Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 413 time(s) and present in 379 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
RUSRussia Siberia Sulamai Ket0.320022See
NZLNew Zealand Maori with Full Ancestry43.50.239046See
NZLNew Zealand Maori0.2150200See
NZLNew Zealand Maori with Admixed History40.00.2100105See
WSMWestern Samoa and Tokelau0.186051See
RUSRussia Siberia Irkutsk Tofalar0.186043See
RUSRussia Siberia Lower Yenisey Ket0.177017See
COKCook Islands0.160050See
RUSRussia Tuva Todja0.159022See
COKCook Islands Rarotonga0.147078See
RUSRussia Siberia Ulchi0.144073See
CAFCentral African Republic Aka Pygmy27.40.143093See
PNGPapua New Guinea Highland pop20.143028See
RUSRussia Tuva pop30.136044See
RUSRussia Siberia Khanty Mansi0.132068See
MYSMalaysia Peninsular Malay22.00.1272951See
RUSRussia Siberia Dudinka Nganasan0.125024See
AUSAustralia Yuendumu Aborigine0.1180191See
RUSRussia Siberia Negidal0.114035See
RUSRussia Siberia Polygus Evenk0.110035See
CHNChina Harbin Manchu pop 20.110050See
RUSRussia Sakhalin Island Nivkhi0.104053See
INDIndia Northeast Rajbanshi0.102098See
RUSRussia Siberia Khabarovsk Evenki0.100025See
NZLNew Zealand Polynesians with Admixed History18.50.093027See
RUSRussia Siberia Chukchi0.090071See
CANCanada British Columbia Athabaskan0.089062See
INDIndia Northeast Mech0.087063See
MYSMalaysia Peninsular Chinese15.50.0851194See
RUSRussia Tuva0.0840190See
CHNChina Yunnan Province Han0.0810101See
CHNChina Yunnan Province Naxi0.0810118See
CHNChina Yunnan Province Han pop 20.0810129See
WSMSamoa pop20.080050See
RUSRussia Siberia Chukotka Peninsula Chukchi0.080059See
RUSRussia Siberia Chukotka Peninsula Eskimo0.080080See
PNGPapua New Guinea Lowland0.078047See
INDIndia Northeast Lachung0.077058See
MNGMongolia Tsaatan0.0760144See
NZLNew Zealand Polynesians with Full Ancestry14.30.071021See
CHNChina Harbin Korean0.0700201See
MNGMongolia Khalkha pop 20.0700202See
RUSRussia Transbaikal Territory Buryats13.00.0700150See
RUSRussia Tuva pop 20.0690169See
COLColombia Providencia Island African0.067030See
RUSRussia Siberia Eskimo0.064570See
USAUSA Hawaii0.064039See
BRABrazil South Caucasian0.062573See
MNGMongolia Ulaanbaatar Khalkha0.061041See
ISRIsrael Yemenite Jews0.061076See
CHNChina Urumqi Kazak0.060042See
CHNChina Urumqi Han0.059059See
TWNTaiwan Paiwan11.80.059051See
JPNJapan pop 1111.30.058162See
JPNJapan Hokkaido Wajin11.30.058171See
RUSRussia Bering Island Aleuts0.0577104See
PNGPapua New Guinea Highland0.057094See
CHNChina Beijing Shijiazhuang Tianjian Han0.0560618See
JPNJapan Aichi10.90.054050See
CHNChina Urumqi Uyghur10.50.053057See
CHNChina Hong Kong and Singapore0.0520135See
ZWEZimbabwe Harare Shona0.0520230See
CZECzech Republic pop 210.10.051899See
CODCongo Kinshasa expatriates living in Belgium9.10.050075See
TWNTaiwan Rukai10.00.050050See
ISRIsrael YemenJews0.049915542See
CHNChina Harbin Manchu0.0490172See
USAUSA NMDP Korean0.048377584See
MNGMongolia Oold0.0480104See
KORSouth Korea pop 29.70.0480207See
KORSouth Korea pop 60.0470800See
BORBorneo Bandjarmasin0.047021See
