Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 480 time(s) and present in 417 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
RUSRussia Chuvash0.183082See
INDIndia Northeast Shia0.1600190See
IRNIran Baloch0.1500100See
FINFinland pop20.1470150See
MEXMexico Jaltepec Mazahuas0.130050See
MEXMexico Mazahua0.130065See
RUSRussia Karelia0.12741075See
ESPSpain Gipuzkoa Basque0.1270100See
HRVCroatia Krk Island Vrbnik0.125028See
SVNSlovenia pop 223.00.1225140See
INDIndia Northeast Sunni0.1170188See
DEUGermany DKMS - Netherlands minority0.11211374See
USAUSA Caucasian Houston21.20.1120194See
FRAFrance West21.00.1111100See
NLDNetherlands UMCU18.80.109464See
USAUSA San Antonio Caucasian0.1081222See
NLDNetherlands Leiden0.10701305See
GRCGreece pop 40.107098See
CZECzech Republic pop 220.20.106699See
DEUGermany Essen20.70.1060174See
ARGArgentina Mapuche0.105048See
ENGEngland pop 619.80.1020177See
POLPoland DKMS0.101120653See
HRVCroatia Krk Island0.0990212See
DEUGermany pop 60.09828862See
HRVCroatia pop 40.09794000See
DEUGermany DKMS - Bosnia and Herzegovina minority0.09731028See
DEUGermany DKMS - German donors0.09653456066See
RUSRussia Bering Island Aleuts0.0962104See
POLPoland Wielkopolska Region0.096099See
USAUSA Caucasian Bethesda17.90.0960307See
SWESweden Northern Sami0.0950154See
DEUGermany DKMS - France minority0.09501406See
DEUGermany DKMS - Croatia minority0.09442057See
JPNJapan Hyogo18.80.094032See
JPNJapan pop 617.80.0933129See
USAUSA Eastern European0.0930558See
ENGEngland Bedfordshire17.50.0917354See
RUSRussia Tuva pop30.091044See
USAUSA Caucasian Pittsburgh18.00.0900177See
CHESwitzerland Basel0.08961888See
DEUGermany pop 80.089039689See
FRAFrance Southeast16.90.0890130See
PRTAzores Central Islands0.089059See
GEOGeorgia Caucasus Tbilisi0.0882119See
RUSRussia Northwest Slavic0.0880200See
USAUSA Caucasian pop 40.08651070See
USAUSA NMDP European Caucasian0.08601242890See
DEUGermany DKMS - Romania minority0.08551234See
CHESwitzerland Sion0.0854832See
CHESwitzerland Bern0.08523545See
CHESwitzerland Zurich0.08514875See
COLColombia Bogota and Medellin Mestizo0.085065See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.08503830See
ESPSpain Northwest Lugo15.80.0823145See
MKDMacedonia pop 10.0820158See
CHESwitzerland Geneva pop 20.08151267See
CPVCape Verde Northwestern Islands0.081062See
CZECzech Republic NMDR0.08065099See
USAUSA Minnesota Olmsted0.0800339See
DEUGermany pop 315.30.0796111See
DEUGermany DKMS - Austria minority0.07951698See
DEUGermany DKMS - United Kingdom minority0.07961043See
NIRIreland Northern15.40.07901000See
FRAFrance French Bone Marrow Donor Registry0.078742623See
ESPSpain Granada0.0780280See
MNGMongolia Tarialan Khoton0.078085See
MNGMongolia Hoton0.078085See
USAUSA Philadelphia Caucasian15.60.0780141See
CHESwitzerland Aargau-Solothurn0.07771838See
CHESwitzerland Lausanne0.0773993See
COLColombia Barranquilla0.0770188See
INDIndia Northeast Rastogi0.0770196See
CZECzech Republic0.0760106See
SWESweden Southern Sami0.0760130See
ZAFSouth Africa Caucasians0.0750102See
ESPSpain Murcia0.0750173See
CHESwitzerland Lugano0.07501169See
IRNIran Kurd pop 20.075060See
KORSouth Korea pop 214.00.0750207See
JPNJapan South14.40.0748125See
ITAItaly pop 414.20.07404575See
JPNJapan Hyogo Osaka and Nagano0.0740195See
USAUSA Caucasian pop 50.0730268See
USAUSA Mexican American Mestizo pop 30.0730116See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,14.10.07234335See
