWESweden Northern Sami0.0140154See
USAUSA NMDP Korean0.013977584See
KORSouth Korea pop 100.01384128See
PRTPortugal Azores Terceira Island2.60.0132130See
TWNTaiwan pop10.0130539See
ISRIsrael Yemenite Jews0.013076See
PRTAzores Oriental Islands0.013043See
KORSouth Korea pop 60.0130800See
INDIndia Northeast Kayastha0.0130190See
PNGPapua New Guinea South Gidra0.0130192See
GEOGeorgia Svaneti Region Svan0.013080See
INDIndia Tamil Nadu0.01282492See
ISRIsrael Druze0.01285914See
ITAItaly pop 50.0120975See
DEUGermany DKMS - Italy minority0.01211159See
CHNChina Yunnan Province Han pop 20.0120129See
RUSRussia Siberia Irkutsk Tofalar0.012043See
GRCGreece pop22.40.0120120See
INDIndia Lucknow2.50.0120123See
USAUSA Colorado Univ Cord Blood Bank African American0.0120261See
GRCGreece Crete0.0110135See
TWNTaiwan Han Chinese0.0110504See
TUNTunisia Gabes0.010595See
COLColombia Wayu from Guajira Peninsula0.010448See
TWNTaiwan Puyuma pop 20.010050See
TWNTaiwan Bunun pop 20.010050See
TWNTaiwan Tsou pop 20.010050See
TWNTaiwan Paiwan pop 20.010050See
CHNChina Beijing Shijiazhuang Tianjian Han0.0100618See
BRABrazil Mixed0.0100108See
THAThailand Kamphaeng Phet0.010097See
TUNTunisia Gabes Arab0.010096See
RUSRussia Siberia North East Kamchatka Koryak0.010092See
CHNChina Harbin Manchu pop 20.010050See
USAUSA African American pop 70.0100193See
MTQMartinique0.0100100See
USAUSA Colorado Univ Cord Blood Bank Asian0.0100100See
VNMVietnam Hanoi Kinh0.0100103See
MKDMacedonia pop 10.0100158See
MARMorocco Nador Metalsa0.010099See
MARMorocco Settat Chaouya0.010098See
KORSouth Korea pop 21.90.0100207See
MNGMongolia Oold0.0100104See
ITAItaly North pop 32.10.010097See
ETHEthiopia Amhara0.010098See
MEXMexico Mazahua0.010065See
CHLChile Mapuches0.0100104See
PRTPortugal Center0.010050See
PRTPortugal South0.010049See
MEXMexico Oaxaca Mixtec0.0100103See
TWNTaiwan Puyuma2.00.010050See
TWNTaiwan Tsou2.00.010051See
CHNChina Jiangsu Han0.01003238See
MARMorocco Atlantic Coast Chaouya0.010098See
DEUGermany DKMS - Greece minority0.00981894See
AREUnited Arab Emirates Abu Dhabi0.009652See
ISRIsrael Arab0.0090109See
CHNChina Guangxi Region Maonan0.0090108See
ARGArgentina Chiriguano1.80.009054See
USAUSA Southeast African American1.80.0090112See
DNKDenmark0.009055See
USAUSA Asian pop 20.00911772See
FJIFiji Viti Levu Island0.009057See
USAUSA NMDP Chinese0.008899672See
HKGHong Kong Chinese BMDR0.00837595See
USAUSA NMDP African American pop 20.0082416581See
RUSRussia Tuva pop 20.0080169See
CHNChina Wuhan1.70.0080121See
RUSRussia Tuva0.0080190See
JPNJapan Hyogo Osaka and Nagano0.0080195See
INDIndia Northeast Shia0.0080190See
INDIndia Northeast Sunni0.0080188See
SAUSaudi Arabia Guraiat and Hail1.50.0080213See
ISRIsrael Kavkazi Jews0.00792840See
DEUGermany DKMS - China minority0.00781282See
USAUSA NMDP African0.007028557See
USAUSA African American Bethesda1.40.0070187See
SVNSlovenia pop 21.40.0070140See
IDNIndonesia Java Yogyakarta Region0.007062See
CHNChina Hong Kong and Singapore0.0070135See
USAUSA African American pop 40.00692411See
HKGHong Kong Chinese cord blood registry0.00683892See
USAUSA NMDP Caribean Black0.006533328See
ISRIsrael Morocco Jews0.006236718See
GRCGreece pop 60.0062242See
MKDMacedonia pop 30.0060172See
ITAItaly Central0.0060380See
TWNTaiwan Tzu Chi Cord Blood Bank0.0060710See
COKCook Islands Rarotonga0.006078See
PNGPapua New Guinea Trobriand Island0.006081See
CHNChina Canton Han0.0060264See
TUNTunisia Ghannouch0.006082See
TUNTunisia Matmata Berber0.006081See
LKASri Lanka Colombo1.10.0060714See
DZAAlgeria Oran0.0050100See
CHNChina Yunnan Province Nu0.0050107See
NZLNew Zealand Maori0.0050200See
MNGMongolia Khalkha pop 20.0050202See
TWNTaiwan pop 20.0050364See
IRNIran Kurd0.0050100See
BRABrazil Guarani M bya0.005093See
CHNChina Lijiang Naxi0.0050100See
NZLNew Zealand Maori with Admixed History1.00.0050105See
CHNChina pop11.00.0050103See
MYSMalaysia Peninsular Malay1.00.0047951See
