Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 471 time(s) and present in 416 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
GNQEquatorial Guinea Bioko Island Bubi0.2410100See
RUSRussia Siberia Lower Yenisey Ket0.235017See
HRVCroatia Krk Island Dubasnica0.217023See
TUNTunisia pop 20.2100111See
CAFCentral African Republic Aka Pygmy30.90.155093See
IRNIran Yazd Zoroastrian0.154065See
INDIndia Andhra Pradesh Golla0.1380111See
CHNChina, Xinjiang Uyghur Autonomous Region Kazakh27.30.136452See
ESPSpain Tenerife Island0.132083See
ZAFSouth Africa Limpopo Venda0.1280117See
RUSRussia Siberia Khanty Mansi0.125068See
GEOGeorgia Svaneti Region Svan0.125080See
HRVCroatia Krk Island0.1180212See
CZECzech Republic Romani20.60.108934See
SAUSaudi Arabia Guraiat and Hail17.90.1060213See
ESPSpain Gipuzkoa Basque0.1020100See
PRTPortugal Azores Terceira Island18.40.1009130See
PRTPortugal Center0.100050See
CRICosta Rica Central Valley Mestizo (G)19.10.1000221See
CHNChina, Xinjiang Uyghur Autonomous Region Uyghur19.60.097871See
ZAFSouth Africa Worcester18.00.0970159See
GEOGeorgia Caucasus Tbilisi0.0966119See
ESPSpain Catalonia Girona0.095088See
PRTMadeira pop 20.0950173See
ESPSpain Las Alpujarras0.094185See
SWESweden Southern Sami0.0930130See
DEUGermany Essen18.40.0920174See
RUSRussia Tuva pop30.091044See
RUSRussia Tuva Todja0.091022See
BRABrazil South Caucasian0.090373See
FINFinland pop20.0900150See
ISRIsrael Moroccan Jews0.0890113See
PRTAzores Terceira Island0.0890130See
DEUGermany DKMS - Portugal minority0.08851176See
CHNChina, Xinjiang Uyghur Autonomous Region Hui17.70.088240See
INDIndia Northeast Kayastha0.0860190See
ITAItaly pop 20.085053See
ZWEZimbabwe Harare Shona0.0850230See
DEUGermany DKMS - Spain minority0.08451107See
RUSRussia Karelia0.08411075See
ESPSpain North Cantabria0.084083See
ESPSpain Murcia0.0830173See
COLColombia Barranquilla0.0825188See
PRTPortugal South0.082049See
TUNTunisia Jerba Berber0.082055See
CHESwitzerland Graubunden0.0813759See
CZECzech Republic0.0810106See
FRAFrance Rennes pop 30.0800200See
IRNIran pop 30.0800100See
TUNTunisia Matmata Berber0.080081See
USAUSA Caucasian Houston16.00.0800194See
INDIndia Tamil Nadu0.07992492See
INDIndia Lucknow15.70.0790123See
FRAFrance Rennes0.0780200See
DEUGermany pop 80.078039689See
USAUSA African American pop 70.0780193See
DEUGermany DKMS - Romania minority0.07781234See
DEUGermany DKMS - Austria minority0.07771698See
INDIndia Uttar Pradesh0.0770202See
DEUGermany pop 60.07688862See
FRAFrance French Bone Marrow Donor Registry0.076642623See
DEUGermany DKMS - German donors0.07643456066See
ESPSpain Andalusia0.076099See
ESPSpain Pas Valley0.076088See
CZECzech Republic NMDR0.07415099See
ISRIsrael Libyan Jews0.0740119See
DEUGermany DKMS - Netherlands minority0.07391374See
CHESwitzerland Geneva pop 20.07371267See
DEUGermany DKMS - Croatia minority0.07322057See
CRICosta Rica Guanacaste Mestizo (G)14.60.0730110See
MKDMacedonia pop 10.0730158See
DEUGermany DKMS - France minority0.07261406See
CHESwitzerland Bern0.07233545See
CODCongo Kinshasa Bantu14.40.072090See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,13.80.07194335See
CHESwitzerland Luzern0.07151553See
CHNChina Xinjiang Province Uyghur0.071092See
POLPoland Wielkopolska Region0.071099See
POLPoland DKMS0.070520653See