IRNIran Yazd0.071456See
KORSouth Korea pop 110.0710149See
CHNChina Yunnan Province Lahu0.071070See
CHESwitzerland Graubunden0.0704759See
USAUSA NMDP North American Amerindian0.070335791See
USAUSA San Francisco Caucasian0.0700220See
IRLIreland South13.20.0700250See
FRAFrance Rennes0.0700200See
FRAFrance Rennes pop 30.0700200See
IRNIran Yazd Zoroastrian0.069065See
KORSouth Korea pop 30.0680485See
COLColombia Providencia Island African0.067030See
USAUSA NMDP American Indian South or Central America0.06705926See
IRNIran Saqqez-Baneh Kurds0.066760See
CHESwitzerland St Gallen0.06612113See
RUSRussia Siberia Khanty Mansi0.066068See
GRCGreece Crete0.0660135See
CHESwitzerland Luzern0.06551553See
CHNChina Xinjiang Province Uyghur0.065092See
DEUGermany DKMS - Spain minority0.06501107See
KORSouth Korea pop 60.0650800See
JPNJapan pop 412.60.0650525See
JPNJapan Central0.0650371See
PRTPortugal North0.065046See
JPNJapan pop 170.06483078See
KORSouth Korea pop 100.06484128See
ESPSpain Las Alpujarras0.064785See
ITAItaly pop 50.0640975See
PRTAzores Oriental Islands0.064043See
USAUSA San Diego12.30.0630496See
KORSouth Korea pop 10.0630324See
IRNIran Gorgan0.063064See
DEUGermany DKMS - Portugal minority0.06251176See
IRNIran Fars Parsi0.062073See
CUBCuba Mixed0.061078See
CRICosta Rica Central Valley Mestizo (G)12.20.0610221See
BRABrazil Southeast Mixed Race11.90.060042See
ITAItaly Rome12.00.0600100See
ITAItaly Bergamo11.90.0600101See
COLColombia Antioquia Paisa0.0590100See
USAUSA NMDP Japanese0.058424582See
JPNJapan pop 160.058218604See
JPNJapan pop 1111.30.058162See
ITAItaly Central0.0580380See
INDIndia Northeast Vaish0.0580198See
BRABrazil Southeast Caucasian11.60.0580103See
PRTAzores Terceira Island0.0580130See
USAUSA NMDP Korean0.057877584See
BRABrazil Paraná Caucasian11.40.0577641See
ESPSpain Barcelona11.30.0570941See
PRTPortugal Azores Terceira Island10.50.0570130See
GRCGreece pop311.00.0566246See
JPNJapan pop 30.05601018See
ESPSpain Andalusia0.056099See
ARGArgentina Buenos Aires11.10.0560466See
MKDMacedonia pop 20.056080See
USAUSA NMDP Alaska Native or Aleut0.05501376See
IRNIran pop 30.0550100See
DEUGermany DKMS - Italy minority0.05441159See
ESPSpain Catalonia Girona0.054088See
JPNJapan Aichi10.90.054050See
KORSouth Korea pop 410.40.0534211See
ECUEcuadorean Amerindians0.053375See
SCOScotland Orkney10.60.053099See
DEUGermany DKMS - Greece minority0.05211894See
BRABrazil North East Mixed0.0520205See
MKDMacedonia pop 30.0520172See
PRTMadeira pop 20.0520173See
MEXMexico Chihuahua Chihuahua City Pop 210.20.051188See
PRTPortugal South0.051049See
RUSRussia Bashkortostan, Bashkirs10.00.0500120See
RUSRussia Siberia Sulamai Ket0.050022See
TUNTunisia pop 20.0500111See
IRNIran pop 20.0500120See
BRABrazil Mixed0.0500108See
COLColombia West Cauca0.050020See
USAUSA NMDP Caribean Hispanic0.0492115374See
LBNLebanon pop 20.0490191See
GRCGreece pop 89.60.048283See
INDIndia Northeast Mathur0.0480155See
JPNJapan pop 20.0480916See
JPNJapan Kyoto and Osaka0.0480165See
ESPSpain Pas Valley0.048088See
TUNTunisia Jerba Berber0.048055See
STPSao Tome Island Angolar0.047032See
BRABrazil Mato Grosso do Sul0.0470203See
IRNIran Tabriz Azeris0.046497See
ITAItaly North pop 39.30.046097See
DEUGermany DKMS - Turkey minority0.04604856See
CRICosta Rica Guanacaste Mestizo (G)9.20.0460110See
TURTurkey pop 10.0460250See
RUSRussia Tuva Todja0.045022See
ARMArmenia combined Regions0.0450100See
GRCGreece pop28.90.0450120See
