Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 459 time(s) and present in 412 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
SAUSaudi Arabia35.30.195618See
TZATanzania Maasai32.10.1770336See
ETHEthiopia Amhara0.173098See
ISRIsrael Ethiopia Jews0.17225928See
ISRIsrael Iran Jews0.17218153See
ETHEthiopia Oromo0.169083See
ISRIsrael Ethiopian Jews0.1600122See
CODCongo Kinshasa expatriates living in Belgium31.80.159075See
ISRIsrael Iranian Jews0.1500101See
GMBGambia pop 326.10.1440939See
RWARwanda Kigali Hutu and Tutsi0.1410281See
ISRIsrael Georgia Jews0.13764471See
MARMorocco Nador Metalsa0.111099See
CHNChina, Xinjiang Uyghur Autonomous Region Uyghur19.60.108771See
KORSouth Korea pop 10.1030324See
KORSouth Korea pop 418.50.0972211See
KORSouth Korea pop 100.09444128See
KORSouth Korea pop 60.0940800See
CODCongo Kinshasa Bantu16.70.094090See
JPNJapan pop 1117.70.092862See
KORSouth Korea pop 215.50.0890207See
SAUSaudi Arabia Guraiat and Hail17.40.0890213See
KORSouth Korea pop 30.0870485See
KORSouth Korea pop 110.0870149See
USAUSA NMDP Korean0.086277584See
USAUSA NMDP African0.084228557See
COLColombia Providencia Island African0.083030See
COLColombia San Basilio de Palenque0.083042See
JPNJapan Nagano15.80.082357See
MYSMalaysia Perak Grik Jehai0.080025See
ISRIsrael Iraq Jews0.079813270See
NLDNetherlands UMCU15.60.078164See
USAUSA African American Bethesda14.10.0770187See
JPNJapan Central0.0770371See
USAUSA Colorado Univ Cord Blood Bank African American0.0760261See
CHNChina Harbin Korean0.0750201See
JPNJapan Hyogo Osaka and Nagano0.0740195See
ISRIsrael Druze0.07365914See
USAUSA NMDP African American pop 20.0730416581See
ISRIsrael Poland Jews0.072113871See
ISRIsrael USA Jews0.07076058See
JPNJapan South13.60.0704125See
USAUSA NMDP Caribean Black0.070333328See
USAUSA Caucasian Houston12.20.0670194See
ZWEZimbabwe Harare Shona0.0660230See
USAUSA African American pop 70.0650193See
USAUSA African American pop 40.06452411See
JPNJapan pop 170.06413078See
JPNJapan pop 30.06401018See
JPNJapan pop 412.40.0640525See
CHESwitzerland Zurich0.06344875See
BRABrazil Puyanawa12.00.0630150See
GNQEquatorial Guinea Bioko Island Bubi0.0630100See
GEOGeorgia Caucasus Tbilisi0.0630119See
CHNChina, Xinjiang Uyghur Autonomous Region Han12.50.062570See
ISRIsrael Ashkenazi Jews pop 30.06244625See
CUBCuba Mixed0.061078See
BRABrazil Southeast Mixed Race11.90.060042See
ITAItaly Rome12.00.0600100See
MYSMalaysia Sarawak Bau Bidayuh0.060025See
MARMorocco Atlantic Coast Chaouya0.060098See
JPNJapan pop 611.60.0597129See
ISRIsrael Argentina Jews0.05964307See
JPNJapan pop 160.059518604See
INDIndia Delhi0.0590112See
CHESwitzerland Sion0.0590832See
FRAFrance Southeast11.50.0590130See
CHESwitzerland Aargau-Solothurn0.05871838See
ISRIsrael USSR Jews0.058045681See
ARGArgentina Buenos Aires11.60.0580466See
CHNChina Jiangsu Han0.05793238See
USAUSA NMDP Japanese0.057524582See
USAUSA NMDP Caribean Indian0.057014339See
CHESwitzerland Graubunden0.0567759See
USAUSA San Antonio Caucasian0.0563222See
ESPSpain Andalusia0.056099See
MARMorocco Settat Chaouya0.056098See
MARMorocco Souss Region0.056098See
MNGMongolia Tsaatan0.0560144See
DEUGermany pop 310.80.0555111See
USAUSA NMDP Caribean Hispanic0.0554115374See
JPNJapan Kyoto and Osaka0.0550165See
