Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.

Allele: 
   

DRB1*04:01

 
Allele reported 422 time(s) and present in 354 population(s).

Population Phenotype
Frequency (%)
Allele
Frequency
(in_decimals)
Sample
Size
IMGT/HLA¹
Database
Distribution² Haplotype³
Association
Notesª
RUSRussia Siberia Eskimo0.361070See
RUSRussia Siberia Chukotka Peninsula Chukchi0.300059See
RUSRussia Siberia Chukotka Peninsula Eskimo0.280080See
RUSRussia Siberia Chukchi0.254071See
USAUSA Alaska Yupik0.2320252See
RUSRussia Siberia North East Kamchatka Koryak0.210092See
JORJordan Amman0.1970146See
COLColombia Barranquilla0.1860188See
DNKDenmark0.176055See
TUNTunisia pop 20.1700111See
LBNLebanon pop 20.1640191See
IRNIran Tabriz Azeris0.154697See
RUSRussia Vologda0.1410121See
NORNorway0.1400181See
ENGEngland Bedfordshire25.10.1345354See
BLRBelarus Brest Region0.1280105See
NLDNetherlands UMCU23.40.125064See
IRNIran Saqqez-Baneh Kurds0.125060See
IRNIran Kurd pop 20.125060See
ENGEngland pop 622.60.1240177See
FRAFrance South0.1230350See
RUSRussia Siberia Negidal0.114035See
USAUSA NMDP Alaska Native or Aleut0.11401376See
UKRUkraine Lvov0.1130102See
UKRUkraine Khmelnytskyi0.1120138See
ZAFSouth Africa Caucasians0.1120102See
SWESweden Southern Sami0.1120130See
USAUSA Caucasian pop 50.1100268See
FRAFrance Rennes pop 30.1100200See
IRNIran Gorgan0.109064See
USAUSA San Antonio Caucasian0.1081222See
DEUGermany DKMS - United Kingdom minority0.10741043See
MNGMongolia Ulaanbaatar Khalkha0.105041See
MNGMongolia Tsaatan0.1040144See
USAUSA Caucasian pop 40.10391070See
SCOScotland Orkney20.20.103099See
IRLIreland South20.00.1020250See
FRAFrance Rennes0.1000200See
BLRBelarus Gomel Region0.1000100See
IRNIran Yazd0.098256See
NLDNetherlands Leiden0.09701305See
DEUGermany pop 318.00.0944111See
ZAFSouth Africa Worcester19.00.0940159See
RUSRussia Mari0.0940202See
DEUGermany DKMS - Netherlands minority0.09211374See
USAUSA Minnesota Olmsted0.0910339See
USAUSA Caucasian17.30.090661655See
RUSRussia Siberia Polygus Evenk0.090035See
RUSRussia Siberia Gvaysugi Udege0.090025See
USAUSA NMDP European Caucasian0.08781242890See
RUSRussia Bering Island Aleuts0.0865104See
USAUSA Caucasian Houston16.00.0860194See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.08603830See
USAUSA Caucasian Pittsburgh16.80.0840177See
FINFinland0.083091See
COLColombia Providencia Island African0.083030See
DEUGermany DKMS - German donors0.08163456066See
MNGMongolia Tarialan Khoton0.081085See
DEUGermany pop 60.08098862See
MNGMongolia Hoton0.080085See
RUSRussia Transbaikal Territory Buryats15.00.0800150See
RUSRussia Siberia Kushun Buryat0.080025See
DEUGermany Essen14.90.0750174See
BLRBelarus Vitebsk Region0.075070See
USAUSA Caucasian Bethesda13.80.0720307See
FINFinland pop20.0700150See
DEUGermany pop 80.068439689See
AUTAustria13.50.0680200See
USAUSA Eastern European0.0680558See
USAUSA San Francisco Caucasian0.0680220See
FRAFrance West13.00.0672100See
CZECzech Republic0.0670106See
MNGMongolia Oold0.0670104See
DEUGermany DKMS - Austria minority0.06631698See
USAUSA NMDP American Indian South or Central America0.06605926See
USAUSA NMDP North American Amerindian0.065835791See
PRTPortugal North0.065046See
FRAFrance French Bone Marrow Donor Registry0.064742623See
