Latest developments in AFND:
o New definition of geographical regions
o Working in quality of data

Introduction

The Allele Frequency Net Database (AFND) provides a central source, freely available to all, for the storage of allele frequencies from different polymorphic areas in the Human Genome. Users can contribute the results of their work into one common database and can perform database searches on information already available.

We have currently collected data in allele, haplotype and genotype format. However, the success of this website will depend on you to contribute your data.

Please cite this website using our last publication: Allele frequency net: a database and online repository for immune gene frequencies in worldwide populations. Gonzalez-Galarza FF, Christmas S, Middleton D and Jones AR Nucleic Acid Research 2011, 39, D913-D919. [Full Text]

You should also cite the original publication report of the data in your references.

Polymorphic Region	Population Studies	Gene/Allele Data	Haplotype Data	Genotype Data
HLA	928	913	367	-
KIR	229	228	-	146
Cytokine	114	114	-	-
MIC	60	60	21	-
Totals	1,331	1,315	388	146

The current number of frequencies stored in our database is: 98,873 (HLA), 5,738 (KIR), 3,618 (Cytokine) and 760 (MIC) from 4,559,080 individuals.

We have updated the website with the new IMGT/HLA nomenclature guidelines.
IMGT/HLA last Update: 3.15.0, 17 January, 2014. | IPD-KIR last Update: 2.5.0, 11 October, 2013.

               

AFND is part of EUROSTAM (an FP7-HEALTH collaborative project) to facilitate transplantation of highly sensitized patients.

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