ISRIsrael YemenJews0.054915542See
ISRIsrael Tunisia Jews0.05469070See
ISRIsrael Morocco Jews0.054336718See
CHNChina Jiangsu Province Han0.0543334See
CHESwitzerland Bern0.05433545See
CAFCentral African Republic Aka Pygmy10.70.054093See
BRABrazil Mato Grosso do Sul0.0540203See
HRVCroatia Krk Island Vrbnik0.054028See
PRTPortugal North0.054046See
DEUGermany DKMS - Italy minority0.05391159See
DEUGermany DKMS - Netherlands minority0.05371374See
CHESwitzerland Lugano0.05321169See
JPNJapan pop 20.0530916See
USAUSA Minnesota Olmsted0.0530339See
USAUSA NMDP Middle Eastern or North Coast of Africa0.052470890See
USAUSA Caucasian Pittsburgh10.40.0520177See
ESPSpain Murcia0.0520173See
USAUSA Caucasian pop 40.05191070See
RUSRussia Tuva0.0510190See
PRTPortugal South0.051049See
LBNLebanon Niha el Shouff0.051061See
ISRIsrael Non Ashkenazi Jews0.051080See
CHESwitzerland St Gallen0.05032113See
BRABrazil Mixed0.0500108See
FRAFrance Rennes pop 30.0500200See
COLColombia Northwest Choco0.050020See
RUSRussia Tuva pop 20.0500169See
TURTurkey pop 10.0500250See
CHESwitzerland Basel0.04941888See
CHESwitzerland Luzern0.04911553See
BRABrazil Southeast Caucasian9.70.0490103See
ISRIsrael Libya Jews0.04883739See
USAUSA NMDP European Caucasian0.04881242890See
DEUGermany DKMS - Spain minority0.04881107See
ITAItaly pop 50.0480975See
USAUSA Caucasian Bethesda8.30.0480307See
SWESweden Southern Sami0.0480130See
NLDNetherlands Leiden0.04801305See
MNGMongolia Oold0.0480104See
ISRIsrael Arab pop 20.047912301See
DEUGermany DKMS - Portugal minority0.04781176See
DEUGermany DKMS - France minority0.04731406See
JPNJapan Hyogo9.40.047032See
ESPSpain Barcelona9.10.0460941See
FRAFrance French Bone Marrow Donor Registry0.045242623See
FRAFrance Rennes0.0450200See
DZAAlgeria Oran0.0450100See
DEUGermany DKMS - United Kingdom minority0.04501043See
BRABrazil North East Mixed0.0450205See
KENKenya, Nyanza Province, Luo tribe9.00.0450100See
RUSRussia Tuva pop30.045044See
RUSRussia Tuva Todja0.045022See
USAUSA Eastern European0.0450558See
USAUSA San Francisco Caucasian0.0450220See
USAUSA San Diego8.30.0450496See
HRVCroatia pop 40.04414000See
ITAItaly pop 48.60.04404575See
MKDMacedonia pop 20.044080See
CHNChina Urumqi Uyghur8.80.044057See
SENSenegal Dakar8.90.0440112See
DEUGermany DKMS - Bosnia and Herzegovina minority0.04381028See
DEUGermany DKMS - China minority0.04331282See
FINFinland pop20.0430150See
ISRIsrael Ashkenazi Jews pop 20.0430132See
SCOScotland Orkney8.70.043099See
USAUSA Philadelphia Caucasian8.50.0430141See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.04303830See
CHESwitzerland Lausanne0.0423993See
DEUGermany DKMS - German donors0.04233456066See
DEUGermany pop 60.04228862See
USAUSA NMDP Hispanic South or Central American0.0421146714See
DEUGermany DKMS - Croatia minority0.04202057See
IRNIran Kurd pop 20.042060See
HRVCroatia Krk Island0.0420212See
MYSMalaysia Jelebu Temuan0.042025See
DEUGermany pop 80.041839689See
USAUSA Caucasian8.20.041861655See
IRNIran Saqqez-Baneh Kurds0.041760See
DEUGermany DKMS - Austria minority0.04121698See
ESPSpain Las Alpujarras0.041285See
CHESwitzerland Geneva pop 20.04101267See
USAUSA South Texas Hispanic0.0410194See
USAUSA Caucasian pop 50.0410268See
DZAAlgeria pop 28.00.0408106See
GRCCretan Islanders0.0403124See
