Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 375 time(s) and present in 353 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MYSMalaysia Sabah Dusun0.521048See
MYSMalaysia Sabah Kadazan0.500057See
IDNIndonesia Nusa Tenggara Islands0.479049See
IDNIndonesia Moluccan Islands0.463024See
USAUSA Philippines0.3860105See
PNGPapua New Guinea Wipim0.355055See
USAUSA NMDP Filipino0.352950614See
PNGPapua New Guinea Woigi0.346026See
PNGPapua New Guinea Wuroi0.338034See
MYSMalaysia Perak Grik Jehai0.300025See
MYSMalaysia Champa44.80.276029See
PNGPapua New Guinea Abam0.270063See
PNGPapua New Guinea Lowland0.247047See
PNGPapua New Guinea Ume0.244090See
PNGPapua New Guinea Podare0.233043See
IDNIndonesia Java Western41.10.2330236See
PNGPapua New Guinea Lowland Roro0.231026See
PNGPapua New Guinea South Gidra0.2240192See
MYSMalaysia Mandailing40.70.222027See
PNGPapua New Guinea Kuru0.217046See
PNGPapua New Guinea Wonie0.216051See
IDNIndonesia Java Yogyakarta Region0.208062See
PNGPapua New Guinea Madang0.200065See
PNGPapua New Guinea Rual0.200050See
THAThailand Northeast0.196066See
THAThailand North Dai Lue0.193096See
MYSMalaysia Sarawak Iban0.186051See
THAThailand Northeast pop 20.1830400See
MYSMalaysia Peninsular Malay32.80.1814951See
PNGPapua New Guinea Dorogori0.178059See
PNGPapua New Guinea Iamega0.177079See
PNGPapua New Guinea Kapal0.177065See
IDNIndonesia Singaporean0.170050See
FJIFiji Viti Levu Island0.167057See
THAThailand Kamphaeng Phet0.165097See
MYSMalaysia Sarawak Bau Bidayuh0.160025See
MYSMalaysia Pahang Semai26.30.158038See
IDNIndonesia Java0.146058See
MYSMalaysia Kedah Kensiu28.60.143021See
MYSMalaysia Kelantan28.60.143028See
MYSMalaysia Kedah Baling Kensiu0.140025See
JPNJapan South25.60.1374125See
AUSAustralia Kimberly Aborigine0.134041See
CHNChina Southwest Dai0.1330124See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.132057See
JPNJapan pop 424.40.1310525See
JPNJapan pop 1124.20.129362See
PNGPapua New Guinea Lowland Wosera0.129079See
USAUSA Hawaii0.128039See
VNMVietnam HoaBinh Muong0.127083See
CHNChina Yunnan Bulang0.1250116See
THAThailand Bangkok pop 30.1230187See
PNGPapua New Guinea Highland0.121094See
SGPSingapore Riau Malay0.1200132See
MYSMalaysia Patani24.00.120025See
JPNJapan pop 621.70.1151129See
NCLNew Caledonia0.115065See
JPNJapan Kyoto and Osaka0.1120165See
INDIndia North21.10.111785See
JPNJapan Nagano21.10.111757See
MYSMalaysia Sarawak Bidayuh0.110050See
JPNJapan pop 170.11003078See
INDIndia Northeast Mathur0.1090155See
USAUSA NMDP South Asian Indian0.1073185391See
JPNJapan pop 160.106518604See
ESPSpain Malaga Gypsy20.00.105580See
USAUSA NMDP Southeast Asian0.104627978See
JPNJapan pop 100.1020332See
JPNJapan Central0.1000371See
PNGPapua New Guinea East New Britain Rabaul0.100060See
JPNJapan pop 30.09901018See
USAUSA NMDP Japanese0.096724582See
MYSPeninsular Malaysia Indian18.80.0959271See
INDIndia Tamil Nadu0.08832492See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0880233See
INDIndia Tamil Nadu Chennai16.70.0873137See
INDIndia Uttar Pradesh0.0870202See
JPNJapan pop 20.0870916See
INDIndia Northeast Vaish0.0860198See
CHNChina pop116.50.0860103See
IRNIran Kurd0.0850100See
USAUSA NMDP Hawaiian or other Pacific Islander0.083511499See
MYSMalaysia Jelebu Temuan0.083025See
LKASri Lanka Colombo15.70.0820714See
USAUSA Asian pop 20.08091772See
IRNIran Baloch0.0800100See
VNMVietnam Hanoi Kinh0.0780103See
ISRIsrael Iranian Jews0.0770101See
PNGPapua New Guinea Trobriand Island0.074081See