USAUSA NMDP Hawaiian or other Pacific Islander0.046911499See
PNGPapua New Guinea Kapal0.046065See
TWNTaiwan Tzu Chi Morrow Donor Registry0.045546682See
USAUSA Colorado Univ Cord Blood Bank African American0.0450261See
ARGArgentina Chiriguano8.90.045054See
KORSouth Korea pop 10.0450324See
TWNTaiwan Pazeh9.10.045055See
KORSouth Korea pop 110.0440149See
FJIFiji Viti Levu Island0.044057See
KORSouth Korea pop 48.50.0434211See
CZECzech Republic0.0430106See
KORSouth Korea pop 100.04294128See
IRNIran pop 20.0420120See
DEUGermany pop 38.10.0413111See
TWNTaiwan Tzu Chi Cord Blood Bank0.0410710See
CHNChina Beijing and Xian0.0410171See
DEUGermany DKMS - China minority0.04061282See
PNGPapua New Guinea Abam0.040063See
RUSRussia Siberia Kushun Buryat0.040025See
IRNIran pop 30.0400100See
USAUSA African American pop 40.03952411See
JPNJapan pop 20.0390916See
CODCongo Kinshasa Bantu7.80.039090See
USAUSA NMDP African American pop 20.0382416581See
JPNJapan Central0.0380371See
TWNTaiwan pop10.0380539See
PNGPapua New Guinea Lowland Roro0.038026See
IDNIndonesia Moluccan Islands0.038024See
CHNChina Jiangsu Han0.03773238See
JPNJapan pop 160.037718604See
USAUSA NMDP Japanese0.037524582See
AUSAustralia Kimberly Aborigine0.037041See
TWNTaiwan pop 20.0370364See
INDIndia Northeast Sunni0.0370188See
FINFinland pop20.0370150See
TWNTaiwan Hakka5.50.036055See
BRABrazil Southeast Mulatto7.10.036042See
JPNJapan Kyoto and Osaka0.0360165See
USAUSA African American pop 70.0360193See
JPNJapan pop 30.03601018See
PRTAzores Central Islands0.036059See
JPNJapan pop 46.90.0350525See
KENKenya, Nyanza Province, Luo tribe7.00.0350100See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.035057See
JPNJapan pop 170.03453078See
USAUSA NMDP Chinese0.034299672See
PNGPapua New Guinea Dorogori0.034059See
USAUSA NMDP Caribean Black0.033833328See
KORSouth Korea pop 30.0330485See
TWNTaiwan Han Chinese0.0330504See
JPNJapan Hyogo Osaka and Nagano0.0330195See
JPNJapan South6.40.0325125See
USAUSA NMDP African0.032328557See
DEUGermany Essen6.30.0320174See
PRTPortugal South0.031049See
JPNJapan Hyogo6.30.031032See
STPSao Tome Island Angolar0.031032See
ISRIsrael Ashkenazi Jews pop 20.0310132See
TWNTaiwan Aborigine pop 20.031048See
IDNIndonesia Nusa Tenggara Islands0.030049See
STPSao Tome Island Forro0.030066See
TWNTaiwan Puyuma6.00.030050See
ISRIsrael USA Jews0.02996058See
ISRIsrael Poland Jews0.029813871See
ISRIsrael Kavkazi Jews0.02982840See
HKGHong Kong Chinese cord blood registry0.02923892See
USAUSA Minnesota Olmsted0.0290339See
CRICosta Rica African -Caribbean (G)5.80.0290102See
USAUSA Asian pop 20.02891772See
RUSRussia Karelia0.02821075See
CHNChina Marrow Donor Registry0.0280600See
SGPSingapore Riau Malay0.0280132See
CHNChina Canton Han0.0280264See
RUSRussia Northwest Slavic0.0280200See
ISRIsrael Argentina Jews0.02744307See
JPNJapan pop 65.40.0273129See
HKGHong Kong Chinese BMDR0.02697595See
CHNChina Jiangsu Province Han0.0264334See
ISRIsrael USSR Jews0.026245681See
ZAFSouth Africa Black0.0260200See
PRTAzores Oriental Islands0.026043See
SVNSlovenia pop 25.00.0253140See
