Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.



Allele reported 178 time(s) and present in 165 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CAFCentral African Republic Mbenzele Pygmy77.00.520436See
CMRCameroon Baka Pygmy0.250010See
USAUSA Alaska Yupik0.2440252See
CMRCameroon Sawa0.192013See
CMRCameroon Bamileke0.110077See
DEUGermany Essen20.10.1030174See
KENKenya Luo0.1000265See
ZMBZambia Lusaka0.100044See
USAUSA African American0.0970252See
PRTPortugal Center pop 20.0930562See
UGAUganda Kampala0.0920161See
USAUSA African American Bethesda17.00.0900187See
USAUSA NMDP African American pop 20.0890416581See
USAUSA NMDP Alaska Native or Aleut0.08801376See
KENKenya Nandi0.0880240See
BRABrazil Puyanawa17.30.0870150See
DEUGermany DKMS - Bosnia and Herzegovina minority0.08511028See
USAUSA NMDP African0.084728557See
USAUSA African American pop 40.08462411See
ZWEZimbabwe Harare Shona0.0820230See
DEUGermany DKMS - Croatia minority0.08152057See
USAUSA NMDP Caribean Black0.080733328See
GRCGreece pop 815.70.078383See
PRTAzores Terceira Island0.0780130See
USAUSA North American Native0.0780187See
POLPoland DKMS0.076120653See
GHAGhana Ga-Adangbe13.70.0725131See
SENSenegal Niokholo Mandenka0.0710165See
GRCGreece pop 60.0702242See
ZAFSouth Africa Caucasians0.0690102See
DEUGermany DKMS - Romania minority0.06771234See
FRAFrance West13.00.0672100See
ISRIsrael Arab Druze0.0650101See
USAUSA NMDP Caribean Indian0.064014339See
RUSRussia Karelia0.06241075See
USAUSA NMDP Caribean Hispanic0.0624115374See
DEUGermany DKMS - Portugal minority0.06231176See
CHESwitzerland Graubunden0.0598759See
CHESwitzerland Sion0.0594832See
RUSRussia North Ossetian11.00.0591127See
USAUSA Arizona Gila River Amerindian0.0590492See
CZECzech Republic NMDR0.05775099See
PRTPortugal Azores Terceira Island11.40.0570130See
DEUGermany DKMS - German donors0.05633456066See
DEUGermany DKMS - Netherlands minority0.05621374See
DEUGermany DKMS - Greece minority0.05581894See
CHESwitzerland Basel0.05571888See
USAUSA NMDP North American Amerindian0.055435791See
ITAItaly Sardinia pop30.0550100See
DEUGermany DKMS - Austria minority0.05451698See
DEUGermany pop 80.054139689See
MLIMali Bandiagara0.0540138See
DEUGermany pop 60.05398862See
RUSRussia Bering Island Aleuts0.0529104See
DEUGermany DKMS - Spain minority0.05151107See
DEUGermany DKMS - France minority0.05091406See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,9.90.05094335See
CHESwitzerland Lausanne0.0506993See
ESPSpain Sevilla10.10.0504278See
RUSRussia Murmansk Saomi Mixed0.050070See
CHESwitzerland St Gallen0.04912113See
ESPSpain Andalusia0.049099See
MKDMacedonia pop 40.0490216See
CMRCameroon Beti0.0460174See
USAUSA San Francisco Caucasian0.0460220See
USAUSA Caucasian Bethesda9.10.0450307See
CHESwitzerland Geneva pop 20.04501267See
ESPSpain Andalusia Romani0.045099See
CHESwitzerland Luzern0.04451553See
CHESwitzerland Bern0.04433545See
CHESwitzerland Geneva0.044080See
CHESwitzerland Lugano0.04361169See
USAUSA NMDP European Caucasian0.04351242890See
DEUGermany DKMS - United Kingdom minority0.04311043See
NLDNetherlands Leiden0.04301305See
USAUSA NMDP American Indian South or Central America0.04305926See
USAUSA Hispanic pop 20.04231999See
ITAItaly pop 50.0420975See
JORJordan Amman0.0410146See
USAUSA Philadelphia Caucasian7.10.0410141See
CHESwitzerland Zurich0.04074875See
RUSRussia Arkhangelsk Pomor0.040063See
CHESwitzerland Aargau-Solothurn0.03951838See
DEUGermany DKMS - Italy minority0.03941159See