JPNJapan Hyogo Osaka and Nagano0.0740195See
JPNJapan Hokkaido Wajin14.10.073171See
MNGMongolia Hoton0.072085See
ISRIsrael Moroccan Jews0.0720113See
ISRIsrael Druze0.07175914See
CHNChina Xinjiang Province Uyghur0.071092See
USAUSA NMDP Vietnamese0.070943540See
CHNChina Yunnan Hani0.0700150See
INDIndia Lucknow14.10.0700123See
THAThailand Bangkok pop 20.070050See
INDIndia Northeast Kayastha0.0680190See
AREUnited Arab Emirates Abu Dhabi0.067352See
ISRIsrael Georgia Jews0.06614471See
DZAAlgeria Oran0.0660100See
CHNChina Guangxi Region Maonan0.0650108See
JPNJapan Hyogo12.50.063032See
JPNJapan Aichi10.90.062050See
VNMVietnam Hanoi Kinh pop 20.0620170See
INDIndia Northeast Rastogi0.0610196See
CZECzech Republic Gypsy11.80.060834See
CHNChina Hong Kong and Singapore0.0590135See
INDIndia Delhi0.0590112See
ISRIsrael Arab0.0570109See
NZLNew Zealand Polynesians with Admixed History11.10.056027See
ISRIsrael Morocco Jews0.055036718See
IRNIran Azeri0.0550100See
CHNChina Canton Han0.0530264See
CHNChina Beijing and Xian0.0530171See
INDIndia Northeast Lachung0.052058See
AUSAustralia Cape York Peninsula Aborigine0.0510103See
IRNIran pop 20.0500120See
KORSouth Korea pop 49.50.0486211See
BRABrazil Southeast Mulatto9.50.048042See
NZLNew Zealand Polynesians with Full Ancestry9.50.048021See
INDIndia Northeast Mech0.047063See
ISRIsrael Arab pop 20.047012301See
USAUSA Colorado Univ Cord Blood Bank Asian0.0460100See
CHNChina Yunnan Province Han0.0450101See
GRCGreece Crete0.0440135See
TUNTunisia Ghannouch0.043082See
MEXMexico Mazatecan0.042089See
MNGMongolia Tsaatan0.0420144See
ISRIsrael YemenJews0.041315542See
TURTurkey pop 10.0400250See
MNGMongolia Oold0.0390104See
WSMWestern Samoa and Tokelau0.039051See
MYSMalaysia Peninsular Chinese7.70.0387194See
ISRIsrael Kavkazi Jews0.03802840See
AUSAustralia Yuendumu Aborigine0.0380191See
IRNIran Yazd Zoroastrian0.038065See
CHNChina Harbin Korean0.0370201See
KORSouth Korea pop 10.0370324See
GRCGreece pop 87.20.036183See
ISRIsrael Ashkenazi Jews pop 30.03604625See
CHNChina Urumqi Kazak0.036042See
INDIndia Northeast Rajbanshi0.036098See
ISRIsrael Poland Jews0.035913871See
ISRIsrael Argentina Jews0.03584307See
ISRIsrael Tunisia Jews0.03579070See
ARMArmenia combined Regions0.0350100See
GRCGreece pop 40.035098See
CHNChina Urumqi Uyghur7.00.035057See
MNGMongolia Khalkha0.0350200See
INDIndia Northeast Sunni0.0340188See
ISRIsrael Iran Jews0.03358153See
GRCGreece pop 60.0331242See
RUSRussia Tuva0.0330190See
KORSouth Korea pop 30.0330485See
KORSouth Korea pop 60.0320800See
ISRIsrael USSR Jews0.031945681See
USAUSA NMDP Korean0.031877584See
HKGHong Kong Chinese BMDR0.03157595See
KORSouth Korea pop 100.03104128See
ISRIsrael Ashkenazi Jews pop 20.0310132See
DZAAlgeria pop 26.00.0304106See
ISRIsrael USA Jews0.03026058See
ARGArgentina Gran Chaco Western Toba Pilaga0.030019See
SDNSudan Mixed6.00.0300200See
CHNChina Jiangsu Han0.02983238See
USAUSA NMDP Middle Eastern or North Coast of Africa0.029270890See
HKGHong Kong Chinese cord blood registry0.02903892See
RUSRussia Tuva pop 20.0290169See
RUSRussia Bering Island Aleuts0.0288104See
ISRIsrael Iraq Jews0.027513270See
CHNChina Marrow Donor Registry0.0270600See
IRNIran Fars Parsi0.027073See
CHNChina Yunnan Province Han pop 20.0270129See
USAUSA NMDP Chinese0.026699672See
DEUGermany DKMS - Turkey minority0.02604856See
CHNChina Harbin Manchu0.0260172See
MKDMacedonia pop 30.0260172See
GRCGreece pop34.90.0248246See
BRABrazil Southeast Caucasian4.80.0240103See
