Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.



Allele reported 227 time(s) and present in 217 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CHNChina Yunnan Hani0.1800150See
CHNChina Han HIV negative0.156072See
CHNChina Henan HIV negative0.156016See
GHAGhana Ga-Adangbe22.90.1221131See
ARGArgentina Gran Chaco Eastern Toba21.60.1160135See
JPNJapan pop 160.110918604See
JPNJapan pop 30.10901018See
JPNJapan Central0.1070371See
ARGArgentina Gran Chaco Western Toba Pilaga21.40.107019See
JPNJapan pop 50.1040117See
ESPSpain Andalusia Romani0.101099See
USAUSA NMDP Japanese0.099024582See
ISRIsrael Iran Jews0.08318153See
MLIMali Bandiagara0.0830138See
IRNIran Tabriz Azeris0.082597See
MYSMalaysia Patani16.00.080025See
SGPSingapore SGVP. Indian INS0.075086See
USAUSA NMDP South Asian Indian0.0745185391See
INDIndia Tamil Nadu0.07132492See
ISRIsrael Druze0.06915914See
CHNChina Shanxi HIV negative0.068022See
LKASri Lanka Colombo12.90.0670714See
ISRIsrael Kavkazi Jews0.06652840See
ISRIsrael Morocco Jews0.065436718See
MYSMalaysia Peninsular Indian11.80.0627271See
IRNIran Yazd0.062556See
CHNChina Beijing0.061067See
USAUSA NMDP Southeast Asian0.059227978See
CHNChina Sichuan HIV negative0.059034See
AREUnited Arab Emirates Abu Dhabi0.057752See
CHNChina Yunnan Bulang0.0560116See
ISRIsrael Iraq Jews0.055213270See
ISRIsrael Bukhara Jews0.05442317See
CHNChina Uyghur HIV negative0.053019See
ISRIsrael Arab pop 20.052212301See
ISRIsrael YemenJews0.051415542See
ISRIsrael Tunisia Jews0.05119070See
ISRIsrael Argentina Jews0.04914307See
INDIndia Delhi pop 28.80.049090See
MEXMexico Mestizo9.80.049041See
ISRIsrael Ashkenazi Jews pop 30.04894625See
ISRIsrael Poland Jews0.048713871See
ARGArgentina Rosario Toba9.30.047086See
USAUSA South Texas Hispanic0.0470194See
USAUSA Hispanic0.0450234See
MEXMexico Oaxaca Zapotec0.045090See
ISRIsrael USSR Jews0.043845681See
ISRIsrael USA Jews0.04256058See
GRCGreece pop 88.40.042283See
IRNIran Kurd pop 20.042060See
MYSMalaysia Jelebu Temuan0.042025See
SGPSingapore SGVP Malay MAS0.042089See
CHNChina Jiangsu Province Han0.0418334See
IRNIran Saqqez-Baneh Kurds0.041760See
CHNChina Jiangsu Han0.04003238See
ISRIsrael Libya Jews0.04003739See
MYSMalaysia Peninsular Malay11.90.0394951See
RUSRussia Bering Island Aleuts0.0385104See
ISRIsrael Georgia Jews0.03804471See
MEXMexico Oaxaca Mixe0.037055See
BRABrazil Puyanawa7.30.0370150See
USAUSA Asian pop 20.03681772See
MEXMexico Mixtec0.036097See
MEXMexico Oaxaca Jamiltepec Mixtec0.036096See
USAUSA NMDP Middle Eastern or North Coast of Africa0.033170890See
SDNSudan Mixed6.50.0330200See
ITAItaly North pop 36.70.033097See
ARGArgentina Gran Chaco Mataco Wichi6.50.033049See
USAUSA NMDP Caribean Indian0.032014339See
CHESwitzerland Graubunden0.0303759See
CHESwitzerland Aargau-Solothurn0.03021838See
ARMArmenia combined Regions0.0300100See
KORSouth Korea pop 100.02984128See
CHESwitzerland St Gallen0.02842113See
CHNChina Guangzhou Han0.0280106See
CHNChina Southwest Dai0.0280124See
KORSouth Korea pop 30.0280485See
MEXMexico Mexico City Mestizo population0.0280143See
CHESwitzerland Geneva pop 20.02701267See
USAUSA Hispanic pop 20.02681999See
USAUSA NMDP Mexican or Chicano0.0260261235See
DEUGermany DKMS - Turkey minority0.02564856See
DEUGermany DKMS - Greece minority0.02531894See
USAUSA NMDP Korean0.025277584See
CHESwitzerland Lugano0.02471169See
NICNicaragua Managua4.80.0241339See
JORJordan Amman0.0240146See
SAUSaudi Arabia pop 6 (G)0.024028927See
MEXMexico Veracruz Xalapa4.80.023884See
DEUGermany DKMS - China minority0.02341282See
MYSMalaysia Peninsular Chinese4.10.0232194See
USAUSA San Francisco Caucasian0.0230220See
MEXMexico Chihuahua Chihuahua City Pop 24.50.022788See
CHNChina Marrow Donor Registry0.0220600See
ZAFSouth Africa Worcester4.00.0220159See
MEXMexico Mexico City Mestizo pop 20.0214234See
MEXMexico Chichen Itza Maya (prehispanic)0.021347See
USAUSA NMDP Caribean Hispanic0.0213115374See
USAUSA African American pop 80.0210605See
USAUSA San Diego3.80.0210496See
TUNTunisia Gabes0.021095See
USAUSA NMDP Hispanic South or Central American0.0205146714See
USAUSA NMDP Caribean Black0.020433328See
SRBSerbia pop 22.90.0200102See
CHNChina Hubei Han4.00.02003732See
DEUGermany DKMS - Italy minority0.01981159See
CHESwitzerland Zurich0.01814875See
CHESwitzerland Basel0.01801888See
ESPSpain Andalusia0.018099See
USAUSA Asian0.0180358See