ESPSpain Las Alpujarras0.064785See
USAUSA Philadelphia Caucasian12.80.0640141See
SVNSlovenia12.00.0619100See
NLDNetherlands11.90.0613447See
BELBelgium12.10.061099See
MNGMongolia Khalkha0.0600200See
RUSRussia Northwest Slavic0.0600200See
CZECzech Republic NMDR0.05915099See
FRAFrance Southeast11.50.0590130See
RUSRussia Siberia Irkutsk Tofalar0.058043See
RUSRussia Tuva pop30.057044See
DEUGermany DKMS - France minority0.05691406See
IRNIran pop 20.0542120See
POLPoland DKMS0.053420653See
RUSRussia Tuva pop 20.0530169See
ESPSpain Northwest Lugo10.30.0529145See
SWESweden Northern Sami0.0510154See
PRTPortugal South0.051049See
NZLNew Zealand Maori0.0500200See
MNGMongolia Khalkha pop 20.0500202See
RUSRussia Karelia0.04981075See
RUSRussia Tuva0.0480190See
CHNChina, Xinjiang Uyghur Autonomous Region Kazakh9.10.045552See
ARMArmenia combined Regions0.0450100See
CZECzech Republic Romani8.80.045034See
PRTAzores Central Islands0.045059See
RUSRussia Tuva Todja0.045022See
NZLNew Zealand Maori with Admixed History8.60.0430105See
DEUGermany DKMS - Romania minority0.04301234See
ITAItaly Bergamo7.90.0410101See
RUSRussia Siberia Ulchi0.041073See
USAUSA San Diego7.90.0410496See
ESPSpain Pas Valley0.038088See
LBNLebanon Kafar Zubian0.038094See
PRTAzores Oriental Islands0.038043See
PNGPapua New Guinea Lowland Roro0.038026See
DEUGermany DKMS - Spain minority0.03731107See
NRUNauru0.037067See
CZECzech Republic pop 27.10.036199See
ESPSpain North Cantabria0.036083See
ESPSpain Murcia0.0360173See
USAUSA African American Bethesda5.60.0350187See
BRABrazil Mixed0.0350108See
POLPoland Wielkopolska Region0.035099See
JAMJamaica0.0340132See
INDIndia Northeast Lachung0.034058See
NZLNew Zealand Maori with Full Ancestry6.50.033046See
DEUGermany DKMS - Bosnia and Herzegovina minority0.03261028See
DEUGermany DKMS - Portugal minority0.03231176See
INDIndia Northeast Mech0.032063See
DEUGermany DKMS - Croatia minority0.03182057See
INDIndia Northeast Rajbanshi0.031098See
NCLNew Caledonia0.031065See
MTQMartinique0.0300100See
ITAItaly North pop 34.10.030097See
IRNIran pop 30.0300100See
HRVCroatia pop 40.02964000See
CHNChina, Xinjiang Uyghur Autonomous Region Hui5.90.029440See
ARGArgentina Buenos Aires5.80.0290466See
SVNSlovenia pop 25.70.0289140See
MYSMalaysia Peninsular Indian5.50.0277271See
CHNChina Xinjiang Province Uyghur0.027092See
ESPSpain Granada0.0270280See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,5.20.02644335See
TUNTunisia Gabes0.026395See
TUNTunisia Gabes Arab0.026096See
COKCook Islands Rarotonga0.026078See
USAUSA NMDP Middle Eastern or North Coast of Africa0.025470890See
USAUSA Colorado Univ Cord Blood Bank African American0.0250261See
CHNChina, Xinjiang Uyghur Autonomous Region Han5.00.025070See
BRABrazil North East Mixed0.0250205See
MEXMexico Nuevo Leon Mestizo5.00.025040See
POLPoland0.0250200See
BRABrazil Southeast Caucasian4.80.0240103See
ETHEthiopia Oromo0.024083See
USAUSA South Texas Hispanic0.0230194See
USAUSA NMDP Caribean Indian0.023014339See
STPSao Tome Island Forro0.023066See
WSMSamoa West0.023022See
USAUSA African American pop 40.02292411See
USAUSA NMDP Caribean Hispanic0.0225115374See
ISRIsrael USSR Jews0.022345681See
DEUGermany DKMS - Turkey minority0.02224856See