ESPSpain Granada0.0400280See
CHNChina Harbin Manchu pop 20.040050See
ISRIsrael Yemenite Jews0.040076See
USAUSA NMDP American Indian South or Central America0.04005926See
RUSRussia Siberia Kushun Buryat0.040025See
MYSMalaysia Patani8.00.040025See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,7.70.03914335See
ISRIsrael Libyan Jews0.0390119See
GAZGaza Palestinians0.0390165See
USAUSA Hispanic pop 20.03881999See
COLColombia Bogotá Cord Blood7.70.03861463See
AREUnited Arab Emirates Abu Dhabi0.038552See
COLColombia Bogota and Medellin Mestizo0.038065See
PRTMadeira pop 20.0380173See
RUSRussia Northwest Slavic0.0380200See
ZAFSouth Africa Worcester8.00.0380159See
USAUSA NMDP North American Amerindian0.037935791See
DEUGermany DKMS - Greece minority0.03721894See
GRCGreece Crete0.0370135See
ISRIsrael Arab0.0370109See
MNGMongolia Ulaanbaatar Khalkha0.037041See
RUSRussia Siberia Khanty Mansi0.037068See
ZAFSouth Africa Caucasians0.0370102See
USAUSA Asian pop 20.03621772See
SVNSlovenia pop 27.10.0361140See
GRCGreece pop 87.20.036183See
INDIndia North7.10.036185See
INDIndia Northeast Rajbanshi0.036098See
ITAItaly North pop 37.20.036097See
TUNTunisia Jerba Berber0.036055See
TWNTaiwan Hakka7.30.036055See
DEUGermany DKMS - Turkey minority0.03574856See
FRAFrance West7.00.0356100See
JPNJapan Hokkaido Wajin7.00.035671See
ISRIsrael Kavkazi Jews0.03522840See
USAUSA NMDP Mexican or Chicano0.0350261235See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.03501058See
MNGMongolia Khalkha0.0350200See
USAUSA Southern California Mestizo6.80.034673See
NICNicaragua Managua6.60.0344339See
BRABrazil Paraná Caucasian6.90.0343641See
PAKPakistan Karachi Parsi0.034091See
USAUSA Mexican American Mestizo pop 30.0340116See
TWNTaiwan Minnan pop 16.90.0340102See
USAUSA NMDP South Asian Indian0.0337185391See
MYSMalaysia Peninsular Indian6.60.0332271See
GRCGreece pop 60.0331242See
GRCGreece pop26.50.0330120See
ENGEngland Bedfordshire6.50.0330354See
CHNChina Marrow Donor Registry0.0330600See
NIRIreland Northern6.40.03301000See
RUSRussia Transbaikal Territory Buryats7.00.0330150See
TWNTaiwan pop10.0330539See
PRTAzores Terceira Island0.0320130See
ISRIsrael Moroccan Jews0.0320113See
INDIndia Uttar Pradesh0.0320202See
MKDMacedonia pop 10.0320158See
TUNTunisia Gabes0.031595See
CHNChina Hubei Han6.20.03113732See
CHNChina Yunnan Province Han pop 20.0310129See
AREUnited Arab Emirates Pop 10.0310570See
LKASri Lanka Colombo6.20.0310714See
USAUSA Colorado Univ Cord Blood Bank Asian0.0310100See
TUNTunisia Matmata Berber0.031081See
TUNTunisia Gabes Arab0.031096See
GRCGreece pop36.10.0309246See
CHLChile Mapuche0.030866See
CZECzech Republic NMDR0.03015099See
GRCGreece pop 40.030098See
CHNChina Yunnan Province Han0.0300101See
INDIndia Northeast Vaish0.0300198See
IRNIran Azeri0.0300100See
ITAItaly Bergamo5.90.0300101See
PRTPortugal Center0.030050See
ZAFSouth Africa Limpopo Venda0.0300117See
INDIndia North UCBB6.00.02995849See
CZECzech Republic Romani5.90.029934See
INDIndia Central UCBB6.00.02994204See
ITAItaly Central0.0290380See
INDIndia Lucknow5.80.0290123See
ESPSpain Tenerife Island0.029083See
TUNTunisia pop 30.0290104See
USAUSA NMDP Southeast Asian0.028227978See
SWESweden Northern Sami0.0280154See
CHNChina Canton Han0.0280264See
MEXMexico Oaxaca Zapotec0.028090See