TWNTaiwan Minnan pop 14.90.0250102See
CHNChina pop14.90.0250103See
ITAItaly Bergamo4.90.0250101See
MNGMongolia Khalkha0.0250200See
USAUSA Colorado Univ Cord Blood Bank Asian0.0250100See
VNMVietnam Hanoi Kinh0.0250103See
ISRIsrael Iranian Jews0.0250101See
GNQEquatorial Guinea Bioko Island Bubi0.0250100See
ZAFSouth Africa Worcester5.00.0250159See
ISRIsrael Ashkenazi Jews pop 30.02444625See
MYSMalaysia Kedah Kensiu4.80.024021See
SWESweden Southern Sami0.0240130See
COLColombia Bogota and Medellin Mestizo0.024065See
POLPoland DKMS0.023520653See
NLDNetherlands UMCU4.70.023464See
WSMSamoa West0.023022See
USAUSA San Diego4.40.0220496See
USAUSA NMDP Caribean Indian0.022014339See
HRVCroatia Krk Island Dubasnica0.022023See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0215233See
RWARwanda Kigali Hutu and Tutsi0.0210281See
CHNChina Lijiang Naxi0.0210100See
DEUGermany DKMS - United Kingdom minority0.02061043See
DEUGermany DKMS - Bosnia and Herzegovina minority0.02041028See
IDNIndonesia Singaporean0.020050See
PRTAzores Terceira Island0.0200130See
TWNTaiwan Siraya3.90.020051See
PNGPapua New Guinea Rual0.020050See
TUNTunisia pop 20.0200111See
CHNChina Yunnan Province Bai0.0200128See
ISRIsrael Bukhara Jews0.01922317See
DEUGermany pop 60.01938862See
USAUSA NMDP Caribean Hispanic0.0190115374See
INDIndia North pop 20.019072See
ISRIsrael Non Ashkenazi Jews0.019080See
CANCanada British Columbia Penutian0.019026See
TWNTaiwan Atayal3.80.0190106See
LBNLebanon pop 20.0190191See
USAUSA Philippines0.0190105See
HRVCroatia Krk Island0.0190212See
MYSMalaysia Mandailing3.70.019027See
DEUGermany pop 80.018639689See
CZECzech Republic NMDR0.01835099See
TWNTaiwan Taroko3.60.018055See
RUSRussia Chuvash0.018082See
TURTurkey pop 10.0180250See
PRTPortugal Azores Terceira Island3.50.0175130See
DEUGermany DKMS - Romania minority0.01741234See
USAUSA Caucasian pop 40.01731070See
DEUGermany DKMS - Netherlands minority0.01711374See
MEXMexico Chihuahua Chihuahua City Pop 23.40.017088See
SWESweden Northern Sami0.0170154See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.01703830See
ITAItaly Central0.0170380See
USAUSA NMDP Alaska Native or Aleut0.01701376See
USAUSA NMDP European Caucasian0.01641242890See
FRAFrance Southeast3.10.0160130See
NLDNetherlands Leiden0.01601305See
GRCGreece pop23.30.0160120See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.016096See
IRNIran Gorgan0.016064See
LBNLebanon Kafar Zubian0.016094See
TUNTunisia Gabes Arab0.016096See
DEUGermany DKMS - Greece minority0.01581894See
TUNTunisia Gabes0.015795See
DEUGermany DKMS - Turkey minority0.01564856See
HRVCroatia pop 40.01544000See
DEUGermany DKMS - France minority0.01531406See
DEUGermany DKMS - Italy minority0.01511159See
ISRIsrael Iran Jews0.01518153See
IRNIran Gorgan0.015069See
BRABrazil North East Mixed0.0150205See
ITAItaly Rome3.00.0150100See
USAUSA NMDP American Indian South or Central America0.01505926See
FRAFrance Rennes0.0150200See
BRABrazil Mixed0.0150108See
DEUGermany DKMS - Portugal minority0.01491176See
DEUGermany DKMS - Austria minority0.01441698See