KORSouth Korea pop 110.0240149See
USAUSA San Diego4.20.0240496See
DEUGermany DKMS - Greece minority0.02371894See
TWNTaiwan Han Chinese0.0230504See
TWNTaiwan pop 20.0230364See
CHNChina Beijing Shijiazhuang Tianjian Han0.0230618See
TWNTaiwan Tzu Chi Cord Blood Bank0.0230710See
CHNChina Jiangsu Province Han0.0227334See
ISRIsrael Libya Jews0.02213739See
ZAFSouth Africa Worcester4.00.0220159See
KORSouth Korea pop 24.30.0220207See
CHNChina Wuhan4.10.0210121See
INDIndia Northeast Shia0.0210190See
TUNTunisia Gabes Arab0.021096See
GAZGaza Palestinians0.0210165See
TUNTunisia Gabes0.021095See
USAUSA NMDP Caribean Indian0.020014339See
TWNTaiwan pop10.0200539See
ISRIsrael Yemenite Jews0.020076See
PRTMadeira pop 20.0200173See
USAUSA South Texas Hispanic0.0200194See
ESPSpain Murcia0.0200173See
CHNChina Harbin Manchu pop 20.020050See
COKCook Islands Rarotonga0.019078See
CANCanada British Columbia Penutian0.019026See
CZECzech Republic0.0190106See
ISRIsrael Ashkenazi Jews0.019080See
ISRIsrael Non Ashkenazi Jews0.019080See
DEUGermany DKMS - Italy minority0.01891159See
SVNSlovenia pop 23.60.0181140See
USAUSA San Francisco Caucasian0.0180220See
ARGArgentina Chiriguano3.60.018054See
ARGArgentina Buenos Aires3.40.0170466See
USAUSA Caucasian Pittsburgh3.40.0170177See
CHNChina Yunnan Province Naxi0.0170118See
ISRIsrael Libyan Jews0.0170119See
DEUGermany DKMS - China minority0.01681282See
TWNTaiwan Tzu Chi Morrow Donor Registry0.016546682See
GRCGreece pop23.30.0160120See
FRAFrance Southeast3.10.0160130See
MKDMacedonia pop 10.0160158See
CZECzech Republic pop 23.00.015199See
CHLChile Santiago Mixed3.00.015170See
ITAItaly North pop 33.90.015097See
ITAItaly Rome3.00.0150100See
RUSRussia Siberia Khanty Mansi0.015068See
POLPoland Wielkopolska Region0.015099See
ITAItaly pop 50.0140975See
MEXMexico Mexico City Tlalpan2.70.0136330See
USAUSA Hispanic pop 20.01331999See
PRTAzores Oriental Islands0.013043See
DEUGermany DKMS - Croatia minority0.01292057See
RUSRussia Karelia0.01271075See
HRVCroatia pop 40.01254000See
ISRIsrael Bukhara Jews0.01232317See
MEXMexico Nuevo Leon Mestizo2.50.012040See
RUSRussia Siberia Irkutsk Tofalar0.012043See
MKDMacedonia pop 20.012080See
ESPSpain Barcelona2.40.0120941See
ITAItaly Central0.0120380See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.01201058See
MEXMexico Veracruz Xalapa2.40.011984See
CHESwitzerland Geneva pop 20.01191267See
CHESwitzerland Zurich0.01174875See
USAUSA NMDP Mexican or Chicano0.0117261235See
USAUSA San Antonio Caucasian0.0113222See
USAUSA NMDP Hispanic South or Central American0.0111146714See
USAUSA NMDP American Indian South or Central America0.01105926See
USAUSA NMDP Alaska Native or Aleut0.01101376See
USAUSA Philadelphia Caucasian1.40.0110141See
RUSRussia Tuva pop30.011044See
ARGArgentina Gran Chaco Mataco Wichi0.011049See
CHLChile Santiago0.0109920See
USAUSA NMDP Caribean Hispanic0.0108115374See
MEXMexico Mexico City Mestizo pop 20.0107234See
CHESwitzerland Lugano0.01041169See
DEUGermany DKMS - Bosnia and Herzegovina minority0.01051028See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,2.10.01044335See
RUSRussia Transbaikal Territory Buryats2.00.0100150See
BRABrazil Mato Grosso do Sul0.0100203See
MEXMexico Mixtec0.010097See
FRAFrance Rennes pop 30.0100200See
MEXMexico Guanajuato and Jalisco Mestizo2.00.0100101See
BRABrazil Mixed0.0100108See
ESPSpain Andalusia0.010099See
JPNJapan Hokkaido Ainu0.010050See
PRTPortugal Center0.010050See