CHNChina Zhejiang Han pop 20.0270833See
ECUEcuadorean Amerindians0.026775See
INDIndia Tamil Nadu0.02652492See
INDIndia South UCBB5.30.026411446See
INDIndia Northeast Lachung0.026058See
DEUGermany Essen5.20.0260174See
TWNTaiwan pop 20.0260364See
INDIndia West UCBB5.20.02585829See
CZECzech Republic pop 25.10.025899See
ENGEngland pop 65.10.0250177See
ISRIsrael Ashkenazi Jews0.025080See
MEXMexico Guanajuato and Jalisco Mestizo5.00.0250101See
RUSRussia Karelia0.02491075See
POLPoland DKMS0.024820653See
CHLChile Santiago0.0246920See
USAUSA NMDP Chinese0.024299672See
USAUSA NMDP Alaska Native or Aleut0.02401376See
TUNTunisia Ghannouch0.024082See
CHNChina Southwest Dai0.0240124See
CZECzech Republic0.0240106See
INDIndia Northeast Kayastha0.0240190See
IRLIreland South4.80.0240250See
DEUGermany DKMS - Romania minority0.02311234See
CHNChina Beijing Shijiazhuang Tianjian Han0.0230618See
MKDMacedonia pop 30.0230172See
STPSao Tome Island Forro0.023066See
RUSRussia Siberia Irkutsk Tofalar0.023043See
MEXMexico Tixcacaltuyub Maya0.022467See
MEXMexico Highlands Mestizos4.40.0220160See
HRVCroatia Krk Island Dubasnica0.022023See
ARGArgentina Chubut Tehuelche0.022023See
TWNTaiwan Han Chinese0.0220504See
MEXMexico Mexico City Mestizo pop 20.0214234See
MEXMexico Mexico City Mestizo pop 30.0210256See
IRNIran Fars Parsi0.021073See
HKGHong Kong Chinese cord blood registry0.02043892See
INDIndia East UCBB4.10.02042403See
CHLChile Santiago Mixed4.00.020270See
ESPSpain Arratia Valley Basque0.020083See
INDIndia Northeast Mathur0.0200155See
TWNTaiwan Siraya3.90.020051See
SAUSaudi Arabia pop 30.020050See
VNMVietnam Hanoi Kinh0.0200103See
WSMWestern Samoa and Tokelau0.020051See
COLColombia North Wiwa El Encanto0.019252See
USAUSA NMDP Vietnamese0.019143540See
USAUSA Philippines0.0190105See
SGPSingapore Riau Malay0.0190132See
NZLNew Zealand Polynesians with Admixed History3.70.019027See
COKCook Islands Rarotonga0.019078See
CANCanada British Columbia Penutian0.019026See
ITAItaly pop 20.019053See
LBNLebanon Yuhmur0.019082See
MNGMongolia Tarialan Khoton0.018085See
MNGMongolia Hoton0.018085See
INDIndia Northeast Rastogi0.0180196See
ESPSpain North Cantabria0.018083See
MYSMalaysia Kelantan3.60.018028See
VNMVietnam Hanoi Kinh pop 20.0180170See
IRNIran Yazd0.017956See
HKGHong Kong Chinese BMDR0.01717595See
ARGArgentina Rosario Toba3.50.017086See
CHNChina Urumqi Han0.017059See
CHNChina Harbin Manchu0.0170172See
INDIndia Northeast UCBB3.40.0169296See
USAUSA NMDP Hawaiian or other Pacific Islander0.016411499See
MYSMalaysia Peninsular Malay3.30.0163951See
RUSRussia Siberia Chukchi0.016071See
INDIndia Northeast Mech0.016063See
INDIndia Northeast Shia0.0160190See
IRNIran Gorgan0.016064See
LBNLebanon Kafar Zubian0.016094See
ESPSpain North Cabuerniga0.016095See
ESPSpain Pas Valley0.016088See
IRNIran Tabriz Azeris0.015597See
CHNChina, Xinjiang Uyghur Autonomous Region Kazakh3.00.015252See
ARMArmenia combined Regions0.0150100See
GTMGuatemala Mayan0.0150132See
MNGMongolia Khalkha pop 20.0150202See
BOLBolivia Quechua0.014569See
IDNIndonesia Java pop 20.014036See
INDIndia Andhra Pradesh Golla0.0140111See
RUSRussia Siberia Ulchi0.014073See
BRABrazil South Caucasian0.013973See
GEOGeorgia Svaneti Region Svan0.013080See
IDNIndonesia Java Western2.50.0130236See