NLDNetherlands UMCU7.80.039164See
COLColombia Bogotá Cord Blood7.40.03761463See
USAUSA Caucasian pop 40.03741070See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0370146See
USAUSA NMDP Hispanic South or Central American0.0367146714See
IRNIran Tehran0.0360120See
IRLIreland South7.20.0360250See
USAUSA San Diego6.70.0350496See
USAUSA NMDP Middle Eastern or North Coast of Africa0.034870890See
DEUGermany DKMS - Turkey minority0.03464856See
USAUSA South Texas Hispanic0.0340194See
USAUSA Hispanic0.0340234See
USAUSA NMDP Mexican or Chicano0.0336261235See
USAUSA Caucasian pop 20.0320265See
ITAItaly South0.0320141See
FRAFrance Southeast6.20.0310130See
AREUnited Arab Emirates Abu Dhabi0.028852See
GBRUnited Kingdom pop 35.60.0280604See
ESPSpain Majorca and Minorca0.028090See
ZAFSouth Africa Worcester6.00.0280159See
ITAItaly North0.0270277See
NICNicaragua Managua5.10.0256339See
CHLChile Santiago Mixed5.00.025370See
IRNIran Gorgan0.023464See
RUSRussia Transbaikal Territory Buryats5.00.0230150See
NIRIreland Northern4.10.02101000See
CHNChina Wuhan4.20.0210121See
FRAFrance Corsica Island0.0200100See
SCOScotland Orkney3.90.019099See
USAUSA San Antonio Caucasian0.0182222See
INDIndia Central UCBB3.30.01644204See
INDIndia East UCBB3.10.01562403See
CHNChina Sichuan HIV negative0.015034See
CHNChina North Han pop 20.0150567See
CHNChina Yunnan Province Han0.0150101See
INDIndia North UCBB2.90.01445849See
TZATanzania Maasai2.20.0141336See
SAUSaudi Arabia Guraiat and Hail2.80.0140213See
MEXMexico Mexico City Mestizo pop 20.0128234See
INDIndia West UCBB2.40.01225829See
INDIndia Delhi pop 22.50.012090See
RUSRussia Nenet Mixed0.012055See
USAUSA NMDP South Asian Indian0.0093185391See
GEOGeorgia Tibilisi0.0090109See
BRABrazil Mixed0.0090108See
USAUSA NMDP Southeast Asian0.008127978See
KORSouth Korea pop 30.0080485See
DEUGermany DKMS - China minority0.00781282See
MYSMalaysia Peninsular Indian1.50.0074271See
MEXMexico Mexico City Mestizo population0.0070143See
PNGPapua New Guinea Wanigela Keapara0.007066See
USAUSA NMDP Korean0.007077584See
USAUSA NMDP Hawaiian or other Pacific Islander0.006411499See
INDIndia South UCBB1.30.006311446See
AUSAustralia Cape York Peninsula Aborigine0.0060103See
INDIndia Tamil Nadu0.00582492See
INDIndia Northeast UCBB1.00.0051296See
CHNChina Marrow Donor Registry0.0050600See
KENKenya, Nyanza Province, Luo tribe1.00.0050100See
SGPSingapore SGVP Chinese CHS0.005096See
LKASri Lanka Colombo1.00.0050714See
CHNChina South Han pop 20.00411098See
CHNChina Southwest Dai0.0040124See
USAUSA Asian pop 20.00401772See
USAUSA NMDP Chinese0.003699672See
USAUSA Asian0.0030358See
CHNChina Hubei Han0.60.00293732See
USAUSA NMDP Filipino0.002950614See
HKGHong Kong Chinese BMDR0.00287595See
MYSMalaysia Peninsular Malay0.40.0021951See
TWNTaiwan Han Chinese0.0020504See
USAUSA NMDP Vietnamese0.001843540See
USAUSA NMDP Japanese0.001524582See
JPNJapan pop 160.000318604See
ITAItaly North pop 30.00.000097See
CHNChina Inner Mongolia Region0.0000102See
CHNChina Tibet Region Tibetan0.0000158See
CHNChina North Han0.0000105See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
NCLNew Caledonia0.000065See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See
SGPSingapore SGVP. Indian INS0.000086See
SGPSingapore SGVP Malay MAS0.000089See

See also higher resolution data of this allele

Allele  Number of Populations 
 C*02:02:01 35 
 C*02:02:02 84 
 C*02:02:03 22 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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