CHNChina Beijing and Xian0.0220171See
HRVCroatia Krk Island Dubasnica0.022023See
SAUSaudi Arabia Guraiat and Hail4.40.0220213See
PRTPortugal Azores Terceira Island4.40.0219130See
DEUGermany DKMS - Greece minority0.02171894See
CHNChina, Xinjiang Uyghur Autonomous Region Uyghur4.40.021471See
BRABrazil Paraná Caucasian4.10.0211641See
GEOGeorgia Caucasus Tbilisi0.0210119See
ISRIsrael Ethiopian Jews0.0210122See
RUSRussia Siberia Dudinka Nganasan0.021024See
ESPSpain North Cabuerniga0.021095See
USAUSA NMDP African American pop 20.0202416581See
TURTurkey pop 10.0200250See
USAUSA Colorado Univ Cord Blood Bank Asian0.0200100See
ESPSpain Arratia Valley Basque0.020083See
ESPSpain Andalusia0.020099See
ESPSpain Barcelona4.00.0200941See
ITAItaly Rome4.00.0200100See
ITAItaly Central0.0200380See
JPNJapan0.020050See
PRTAzores Terceira Island0.0200130See
PRTPortugal Center0.020050See
RUSRussia Siberia Sulamai Ket0.020022See
MYSMalaysia Patani4.00.020025See
ECUEcuadorean Amerindians0.020075See
GRCGreece pop 40.020098See
CHNChina pop13.90.0200103See
DEUGermany DKMS - Italy minority0.01941159See
GEOGeorgia Svaneti Region Svan0.019080See
MKDMacedonia pop 20.019080See
NZLNew Zealand Polynesians with Admixed History3.70.019027See
ISRIsrael Ashkenazi Jews pop 20.0190132See
ISRIsrael Ethiopia Jews0.01855928See
USAUSA NMDP Mexican or Chicano0.0181261235See
LKASri Lanka Colombo3.60.0180714See
JPNJapan Nagano3.50.017657See
PANPanama0.0175462See
USAUSA NMDP Hawaiian or other Pacific Islander0.017111499See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.01701058See
PRTMadeira pop 20.0170173See
ITAItaly pop 50.0170975See
CHNChina Urumqi Han0.017059See
INDIndia Northeast Kayastha0.0160190See
JPNJapan Hyogo3.10.016032See
JPNJapan pop 43.20.0160525See
STPSao Tome Island Angolar0.016032See
MEXMexico Mexico City Tlalpan3.00.0152330See
CUBCuba Mixed0.015078See
RUSRussia Siberia Khanty Mansi0.015068See
USAUSA NMDP Hispanic South or Central American0.0150146714See
USAUSA Hispanic pop 20.01451999See
BOLBolivia Quechua0.014569See
BRABrazil South Caucasian0.013973See
USAUSA NMDP Caribean Black0.013633328See
USAUSA NMDP African0.013528557See
USAUSA Hawaii0.013039See
USAUSA African American pop 70.0130193See
INDIndia Northeast Mathur0.0130155See
JPNJapan pop 30.01301018See
MKDMacedonia pop 10.0130158See
INDIndia Northeast Shia0.0130190See
ISRIsrael USA Jews0.01306058See
CHNChina Jiangsu Province Han0.0122334See
GRCGreece pop 82.40.012183See
GAZGaza Palestinians0.0120165See
CHNChina Marrow Donor Registry0.0120600See
CHNChina Urumqi Kazak0.012042See
CHNChina Beijing Shijiazhuang Tianjian Han0.0120618See
CHNChina Harbin Korean0.0120201See
BRABrazil Mato Grosso do Sul0.0120203See
JPNJapan pop 20.0120916See
MKDMacedonia pop 30.0120172See
NICNicaragua Managua2.40.0120339See
TUNTunisia Matmata Berber0.012081See
RUSRussia Chuvash0.012082See
DEUGermany DKMS - China minority0.01171282See
COLColombia Bogotá Cord Blood2.30.01161463See
USAUSA NMDP Japanese0.011524582See
INDIndia North2.30.011585See
MEXMexico Chihuahua Chihuahua City Pop 22.30.011488See
PNGPapua New Guinea Highland0.011094See
CODCongo Kinshasa Bantu2.20.011090See
CODCongo Kinshasa expatriates living in Belgium2.30.011075See
CHLChile Santiago0.0108920See