DEUGermany DKMS - Croatia minority0.01432057See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,2.80.01414335See
ENGEngland pop 62.80.0140177See
USAUSA African American Bethesda2.80.0140187See
USAUSA Caucasian Pittsburgh2.80.0140177See
ESPSpain Tenerife Island0.014083See
SCOScotland Orkney2.90.014099See
USAUSA Philadelphia Caucasian2.80.0140141See
USAUSA NMDP Middle Eastern or North Coast of Africa0.013970890See
USAUSA San Antonio Caucasian0.0135222See
USAUSA NMDP North American Amerindian0.013335791See
MYSMalaysia Pahang Semai2.60.013038See
NIRIreland Northern2.50.01301000See
MKDMacedonia pop 10.0130158See
INDIndia Northeast Vaish0.0130198See
DEUGermany DKMS - Spain minority0.01271107See
ENGEngland Bedfordshire2.50.0125354See
GRCGreece pop 60.0124242See
ESPSpain Murcia0.0120173See
INDIndia Lucknow2.50.0120123See
USAUSA Hispanic pop 20.01201999See
MNGMongolia Tarialan Khoton0.012085See
IRLIreland South2.40.0120250See
MNGMongolia Hoton0.012085See
MEXMexico Nuevo Leon Mestizo2.50.012040See
ITAItaly pop 50.0120975See
INDIndia North2.30.011585See
COLColombia Bogotá Cord Blood2.20.01131463See
USAUSA Caucasian pop 50.0110268See
CHNChina Xinjiang Province Uyghur0.011092See
ZAFSouth Africa Caucasians0.0110102See
PRTPortugal North0.011046See
USAUSA San Francisco Caucasian0.0110220See
BRABrazil Paraná Caucasian2.20.0109641See
USAUSA NMDP Hispanic South or Central American0.0109146714See
USAUSA NMDP Filipino0.010550614See
ISRIsrael Arab pop 20.010512301See
POLPoland Wielkopolska Region0.010099See
ENGEngland North West2.00.0100298See
SDNSudan Mixed2.00.0100200See
CHLChile Santiago Mixed2.00.010070See
ARGArgentina Buenos Aires1.90.0100466See
USAUSA South Texas Hispanic0.0100194See
BRABrazil Southeast Caucasian1.90.0100103See
TWNTaiwan Saisiat2.00.010051See
ESPSpain Barcelona2.00.0100941See
BRABrazil Mato Grosso do Sul0.0100203See
RUSRussia Siberia North East Kamchatka Koryak0.010092See
MARMorocco Souss Region0.010098See
MYSMalaysia Sarawak Iban0.010051See
THAThailand Bangkok pop 20.010050See
GRCGreece pop 40.010098See
FRAFrance Rennes pop 30.0100200See
AREUnited Arab Emirates Abu Dhabi0.009652See
USAUSA NMDP Southeast Asian0.009427978See
USAUSA NMDP Mexican or Chicano0.0091261235See
GAZGaza Palestinians0.0090165See
VNMVietnam Hanoi Kinh pop 20.0090170See
JPNJapan Nagano1.80.009057See
BRABrazil Terena1.70.009060See
NICNicaragua Managua1.80.0090339See
CRICosta Rica Guanacaste Mestizo (G)1.80.0090110See
INDIndia Andhra Pradesh Golla0.0090111See
FRAFrance French Bone Marrow Donor Registry0.008542623See
COLColombia Barranquilla0.0080188See
PNGPapua New Guinea Madang0.008065See
GRCGreece pop31.60.0080246See
IRNIran Kurds0.008060See
CHNChina Wuhan1.70.0080121See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.00701058See
USAUSA Caucasian Bethesda1.40.0070307See
CHNChina Wanwei, Wutou and Shanxin Islands Jing0.0070138See
INDIndia Northeast Mathur0.0070155See
IDNIndonesia Java Yogyakarta Region0.007062See
USAUSA Southern California Mestizo1.40.007073See
GRCGreece Crete0.0070135See