USAUSA NMDP Middle Eastern or North Coast of Africa0.044970890See
USAUSA NMDP Hispanic South or Central American0.0444146714See
ESPSpain Tenerife Island0.044083See
USAUSA NMDP Mexican or Chicano0.0433261235See
USAUSA NMDP Caribean Indian0.043014339See
LBNLebanon Kafar Zubian0.043094See
ESPSpain North Cantabria0.042083See
CHNChina Harbin Korean0.0420201See
USAUSA African American Bethesda8.40.0420187See
BRABrazil South Caucasian0.041773See
COLColombia Bogotá Cord Blood7.90.04031463See
RUSRussia Siberia Khabarovsk Evenki0.040025See
GRCGreece pop 60.0393242See
USAUSA Hispanic pop 20.03881999See
GEOGeorgia Svaneti Region Svan0.038080See
ISRIsrael Ashkenazi Jews0.038080See
JORJordan Amman0.0380146See
CHNChina Lijiang Naxi0.0370100See
USAUSA Colorado Univ Cord Blood Bank Asian0.0360100See
MYSMalaysia Kelantan7.10.036028See
CHNChina Urumqi Kazak0.036042See
JPNJapan Hokkaido Wajin7.00.035671See
ARGArgentina Rosario Toba7.00.035086See
CHNChina Harbin Manchu0.0350172See
MNGMongolia Tsaatan0.0350144See
RUSRussia Siberia Irkutsk Tofalar0.035043See
ZAFSouth Africa Worcester7.00.0350159See
MEXMexico Mexico City Tlalpan7.00.0348330See
LKASri Lanka Colombo6.90.0340714See
RUSRussia Tuva pop 20.0340169See
RUSRussia Tuva0.0330190See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.03301058See
CRICosta Rica Amerindians (G)5.80.0330125See
USAUSA NMDP South Asian Indian0.0321185391See
INDIndia Northeast Rajbanshi0.031098See
USAUSA South Texas Hispanic0.0300194See
NZLNew Zealand Maori0.0300200See
SAUSaudi Arabia5.90.029918See
CZECzech Republic Romani5.90.029934See
MNGMongolia Oold0.0290104See
RUSRussia Siberia Negidal0.029035See
NICNicaragua Managua5.40.0284339See
INDIndia North pop 20.028072See
INDIndia Andhra Pradesh Golla0.0280111See
MEXMexico Mexico City Mestizo population0.0280143See
USAUSA Southern California Mestizo5.50.027873See
USAUSA Asian pop 20.02741772See
USAUSA NMDP African American pop 20.0265416581See
CHNChina Jiangsu Province Han0.0264334See
CHNChina Beijing and Xian0.0260171See
INDIndia Northeast Kayastha0.0260190See
NICNicaragua Mestizo (G)5.20.0260155See
USAUSA African American pop 40.02602411See
IRNIran Kurd0.0250100See
MEXMexico Nuevo Leon Mestizo5.00.025040See
MNGMongolia Khalkha0.0250200See
MEXMexico Mexico City Mestizo pop 30.0250256See
MEXMexico Guanajuato and Jalisco Mestizo5.00.0250101See
CHNChina pop14.90.0250103See
COLColombia Northwest Choco0.025020See
USAUSA NMDP Southeast Asian0.024427978See
USAUSA NMDP Caribean Black0.024333328See
MNGMongolia Ulaanbaatar Khalkha0.024041See
NZLNew Zealand Polynesians with Full Ancestry4.80.024021See
CHLChile Santiago0.0233920See
CHNChina Jiangsu Han0.02303238See
ISRIsrael Arab0.0230109See
RUSRussia Transbaikal Territory Buryats5.00.0230150See
USAUSA African American pop 70.0230193See
MEXMexico Tixcacaltuyub Maya0.022467See
MEXMexico Highlands Mestizos4.40.0220160See
HRVCroatia Krk Island Dubasnica0.022023See
CODCongo Kinshasa Bantu4.40.022090See
DEUGermany DKMS - China minority0.02151282See
CHNChina Hubei Han4.20.02123732See
RUSRussia Siberia Dudinka Nganasan0.021024See
USAUSA Colorado Univ Cord Blood Bank African American0.0210261See
RUSRussia Siberia Kushun Buryat0.020025See
PRTPortugal Center0.020050See
USAUSA New Mexico Zuni0.020051See
ZWEZimbabwe Harare Shona0.0200230See
ESPSpain Arratia Valley Basque0.020083See
IDNIndonesia Singaporean0.020050See
INDIndia Tamil Nadu0.01952492See
USAUSA NMDP Hawaiian or other Pacific Islander0.019411499See