CHESwitzerland St Gallen0.07002113See
BRABrazil Mixed0.0700108See
ESPSpain Barcelona13.70.0700941See
USAUSA NMDP Caribean Hispanic0.0698115374See
USAUSA Minnesota Olmsted0.0690339See
USAUSA NMDP Caribean Indian0.068014339See
STPSao Tome Island Forro0.068066See
LBNLebanon pop 20.0680191See
CZECzech Republic pop 213.10.067899See
CHESwitzerland Aargau-Solothurn0.06771838See
USAUSA NMDP South Asian Indian0.0673185391See
USAUSA Colorado Univ Cord Blood Bank African American0.0670261See
LKASri Lanka Colombo12.50.0670714See
RUSRussia Tuva0.0660190See
USAUSA Eastern European0.0660558See
CHESwitzerland Zurich0.06574875See
IRNIran Kurd0.0650100See
ISRIsrael Ashkenazi Jews0.065080See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.06503830See
RUSRussia Northwest Slavic0.0650200See
CHESwitzerland Lugano0.06481169See
HRVCroatia pop 40.06444000See
FRAFrance Southeast12.30.0640130See
ZAFSouth Africa Caucasians0.0640102See
PRTAzores Central Islands0.063059See
BRABrazil Southeast Caucasian12.60.0630103See
INDIndia Northeast Vaish0.0630198See
CHNChina, Xinjiang Uyghur Autonomous Region Han12.50.062570See
CHESwitzerland Basel0.06241888See
NLDNetherlands Leiden0.06201305See
SVNSlovenia pop 212.00.0619140See
DEUGermany DKMS - United Kingdom minority0.06191043See
CHESwitzerland Lausanne0.0615993See
CHNChina Urumqi Uyghur10.50.061057See
MKDMacedonia pop 20.061080See
TUNTunisia Ghannouch0.061082See
DEUGermany DKMS - Bosnia and Herzegovina minority0.06031028See
COLColombia San Basilio de Palenque0.060042See
ESPSpain Arratia Valley Basque0.060083See
BRABrazil Puyanawa12.00.0600150See
IRNIran Azeri0.0600100See
SAUSaudi Arabia pop 30.060050See
RUSRussia Transbaikal Territory Buryats11.00.0600150See
USAUSA Caucasian pop 50.0600268See
MYSMalaysia Peninsular Indian10.70.0590271See
INDIndia Delhi0.0590112See
BRABrazil North East Mixed0.0580205See
ESPSpain North Cabuerniga0.058095See
RUSRussia Tuva pop 20.0580169See
BRABrazil Paraná Caucasian11.10.0577641See
CODCongo Kinshasa expatriates living in Belgium11.40.057075See
ITAItaly pop 411.10.05704575See
USAUSA Philadelphia Caucasian11.30.0570141See
USAUSA NMDP European Caucasian0.05631242890See
SENSenegal Dakar11.10.0560112See
ARGArgentina Buenos Aires10.60.0560466See
USAUSA Caucasian pop 40.05581070See
USAUSA African American pop 40.05552411See
DEUGermany pop 310.80.0555111See
KENKenya, Nyanza Province, Luo tribe10.00.0550100See
USAUSA Caucasian Bethesda10.30.0550307See
DEUGermany DKMS - Turkey minority0.05464856See
DEUGermany DKMS - Greece minority0.05461894See
USAUSA NMDP African American pop 20.0542416581See
PRTPortugal North0.054046See
ITAItaly pop 50.0540975See
ISRIsrael Yemenite Jews0.054076See
ITAItaly Bergamo10.90.0540101See
INDIndia Northeast Mathur0.0540155See
HRVCroatia Krk Island Vrbnik0.054028See
USAUSA NMDP Caribean Black0.053333328See
USAUSA NMDP African0.052528557See
USAUSA Caucasian Pittsburgh10.40.0520177See
BRABrazil Mato Grosso do Sul0.0520203See
USAUSA Caucasian10.00.051361655See
SWESweden Northern Sami0.0510154See
PRTAzores Oriental Islands0.051043See
INDIndia Northeast Rastogi0.0510196See
GMBGambia pop 39.50.0508939See
IRNIran Kurd pop 20.050060See
IRNIran Saqqez-Baneh Kurds0.050060See
RUSRussia Siberia Sulamai Ket0.050022See
USAUSA San Francisco Caucasian0.0500220See