RUSRussia Karelia0.01731075See
USAUSA NMDP African0.017228557See
CHNChina Beijing Shijiazhuang Tianjian Han0.0170618See
MYSMalaysia Champa3.50.017029See
CHESwitzerland Lausanne0.0165993See
MEXMexico Chiapas Lacandon Mayans0.0161218See
USAUSA African American0.0160252See
UGAUganda Kampala0.0160161See
SGPSingapore SGVP Chinese CHS0.016096See
STPSao Tome Island Angolar0.016032See
USAUSA African American Bethesda3.20.0160187See
USAUSA NMDP African American pop 20.0154416581See
POLPoland DKMS0.015420653See
CHLChile Santiago Mixed3.00.015170See
DEUGermany DKMS - Croatia minority0.01512057See
USAUSA Philadelphia Caucasian3.00.0150141See
COLColombia Bogotá Cord Blood2.90.01471463See
HRVCroatia pop 40.01464000See
USAUSA African American pop 40.01432411See
USAUSA NMDP American Indian South or Central America0.01405926See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,2.80.01404335See
CUBCuba Caucasian2.90.014070See
DEUGermany DKMS - Romania minority0.01381234See
USAUSA NMDP Chinese0.013499672See
PRTAzores Oriental Islands0.013043See
DEUGermany DKMS - Austria minority0.01301698See
CHESwitzerland Bern0.01223545See
MEXMexico Mexico City Tlalpan2.40.0121330See
SAUSaudi Arabia Guraiat and Hail2.40.0120213See
USAUSA San Antonio Caucasian0.0120222See
ITAItaly North Pavia0.012081See
ITAItaly pop 50.0120975See
CUBCuba Mixed Race2.40.012042See
FRAFrance Southeast2.30.0120130See
CZECzech Republic NMDR0.01175099See
DEUGermany DKMS - Spain minority0.01171107See
DEUGermany pop 80.011339689See
TWNTaiwan Tzu Chi Morrow Donor Registry0.011146682See
TWNTaiwan Tzu Chi Cord Blood Bank0.0110710See
USAUSA Caucasian pop 20.0110265See
IDNIndonesia Java Western2.10.0110236See
BRABrazil Belo Horizonte Caucasian2.10.011095See
USAUSA NMDP Hawaiian or other Pacific Islander0.010311499See
DEUGermany DKMS - Bosnia and Herzegovina minority0.01021028See
DEUGermany DKMS - France minority0.01001406See
ENGEngland North West2.00.0100298See
JPNJapan Hokkaido Ainu0.010050See
TWNTaiwan Han Chinese0.0100504See
SGPSingapore Chinese2.00.0100149See
PRTPortugal Center0.010050See
HKGHong Kong Chinese cord blood registry0.00953892See
BRABrazil Terena1.70.009060See
PRTAzores Central Islands0.009059See
USAUSA European American pop 20.00901245See
DEUGermany DKMS - Portugal minority0.00891176See
USAUSA NMDP European Caucasian0.00891242890See
DEUGermany DKMS - German donors0.00883456066See
USAUSA NMDP Vietnamese0.008643540See
USAUSA Eastern European0.0080558See
TWNTaiwan pop 20.0080364See
STPSao Tome Island Forro0.008066See
IRNIran Gorgan0.008064See
NLDNetherlands UMCU1.60.007864See
CHLChile Mapuche0.007766See
HKGHong Kong Chinese BMDR0.00767595See
DEUGermany pop 60.00758862See
NLDNetherlands Leiden0.00701305See
MKDMacedonia pop 40.0070216See
MARMorocco Nador Metalsa pop 20.007073See
USAUSA NMDP Alaska Native or Aleut0.00701376See
USAUSA NMDP North American Amerindian0.006635791See
USAUSA Caucasian pop 40.00651070See
DEUGermany DKMS - Netherlands minority0.00621374See
GEOGeorgia Svaneti Region Svan0.006080See
HKGHong Kong Chinese1.20.0060569See
CHNChina Canton Han0.0060264See
IRLIreland South1.20.0060250See
ITAItaly Bergamo1.00.0060101See
USAUSA NMDP Filipino0.005750614See
CHESwitzerland Luzern0.00561553See
CHNChina Guangzhou0.0050102See
CHNChina Yunnan Province Han0.0050101See
PERPeru Titikaka Lake Uro0.0050105See
PERPeru Titikaka Lake Uros0.0050105See
USAUSA North American Native0.0050187See
TWNTaiwan pop 30.0050212See
PRTPortugal Azores Terceira Island0.90.0044130See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0043233See
PRTAzores Terceira Island0.0040130See
DEUGermany DKMS - United Kingdom minority0.00381043See
NIRIreland Northern0.60.00301000See
VNMVietnam Hanoi Kinh pop 20.0030170See
CHESwitzerland Sion0.0024832See
ISRIsrael Ethiopia Jews0.00135928See
MEXMexico Oaxaca Mixtec0.0000103See
KENKenya Nandi0.0000240See
KENKenya Luo0.0000265See
CHNChina North Han0.0000105See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
PRTPortugal South0.000049See
PRTPortugal North0.000046See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian Bethesda0.00.0000307See
ZAFSouth Africa Natal Zulu0.00.0000100See
ZMBZambia Lusaka0.000044See

See also higher resolution data of this allele

Allele  Number of Populations 
 B*52:01:01 103 
 B*52:01:02 61 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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