ISRIsrael USSR Jews0.019345681See
MEXMexico Mexico City Mestizo pop 20.0192234See
ISRIsrael Ashkenazi Jews pop 20.0190132See
CHNChina Marrow Donor Registry0.0190600See
CANCanada British Columbia Penutian0.019026See
NZLNew Zealand Polynesians with Admixed History3.70.019027See
TUNTunisia Matmata Berber0.019081See
USAUSA NMDP African0.018828557See
MYSMalaysia Peninsular Indian3.70.0185271See
CHNChina Urumqi Uyghur3.50.018057See
FJIFiji Viti Levu Island0.018057See
MEXMexico Veracruz Xalapa3.60.017984See
JPNJapan Nagano3.50.017657See
INDIndia Lucknow3.30.0170123See
INDIndia Northeast Lachung0.017058See
CHNChina Urumqi Han0.017059See
CHNChina Beijing Shijiazhuang Tianjian Han0.0160618See
CHNChina Yunnan Province Yao0.016066See
CPVCape Verde Southeastern Islands0.016062See
INDIndia Northeast Mech0.016063See
MEXMexico Mixtec0.016097See
MEXMexico Oaxaca Jamiltepec Mixtec0.016096See
USAUSA South Dakota Sioux0.0160101See
CHLChile Mapuche0.015466See
CHNChina, Xinjiang Uyghur Autonomous Region Kazakh3.00.015252See
CHLChile Santiago Mixed3.00.015170See
DZAAlgeria pop 23.00.0151106See
DZAAlgeria Oran0.0150100See
COLColombia Sierra Nevada de Santa Marta Kogi0.015042See
CHNChina Zhejiang Han pop 20.0150833See
KENKenya, Nyanza Province, Luo tribe3.00.0150100See
NZLNew Zealand Maori with Admixed History2.90.0140105See
USAUSA Southeast African American2.70.0130112See
ISRIsrael Yemenite Jews0.013076See
IDNIndonesia Java Western2.50.0130236See
GNQEquatorial Guinea Bioko Island Bubi0.0130100See
CHNChina Yunnan Hani0.0130150See
CHNChina, Xinjiang Uyghur Autonomous Region Han2.50.012570See
BRABrazil Guarani Nandeva0.012086See
RWARwanda Kigali Hutu and Tutsi0.0110281See
SENSenegal Dakar2.20.0110112See
COLColombia North Chimila Amerindians0.010647See
ISRIsrael Georgia Jews0.01024471See
IRNIran Azeri0.0100100See
INDIndia Uttar Pradesh0.0100202See
MARMorocco Settat Chaouya0.010098See
MARMorocco Atlantic Coast Chaouya0.010098See
CHNChina Harbin Manchu pop 20.010050See
COKCook Islands0.010050See
AUSAustralia Cape York Peninsula Aborigine0.0100103See
BRABrazil Puyanawa2.00.0100150See
CHNChina Yunnan Province Han0.0100101See
THAThailand Bangkok pop 20.010050See
PERPeru Titikaka Lake Uros0.0100105See
WSMWestern Samoa and Tokelau0.010051See
AREUnited Arab Emirates Abu Dhabi0.009652See
COLColombia North Wiwa El Encanto0.009652See
USAUSA NMDP Chinese0.009399672See
SGPSingapore Riau Malay0.0090132See
PERPeru Titikaka Lake Uro0.0090105See
RUSRussia Siberia Eskimo0.009070See
GAZGaza Palestinians0.0090165See
ARGArgentina Chiriguano1.80.009054See
BRABrazil Terena1.70.009060See
IDNIndonesia Java0.009058See
GABGabon Haut-Ogooue Dienga0.0090167See
ISRIsrael Kavkazi Jews0.00852840See
MEXMexico Sinaloa Capomos Mayo Yoremes0.008360See
CANCanada British Columbia Athabaskan0.008062See
CHNChina Wuhan1.70.0080121See
COLColombia Sierra Nevada de Santa Marta Arhuaco0.0080107See
RUSRussia Siberia Chukchi0.008071See
NCLNew Caledonia0.008065See
STPSao Tome Island Forro0.008066See
ISRIsrael Poland Jews0.007813871See
ISRIsrael USA Jews0.00776058See
ISRIsrael Ashkenazi Jews pop 30.00764625See
GTMGuatemala Mayan0.0070132See
IDNIndonesia Java Yogyakarta Region0.007062See
MEXMexico Mazatecan0.007089See
USAUSA NMDP Filipino0.006750614See
HKGHong Kong Chinese cord blood registry0.00633892See
ISRIsrael Argentina Jews0.00624307See
LBNLebanon Yuhmur0.006082See
COKCook Islands Rarotonga0.006078See
CAFCentral African Republic Aka Pygmy1.20.006093See