TZATanzania Maasai2.10.0107336See
ISRIsrael Georgia Jews0.01064471See
MEXMexico Mexico City Mestizo population0.0105143See
COLColombia Wayu from Guajira Peninsula0.010448See
GRCGreece pop 60.0103242See
GRCGreece pop32.00.0100246See
INDIndia Northeast Rastogi0.0100196See
INDIndia Northeast Vaish0.0100198See
ETHEthiopia Amhara0.010098See
CHNChina Harbin Manchu pop 20.010050See
CHNChina Jiangsu Han0.01003238See
BRABrazil Puyanawa2.00.0100150See
MEXMexico Guanajuato and Jalisco Mestizo2.00.0100101See
MARMorocco Settat Chaouya0.010098See
MARMorocco Atlantic Coast Chaouya0.010098See
WSMWestern Samoa and Tokelau0.010051See
USAUSA South Dakota Lakota Sioux0.0100302See
USAUSA South Dakota Sioux0.0100101See
INDIndia Tamil Nadu0.00952492See
JPNJapan pop 160.009518604See
ISRIsrael Ashkenazi Jews pop 30.00914625See
JPNJapan pop 170.00913078See
LBNLebanon Niha el Shouff0.009061See
ISRIsrael Arab0.0090109See
INDIndia North pop 20.009072See
ARGArgentina Chiriguano1.80.009054See
CHNChina Urumqi Uyghur1.80.009057See
CHNChina Harbin Manchu0.0090172See
COLColombia Guajira Peninsula Wayuu0.009088See
USAUSA Southeast African American1.80.0090112See
USAUSA Asian pop 20.00911772See
USAUSA NMDP South Asian Indian0.0090185391See
KOSKosovo1.60.0081124See
ISRIsrael Libyan Jews0.0080119See
INDIndia Northeast Sunni0.0080188See
KORSouth Korea pop 60.0080800See
JPNJapan pop 111.60.008062See
CHNChina Wuhan1.70.0080121See
CHNChina Yunnan Province Han pop 20.0080129See
BRABrazil Kaingang0.0080235See
CANCanada British Columbia Athabaskan0.008062See
GRCGreece pop21.60.0080120See
USAUSA NMDP Southeast Asian0.007827978See
USAUSA NMDP Korean0.007877584See
CHNChina Hubei Han1.50.00743732See
KORSouth Korea pop 100.00734128See
ISRIsrael YemenJews0.007215542See
KORSouth Korea pop 41.40.0070211See
KORSouth Korea pop 30.0070485See
JPNJapan Central0.0070371See
GRCGreece Crete0.0070135See
CHNChina Zhejiang Han pop 20.0066833See
MEXMexico Mexico City Mestizo pop 20.0064234See
MEXMexico Veracruz Xalapa1.20.006084See
KORSouth Korea pop 10.0060324See
ISRIsrael Non Ashkenazi Jews0.006080See
BRABrazil Guarani Nandeva0.006086See
ARGArgentina Rosario Toba1.20.006086See
TWNTaiwan Han Chinese0.0060504See
TWNTaiwan pop 20.0060364See
GMBGambia pop 31.10.0055939See
MYSMalaysia Peninsular Chinese1.00.0052194See
USAUSA NMDP Chinese0.005199672See
USAUSA Philippines0.0050105See
TUNTunisia pop 30.0050104See
THAThailand Kamphaeng Phet0.005097See
SDNSudan Mixed1.00.0050200See
RWARwanda Kigali Hutu and Tutsi0.0050281See
IRNIran Azeri0.0050100See
JPNJapan Hyogo Osaka and Nagano0.0050195See
ITAItaly Sardinia pop20.90.00501129See
INDIndia Delhi0.0050112See
DZAAlgeria0.005097See
AUSAustralia Cape York Peninsula Aborigine0.0050103See
HRVCroatia Krk Island0.0050212See
CHNChina Canton Han0.0040264See
CHNChina Yunnan Bulang0.0040116See
GRCCretan Islanders0.0040124See
JPNJapan South0.80.0040125See
JPNJapan pop 60.80.0040129See
THAThailand0.0040142See
USAUSA Mexican American Mestizo pop 30.0040116See
USAUSA NMDP Filipino0.003750614See
TWNTaiwan Tzu Chi Morrow Donor Registry0.003546682See
ISRIsrael Poland Jews0.003313871See
HKGHong Kong Chinese cord blood registry0.00313892See
JPNJapan Kyoto and Osaka0.0030165See
