Allele Frequencies in World Populations
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The Allele Frequency Net Database


Latest developments in AFND:
o New definition of geographical regions
o Data quality guidelines in AFND
o HLA Epitope Frequency section
o HLA and Adverse Drug Reactions section
o KIR and Disease Associations section

Introduction

Allele Frequencies in Worldwide Populations

The Allele Frequency Net Database (AFND) provides a central source, freely available to all, for the storage of allele frequencies from different polymorphic areas in the Human Genome. Users can contribute the results of their work into one common database and can perform database searches on information already available.

We have currently collected data in allele, haplotype and genotype format. However, the success of this website will depend on you to contribute your data.

Please cite this website using our last publication: Allele frequency net: a database and online repository for immune gene frequencies in worldwide populations. Gonzalez-Galarza FF, Christmas S, Middleton D and Jones AR Nucleic Acid Research 2011, 39, D913-D919. [Full Text]

You should also cite the original publication report of the data in your references.

Database information


Polymorphic Region Population Studies Gene/Allele Data Haplotype Data Genotype Data
HLA10251007370 -
KIR231230 - 148
Cytokine114114 - -
MIC606021 -
Totals 1,430 1,411 391 148

The current number of frequencies stored in our database is: 114,994 (HLA), 5,770 (KIR), 3,618 (Cytokine) and 760 (MIC) from 10,284,340 individuals.

We have updated the website with the new IMGT/HLA nomenclature guidelines.
IMGT/HLA last Update: 3.15.0, 17 January, 2014. | IPD-KIR last Update: 2.5.0, 11 October, 2013.

               

AFND is part of EUROSTAM (an FP7-HEALTH collaborative project) to facilitate transplantation of highly sensitized patients.



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