USAUSA NMDP Filipino0.004150614See
CHNChina Wanwei, Wutou and Shanxin Islands Jing0.0040138See
CHNChina Yunnan Province Bai0.0040128See
USAUSA African American pop 30.0040564See
JPNJapan pop 60.80.0040129See
THAThailand Northeast0.004066See
ISRIsrael Iran Jews0.00328153See
USAUSA NMDP Japanese0.003224582See
USAUSA NMDP Vietnamese0.003143540See
BRABrazil Guarani Kaiowa0.0030155See
VNMVietnam Hanoi Kinh pop 20.0030170See
INDIndia Northeast Mathur0.0030155See
THAThailand Northeast pop 20.0030400See
ITAItaly Sardinia pop20.60.00301129See
JPNJapan pop 30.00301018See
JPNJapan pop 160.002618604See
MYSMalaysia Peninsular Chinese0.50.0026194See
USAUSA Alaska Yupik0.0020252See
JPNJapan pop 20.0020916See
GRCGreece pop30.40.0020246See
JPNJapan pop 40.40.0020525See
ZWEZimbabwe Harare Shona0.0020230See
RWARwanda Kigali Hutu and Tutsi0.0020281See
CHNChina Jiangsu Province Han0.0018334See
JPNJapan pop 170.00163078See
JPNJapan Central0.0010371See
ISRIsrael Georgia Jews0.00084471See
ISRIsrael Iraq Jews0.000613270See
TUNTunisia Jerba Berber0.000055See
PNGPapua New Guinea East New Britain Tolai0.000048See
WSMSamoa West0.000022See
BORBorneo Bandjarmasin0.000021See
PNGPapua New Guinea Highland pop20.000028See
CPVCape Verde Northwestern Islands0.000062See
GNBGuinea Bissau0.000065See
PNGPapua New Guinea Lowland Roro0.000026See
TWNTaiwan Atayal pop 20.000050See
TWNTaiwan Saisiat pop 20.000050See
TWNTaiwan Han0.000050See
TWNTaiwan Rukai pop 20.000050See
TWNTaiwan Orchid Island Yami0.000050See
CHNChina Yunnan Province Naxi0.0000118See
JPNJapan0.000050See
ISRIsrael Moroccan Jews0.0000113See
MNGMongolia Ulaanbaatar Khalkha0.000041See
NIUNiue0.000070See
WSMWestern Samoa and Tokelau0.000051See
NRUNauru0.000067See
KIRKiribati0.000062See
CHNChina Beijing and Xian0.0000171See
RUSRussia Siberia Sulamai Ket0.000022See
RUSRussia Siberia Polygus Evenk0.000035See
NCLNew Caledonia0.000065See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
RUSRussia Siberia Gvaysugi Udege0.000025See
RUSRussia Siberia NW of Sakhalin Island Nivkh0.000032See
RUSRussia Siberia Chukotka Peninsula Chukchi0.000059See
RUSRussia Siberia Chukotka Peninsula Eskimo0.000080See
PRYParaguay Aché0.000087See
PERPeru Quechua0.000044See
BRABrazil East Amazon0.000041See
RUSRussia Siberia Dudinka Nganasan0.000024See
RUSRussia Siberia Khabarovsk Evenki0.000025See
CHNChina Urumqi Han0.000059See
RUSRussia Tuva pop30.000044See
RUSRussia Tuva Todja0.000022See
CHNChina Harbin Manchu0.0000172See
IDNIndonesia Java0.000058See
MYSMalaysia0.000074See
IDNIndonesia Nusa Tenggara Islands0.000049See
IDNIndonesia Moluccan Islands0.000024See
IDNIndonesia Singaporean0.000050See
WSMSamoa0.000029See
PNGPapua New Guinea Lowland0.000047See
PNGPapua New Guinea Lowland Wosera0.000079See
PNGPapua New Guinea Highland0.000094See
PHLPhilippines0.000034See
ARGArgentina Rio Negro Mapuche0.000034See
ARGArgentina Chubut Tehuelche0.000023See
ARGArgentina Salta Wichi0.000024See
PRYParaguay Lengua0.000017See
JPNJapan South0.00.0000125See
INDIndia Northeast Lachung0.000058See
INDIndia Northeast Mech0.000063See
INDIndia Northeast Rajbanshi0.000098See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
CANCanada British Columbia Athabaskan0.000062See
PRTPortugal North0.000046See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
PHLPhilippines Ivatan0.00.000050See
JAMJamaica0.0000132See
MNGMongolia Tsaatan0.0000144See
MNGMongolia Khalkha0.0000200See
BRABrazil Guarani Nandeva0.000086See
BRABrazil Southeast Mulatto0.00.000042See
CAFCentral African Republic Aka Pygmy0.00.000093See
CODCongo Kinshasa Bantu0.00.000090See

Frequency data at lower resolution for this allele can be found in links below


Allele  Number of Populations 

Notes:

* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


   

Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

support@allelefrequencies.net


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