CHESwitzerland Sion0.0492832See
COLColombia Sierra Nevada de Santa Marta Arhuaco0.0490107See
MNGMongolia Tsaatan0.0490144See
ITAItaly Central0.0480380See
IRLIreland South9.60.0480250See
CHNChina Urumqi Kazak0.048042See
USAUSA NMDP Hispanic South or Central American0.0478146714See
ENGEngland Bedfordshire9.30.0476354See
DEUGermany DKMS - Italy minority0.04701159See
USAUSA NMDP Southeast Asian0.047027978See
NLDNetherlands UMCU9.40.046964See
COLColombia Bogotá Cord Blood8.70.04651463See
IRNIran Tabriz Azeris0.046497See
USAUSA San Diego9.10.0460496See
TZATanzania Maasai9.20.0459336See
ISRIsrael Non Ashkenazi Jews0.045080See
GRCGreece pop 40.045098See
COLColombia Guajira Peninsula Wayuu0.045088See
ESPSpain Granada0.0450280See
MKDMacedonia pop 30.0440172See
USAUSA NMDP American Indian South or Central America0.04405926See
GRCGreece pop38.50.0434246See
USAUSA NMDP Middle Eastern or North Coast of Africa0.043470890See
RUSRussia Bering Island Aleuts0.0433104See
RUSRussia Chuvash0.043082See
RUSRussia Siberia Negidal0.043035See
RWARwanda Kigali Hutu and Tutsi0.0430281See
USAUSA NMDP North American Amerindian0.042735791See
USAUSA Hispanic pop 20.04201999See
TURTurkey pop 10.0420250See
RUSRussia Siberia Dudinka Nganasan0.042024See
ENGEngland pop 68.50.0420177See
INDIndia North8.20.041885See
USAUSA San Antonio Caucasian0.0405222See
MYSMalaysia Kedah Baling Kensiu0.040025See
CRICosta Rica and Panama Mestizo0.040056See
ARMArmenia combined Regions0.0400100See
MEXMexico Chihuahua Chihuahua City Pop 28.00.039888See
GRCGreece pop 60.0393242See
IRNIran Gorgan0.039064See
SCOScotland Orkney7.70.039099See
MEXMexico Mexico City Mestizo population0.0385143See
COLColombia Bogota and Medellin Mestizo0.038065See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.03801058See
USAUSA NMDP Mexican or Chicano0.0372261235See
NZLNew Zealand Polynesians with Admixed History7.40.037027See
NIRIreland Northern7.20.03701000See
INDIndia Northeast Sunni0.0370188See
BOLBolivia Quechua0.036269See
BRABrazil Southeast Mixed Race7.10.036042See
MEXMexico Veracruz Xalapa7.10.035784See
DZAAlgeria pop 27.00.0356106See
DZAAlgeria Oran0.0350100See
ARGArgentina Mapuche0.035048See
MNGMongolia Khalkha0.0350200See
MARMorocco Nador Metalsa0.035099See
ISRIsrael Ashkenazi Jews pop 20.0350132See
USAUSA African American Bethesda7.00.0350187See
PERPeru Quechua0.034044See
TUNTunisia pop 30.0340104See
IRNIran Fars Parsi0.034073See
LBNLebanon Niha el Shouff0.034061See
ISRIsrael Arab0.0330109See
GRCGreece Crete0.0330135See
COLColombia Providencia Island African0.033030See
LBNLebanon Kafar Zubian0.032094See
COLColombia North Chimila Amerindians0.031947See
ISRIsrael YemenJews0.031715542See
TUNTunisia Gabes0.031595See
USAUSA NMDP Alaska Native or Aleut0.03101376See
ITAItaly North pop 35.10.031097See
MARMorocco Settat Chaouya0.031098See
CHNChina Yunnan Province Han pop 20.0310129See
CHLChile Santiago Mixed6.00.030470See
MEXMexico Mexico City Tlalpan6.10.0303330See
GRCGreece pop 86.00.030183See
MARMorocco Atlantic Coast Chaouya0.030098See
CHNChina Harbin Manchu pop 20.030050See
CUBCuba Mixed0.030078See
SAUSaudi Arabia5.90.029918See
IRNIran pop 20.0292120See
CRICosta Rica African -Caribbean (G)5.80.0290102See
ARGArgentina Rio Negro Mapuche0.029034See
NICNicaragua Mestizo (G)5.80.0290155See