MEXMexico Highlands Mestizos0.60.0030160See
VNMVietnam Hanoi Kinh pop 20.0030170See
HKGHong Kong Chinese BMDR0.00257595See
USAUSA NMDP Vietnamese0.002543540See
ISRIsrael Arab pop 20.002412301See
ISRIsrael Argentina Jews0.00234307See
MYSMalaysia Peninsular Malay0.40.0021951See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0021233See
THAThailand Northeast0.002066See
TWNTaiwan Tzu Chi Cord Blood Bank0.0020710See
USAUSA Arizona Gila River Amerindian0.0020492See
INDIndia Uttar Pradesh0.0020202See
ISRIsrael Tunisia Jews0.00199070See
ISRIsrael Iraq Jews0.001913270See
ISRIsrael Kavkazi Jews0.00182840See
ISRIsrael Libya Jews0.00153739See
THAThailand Northeast pop 20.0010400See
ISRIsrael Druze0.00095914See
ISRIsrael Bukhara Jews0.00092317See
ISRIsrael Morocco Jews0.000436718See
ISRIsrael Iran Jews0.00028153See
IRNIran Kurd0.0000100See
ISRIsrael Iranian Jews0.0000101See
ISRIsrael Moroccan Jews0.0000113See
ISRIsrael Yemenite Jews0.000076See
JPNJapan Hokkaido Wajin0.00.000071See
KORSouth Korea pop 20.00.0000207See
KIRKiribati0.000062See
LBNLebanon Yuhmur0.000082See
MYSMalaysia0.000074See
MARMorocco Nador Metalsa0.000099See
NIUNiue0.000070See
RUSRussia Siberia NW of Sakhalin Island Nivkh0.000032See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PRYParaguay Lengua0.000017See
PHLPhilippines0.000034See
PHLPhilippines Ivatan0.00.000050See
PNGPapua New Guinea East New Britain Tolai0.000048See
PNGPapua New Guinea Highland pop20.000028See
PNGPapua New Guinea Trobriand Island0.000081See
PNGPapua New Guinea Lowland0.000047See
PNGPapua New Guinea Lowland Wosera0.000079See
IDNIndonesia Java0.000058See
IDNIndonesia Nusa Tenggara Islands0.000049See
IDNIndonesia Moluccan Islands0.000024See
IDNIndonesia Singaporean0.000050See
IDNIndonesia Java Yogyakarta Region0.000062See
FJIFiji Viti Levu Island0.000057See
CANCanada British Columbia Penutian0.000026See
CAFCentral African Republic Aka Pygmy0.00.000093See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
BRABrazil Central Plateau Xavante0.000074See
BRABrazil Guarani M bya0.000093See
BRABrazil Southeast Mixed Race0.00.000042See
BORBorneo Bandjarmasin0.000021See
ARGArgentina Rio Negro Mapuche0.000034See
ARGArgentina Chubut Tehuelche0.000023See
ARGArgentina Salta Wichi0.000024See
ARGArgentina Gran Chaco Eastern Toba0.0000135See
ARGArgentina Gran Chaco Mataco Wichi0.000049See
ARGArgentina Gran Chaco Western Toba Pilaga0.000019See
DZAAlgeria pop 20.00.0000106See
CHNChina Yunnan Province Naxi0.0000118See
COLColombia Bogota and Medellin Mestizo0.000065See
CHNChina Hong Kong and Singapore0.0000135See
TUNTunisia Jerba Berber0.000055See
THAThailand North Dai Lue0.000096See
TWNTaiwan Aborigine pop 20.000048See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
WSMSamoa0.000029See
RUSRussia Siberia Khabarovsk Evenki0.000025See
RUSRussia Siberia Lower Yenisey Ket0.000017See
SAUSaudi Arabia0.00.000018See
TUNTunisia0.00.0000100See

Frequency data at lower resolution for this allele can be found in links below


Allele  Number of Populations 

Notes:

* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


   

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

support@allelefrequencies.net


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