JORJordan Amman0.0070146See
INDIndia Tamil Nadu0.00672492See
ISRIsrael Tunisia Jews0.00679070See
ISRIsrael Morocco Jews0.006036718See
MKDMacedonia pop 30.0060172See
ETHEthiopia Oromo0.006083See
PRTMadeira pop 20.0060173See
GEOGeorgia Svaneti Region Svan0.006080See
MEXMexico Veracruz Xalapa1.20.006084See
MEXMexico Highlands Mestizos1.30.0060160See
PNGPapua New Guinea Trobriand Island0.006081See
USAUSA NMDP South Asian Indian0.0060185391See
ISRIsrael Georgia Jews0.00584471See
USAUSA NMDP Vietnamese0.005443540See
MARMorocco Nador Metalsa0.005099See
ITAItaly North pop 31.10.005097See
ARMArmenia combined Regions0.0050100See
DZAAlgeria pop 21.00.0050106See
ISRIsrael Moroccan Jews0.0050113See
INDIndia Delhi0.0050112See
IRNIran Kurd0.0050100See
AUSAustralia Cape York Peninsula Aborigine0.0050103See
THAThailand North Dai Lue0.005096See
INDIndia Northeast Rastogi0.0050196See
MEXMexico Guanajuato and Jalisco Mestizo1.00.0050101See
COLColombia Antioquia Paisa0.0050100See
ESPSpain Andalusia Gipsy0.005099See
ISRIsrael Arab0.0050109See
ISRIsrael Iraq Jews0.004613270See
CRICosta Rica Central Valley Mestizo (G)0.90.0045221See
MEXMexico Mexico City Mestizo pop 20.0043234See
USAUSA Alaska Yupik0.0040252See
GTMGuatemala Mayan0.0040132See
USAUSA Mexican American Mestizo pop 30.0040116See
INDIndia Northeast Kayastha0.0030190See
INDIndia Northeast Shia0.0030190See
CHNChina Yunnan Hani0.0030150See
MEXMexico Mexico City Tlalpan0.60.0030330See
NICNicaragua Mestizo (G)0.60.0030155See
INDIndia Uttar Pradesh0.0030202See
ISRIsrael Libya Jews0.00273739See
CHLChile Santiago0.0024920See
MEXMexico Chiapas Lacandon Mayans0.0023218See
USAUSA South Dakota Lakota Sioux0.0020302See
LKASri Lanka Colombo0.30.0010714See
ISRIsrael Druze0.00065914See
ISRIsrael Ethiopia Jews0.00025928See
PRYParaguay Lengua0.000017See
CZECzech Republic Gypsy0.00.000034See
RUSRussia Siberia Gvaysugi Udege0.000025See
RUSRussia Siberia NW of Sakhalin Island Nivkh0.000032See
PNGPapua New Guinea East New Britain Rabaul0.000060See
NCLNew Caledonia0.000065See
IRNIran Azeri0.0000100See
BRABrazil Central Plateau Xavante0.000074See
ARGArgentina Gran Chaco Eastern Toba0.0000135See
ARGArgentina Gran Chaco Mataco Wichi0.000049See
ARGArgentina Gran Chaco Western Toba Pilaga0.000019See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Tao0.00.000050See
PRTPortugal Center0.000050See
TWNTaiwan Thao0.00.000030See
PHLPhilippines Ivatan0.00.000050See
TWNTaiwan Ami0.00.000098See
MARMorocco Settat Chaouya0.000098See
BRABrazil Kaingang0.0000235See
BRABrazil Guarani M bya0.000093See
USAUSA Caucasian Houston0.00.0000194See
ETHEthiopia Amhara0.000098See
PNGPapua New Guinea East New Britain Tolai0.000048See
TUNTunisia Jerba Berber0.000055See
TUNTunisia Matmata Berber0.000081See
ISRIsrael Libyan Jews0.0000119See
ISRIsrael Ethiopian Jews0.0000122See
PNGPapua New Guinea Lowland Wosera0.000079See
IDNIndonesia Java0.000058See
LBNLebanon Niha el Shouff0.000061See
LBNLebanon Yuhmur0.000082See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

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