NZLNew Zealand Maori0.0130200See
PRTAzores Oriental Islands0.013043See
MYSMalaysia Peninsular Chinese2.60.0129194See
IRNIran pop 20.0125120See
IDNIndonesia Sundanese and Javanese0.0120201See
MEXMexico Nuevo Leon Mestizo2.50.012040See
CHNChina Wuhan2.50.0120121See
CHNChina Urumqi Kazak0.012042See
PERPeru Lamas City Lama0.012083See
MEXMexico Veracruz Xalapa2.40.011984See
THAThailand Bangkok pop 30.0110187See
MEXMexico Mexico City Tlalpan2.10.0106330See
MEXMexico Mexico City Mestizo population0.0105143See
USAUSA NMDP Filipino0.010350614See
THAThailand Northeast pop 20.0100400See
USAUSA South Dakota Sioux0.0100101See
THAThailand Northeast0.010066See
THAThailand Bangkok pop 20.010050See
PERPeru Titikaka Lake Uros0.0100105See
NZLNew Zealand Maori with Admixed History1.90.0100105See
MYSMalaysia Sarawak Iban0.010051See
MYSMalaysia Sabah Dusun0.010048See
JPNJapan Hokkaido Ainu0.010050See
IDNIndonesia Singaporean0.010050See
INDIndia Northeast Sunni0.0100188See
IRNIran Kurd0.0100100See
ISRIsrael Bukhara Jews0.00902317See
INDIndia North pop 20.009072See
BRABrazil Terena1.70.009060See
ARGArgentina Chiriguano1.80.009054See
PERPeru Titikaka Lake Uro0.0090105See
PRTAzores Central Islands0.009059See
PRTPortugal Azores Terceira Island1.80.0088130See
IDNIndonesia Java Yogyakarta Region0.007062See
MEXMexico Nahua/Aztec Santo Domingo Ocotitlan0.006873See
BOLBolivia La Paz Aymaras0.006087See
RUSRussia Chuvash0.006082See
VNMVietnam HoaBinh Muong0.006083See
MEXMexico Chihuahua Chihuahua City Pop 21.10.005788See
MEXMexico Mixtec0.005097See
MEXMexico Oaxaca Jamiltepec Mixtec0.005096See
MEXMexico Oaxaca Mixtec0.0050103See
CHNChina pop11.00.0050103See
CHNChina Xinjiang Province Uyghur0.005092See
CHNChina Yunnan Bulang0.0040116See
CHNChina Yunnan Province Naxi0.0040118See
JORJordan Amman0.0030146See
MEXMexico Chiapas Lacandon Mayans0.0023218See
USAUSA South Dakota Lakota Sioux0.0020302See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000646682See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
USAUSA Alaska Yupik0.0000252See
RUSRussia Siberia Eskimo0.000070See
RUSRussia Siberia Negidal0.000035See
RUSRussia Siberia Khabarovsk Evenki0.000025See
THAThailand North Dai Lue0.000096See
STPSao Tome Island Angolar0.000032See
PRYParaguay Lengua0.000017See
PHLPhilippines Ivatan0.00.000050See
PNGPapua New Guinea Lowland0.000047See
PNGPapua New Guinea Lowland Wosera0.000079See
PNGPapua New Guinea Highland0.000094See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Sindhi0.0000101See
IDNIndonesia Nusa Tenggara Islands0.000049See
IDNIndonesia Moluccan Islands0.000024See
CHNChina Hong Kong and Singapore0.0000135See
CHNChina Beijing and Xian0.0000171See
BRABrazil Guarani Nandeva0.000086See
BRABrazil Kaingang0.0000235See
BRABrazil Guarani M bya0.000093See
ARGArgentina Salta Wichi0.000024See
ARGArgentina Rio Negro Mapuche0.000034See
ARGArgentina Gran Chaco Eastern Toba0.0000135See
ARGArgentina Gran Chaco Mataco Wichi0.000049See
ARGArgentina Gran Chaco Western Toba Pilaga0.000019See
BRABrazil Central Plateau Xavante0.000074See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CANCanada British Columbia Athabaskan0.000062See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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