USAUSA Caucasian Houston2.00.0100194See
DEUGermany DKMS - Austria minority0.00961698See
DEUGermany DKMS - Portugal minority0.00961176See
DEUGermany pop 80.009239689See
DEUGermany DKMS - Spain minority0.00931107See
DEUGermany pop 31.80.0090111See
USAUSA Eastern European0.0090558See
ITAItaly pop 41.70.00904575See
USAUSA Caucasian pop 50.0090268See
RUSRussia Sakhalin Island Nivkhi0.009053See
MEXMexico Highlands Mestizos1.90.0090160See
PRTAzores Central Islands0.009059See
DEUGermany Essen1.70.0090174See
DEUGermany DKMS - France minority0.00871406See
COLColombia Bogotá Cord Blood1.70.00851463See
CHESwitzerland St Gallen0.00852113See
CHESwitzerland Luzern0.00821553See
CHESwitzerland Graubunden0.0082759See
DEUGermany DKMS - Romania minority0.00801234See
FRAFrance Rennes0.0080200See
ENGEngland pop 61.70.0080177See
CHNChina Urumqi Han0.008059See
COLColombia Bogota and Medellin Mestizo0.008065See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.00803830See
CZECzech Republic NMDR0.00805099See
USAUSA Caucasian pop 40.00771070See
POLPoland DKMS0.007320653See
USAUSA NMDP European Caucasian0.00721242890See
USAUSA Caucasian Bethesda1.40.0070307See
CHESwitzerland Sion0.0069832See
BRABrazil South Caucasian0.006973See
CHESwitzerland Basel0.00661888See
TUNTunisia Matmata Berber0.006081See
CAFCentral African Republic Aka Pygmy1.20.006093See
GEOGeorgia Svaneti Region Svan0.006080See
NICNicaragua Managua1.20.0060339See
DEUGermany pop 60.00588862See
BRABrazil Paraná Caucasian1.10.0055641See
CHESwitzerland Aargau-Solothurn0.00521838See
SAUSaudi Arabia Guraiat and Hail1.00.0050213See
MNGMongolia Khalkha pop 20.0050202See
MEXMexico Oaxaca Mixtec0.0050103See
NLDNetherlands Leiden0.00501305See
USAUSA NMDP Caribean Black0.004833328See
USAUSA NMDP North American Amerindian0.004535791See
PRTPortugal Azores Terceira Island0.90.0044130See
CHESwitzerland Bern0.00433545See
DEUGermany DKMS - Netherlands minority0.00441374See
USAUSA NMDP African0.004028557See
USAUSA Mexican American Mestizo pop 30.0040116See
ISRIsrael Ethiopian Jews0.0040122See
NIRIreland Northern0.70.00401000See
PRTAzores Terceira Island0.0040130See
USAUSA Colorado Univ Cord Blood Bank African American0.0040261See
DEUGermany DKMS - United Kingdom minority0.00341043See
CHESwitzerland Lausanne0.0032993See
COLColombia Barranquilla0.0025188See
USAUSA NMDP African American pop 20.0023416581See
IRLIreland South0.40.0020250See
BRABrazil North East Mixed0.0020205See
USAUSA African American pop 40.00172411See
ENGEngland Bedfordshire0.30.0015354See
ISRIsrael Ethiopia Jews0.00055928See
IRLIreland Donegal0.00.0000200See
IRLIreland Wexford0.00.0000200See
TUNTunisia Jerba Berber0.000055See
ESPSpain Malaga0.00.0000160See
USAUSA Alaska Yupik0.0000252See
ITAItaly Bergamo0.00.0000101See
MEXMexico Oaxaca Zapotec0.000090See
PRTPortugal North0.000046See
CANCanada British Columbia Athabaskan0.000062See
PRTPortugal South0.000049See
BRABrazil Guarani Nandeva0.000086See
BRABrazil Kaingang0.0000235See
BRABrazil Guarani M bya0.000093See
FRAFrance West0.00.0000100See
USAUSA African American Bethesda0.00.0000187See
RUSRussia Siberia Ulchi0.000073See
RUSRussia Siberia Negidal0.000035See
RUSRussia Siberia Khabarovsk Evenki0.000025See
RUSRussia Tuva Todja0.000022See
RUSRussia Siberia Kushun Buryat0.000025See
BRABrazil Central Plateau Xavante0.000074See
ARGArgentina Gran Chaco Eastern Toba0.0000135See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

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