TWNTaiwan Tzu Chi Cord Blood Bank0.0060710See
PERPeru Lamas City Lama0.006083See
ISRIsrael Arab pop 20.005812301See
TWNTaiwan Tzu Chi Morrow Donor Registry0.005446682See
MYSMalaysia Peninsular Malay1.00.0053951See
MYSMalaysia Peninsular Chinese1.00.0052194See
MNGMongolia Khalkha pop 20.0050202See
TUNTunisia pop 30.0050104See
TWNTaiwan Han Chinese0.0050504See
SAUSaudi Arabia Guraiat and Hail1.00.0050213See
TWNTaiwan Minnan pop 11.00.0050102See
USAUSA Philippines0.0050105See
ISRIsrael Iranian Jews0.0050101See
ISRIsrael Moroccan Jews0.0050113See
INDIndia Delhi0.0050112See
MARMorocco Souss Region0.005098See
CRICosta Rica African -Caribbean (G)1.00.0050102See
ISRIsrael Morocco Jews0.004936718See
GMBGambia pop 31.00.0049939See
HKGHong Kong Chinese BMDR0.00487595See
MEXMexico Chiapas Lacandon Mayans0.0046218See
RUSRussian Federation Vologda Region0.80.0042119See
USAUSA Alaska Yupik0.0040252See
ISRIsrael Ethiopian Jews0.0040122See
ESPSpain North Cabuerniga0.004095See
ARGArgentina Gran Chaco Eastern Toba0.0040135See
CHNChina Hong Kong and Singapore0.0040135See
CHNChina Wanwei, Wutou and Shanxin Islands Jing0.0040138See
CHNChina Canton Han0.0040264See
ISRIsrael YemenJews0.003615542See
TZATanzania Maasai0.60.0031336See
MEXMexico Mayan pop 20.0030163See
ISRIsrael Iran Jews0.00308153See
ISRIsrael Druze0.00305914See
USAUSA NMDP Vietnamese0.002843540See
ISRIsrael Tunisia Jews0.00239070See
TWNTaiwan pop 20.0020364See
USAUSA South Dakota Lakota Sioux0.0020302See
ISRIsrael Bukhara Jews0.00172317See
ISRIsrael Libya Jews0.00163739See
ISRIsrael Iraq Jews0.001513270See
ISRIsrael Ethiopia Jews0.00025928See
ISRIsrael Libyan Jews0.0000119See
GNBGuinea Bissau0.000065See
IDNIndonesia Nusa Tenggara Islands0.000049See
IDNIndonesia Moluccan Islands0.000024See
MARMorocco Nador Metalsa0.000099See
LBNLebanon Niha el Shouff0.000061See
CHNChina Yunnan Province Drung0.000070See
CHNChina Guizhou Province Miao0.000085See
ARGArgentina Gran Chaco Mataco Wichi0.000049See
ARGArgentina Gran Chaco Western Toba Pilaga0.000019See
BRABrazil Kaingang0.0000235See
BRABrazil Guarani M bya0.000093See
BORBorneo Bandjarmasin0.000021See
BRABrazil East Amazon0.000041See
BRABrazil Central Plateau Xavante0.000074See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
WSMSamoa West0.000022See
WSMSamoa pop20.000050See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Aborigine pop 20.000048See
TUNTunisia Gabes Arab0.000096See
THAThailand North Dai Lue0.000096See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
SDNSudan Mixed0.00.0000200See
RUSRussia Siberia North East Kamchatka Koryak0.000092See
RUSRussia Siberia Gvaysugi Udege0.000025See
RUSRussia Siberia NW of Sakhalin Island Nivkh0.000032See
RUSRussia Siberia Chukotka Peninsula Chukchi0.000059See
RUSRussia Siberia Chukotka Peninsula Eskimo0.000080See
RUSRussia Siberia Ulchi0.000073See
RUSRussia Siberia Lower Yenisey Ket0.000017See
PRYParaguay Aché0.000087See
PHLPhilippines Ivatan0.00.000050See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PNGPapua New Guinea Lowland Roro0.000026See
PNGPapua New Guinea Trobriand Island0.000081See
PNGPapua New Guinea Lowland0.000047See
PNGPapua New Guinea Lowland Wosera0.000079See
PNGPapua New Guinea Highland0.000094See
PNGPapua New Guinea East New Britain Tolai0.000048See
PNGPapua New Guinea Highland pop20.000028See
PERPeru Quechua0.000044See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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