MEXMexico Mexico City Mestizo pop 30.0270256See
KORSouth Korea pop 110.0270149See
NICNicaragua Managua5.10.0269339See
ISRIsrael Ashkenazi Jews pop 30.02674625See
TUNTunisia Gabes Arab0.026096See
USAUSA Hawaii0.026039See
MEXMexico Mexico City Mestizo pop 20.0256234See
MEXMexico Sinaloa Capomos Mayo Yoremes0.025060See
MEXMexico Highlands Mestizos5.00.0250160See
ITAItaly Rome5.00.0250100See
CHNChina Urumqi Han0.025059See
COLColombia West Cauca0.025020See
COLColombia Northwest Choco0.025020See
USAUSA Colorado Univ Cord Blood Bank Asian0.0250100See
USAUSA South Texas Hispanic0.0250194See
NZLNew Zealand Maori with Admixed History4.80.0240105See
NZLNew Zealand Polynesians with Full Ancestry4.80.024021See
ETHEthiopia Oromo0.024083See
CANCanada British Columbia Penutian0.024026See
MNGMongolia Ulaanbaatar Khalkha0.024041See
MYSMalaysia Kedah Kensiu4.80.024021See
INDIndia Northeast Shia0.0240190See
USAUSA Asian pop 20.02381772See
CHNChina Jiangsu Province Han0.0232334See
CHNChina Beijing Shijiazhuang Tianjian Han0.0230618See
KORSouth Korea pop 60.0230800See
JORJordan Amman0.0210146See
CHNChina Wuhan4.10.0210121See
CRICosta Rica Amerindians (G)3.40.0210125See
USAUSA Southern California Mestizo4.10.020773See
ISRIsrael USSR Jews0.020245681See
KORSouth Korea pop 100.02014128See
MYSMalaysia Patani4.00.020025See
INDIndia Northeast Rajbanshi0.020098See
IDNIndonesia Singaporean0.020050See
GRCGreece pop24.10.0200120See
ETHEthiopia Amhara0.020098See
USAUSA South Dakota Lakota Sioux0.0200302See
VNMVietnam Hanoi Kinh0.0200103See
MNGMongolia Khalkha pop 20.0200202See
RUSRussia Siberia Khabarovsk Evenki0.020025See
THAThailand Bangkok pop 20.020050See
ISRIsrael Arab pop 20.019812301See
JPNJapan pop 63.90.0196129See
ISRIsrael Poland Jews0.019313871See
COLColombia North Wiwa El Encanto0.019252See
ISRIsrael Morocco Jews0.019236718See
INDIndia North pop 20.019072See
CHNChina Hong Kong and Singapore0.0190135See
MYSMalaysia Mandailing3.70.019027See
USAUSA NMDP Hawaiian or other Pacific Islander0.018111499See
CHNChina Beijing and Xian0.0180171See
MYSMalaysia Kelantan3.60.018028See
CHLChile Santiago0.0177920See
USAUSA NMDP Korean0.017377584See
USAUSA Mexican American Mestizo pop 30.0170116See
CHNChina Harbin Manchu0.0170172See
CHNChina Harbin Korean0.0170201See
CHNChina Yunnan Province Naxi0.0170118See
MYSMalaysia Champa3.50.017029See
INDIndia Northeast Lachung0.017058See
JPNJapan pop 113.20.016162See
JPNJapan Hyogo3.10.016032See
INDIndia Northeast Mech0.016063See
STPSao Tome Island Angolar0.016032See
MYSMalaysia Peninsular Malay3.20.0158951See
ISRIsrael Georgia Jews0.01574471See
CHNChina pop12.90.0150103See
AUSAustralia Cape York Peninsula Aborigine0.0150103See
ISRIsrael Tunisia Jews0.01479070See
ISRIsrael Bukhara Jews0.01472317See
ISRIsrael Ethiopia Jews0.01465928See
KORSouth Korea pop 22.90.0140207See
ISRIsrael Libya Jews0.01333739See
JPNJapan Hyogo Osaka and Nagano0.0130195See
ISRIsrael USA Jews0.01216058See
LBNLebanon Yuhmur0.012082See
AUSAustralia Kimberly Aborigine0.012041See
ARGArgentina Rosario Toba2.30.012086See
CHNChina Marrow Donor Registry0.0120600See
RUSRussia Siberia Irkutsk Tofalar0.012043See
CHNChina Hubei Han2.40.01183732See
ISRIsrael Argentina Jews0.01144307See
CHNChina Jiangsu Han0.01133238See
ARGArgentina Gran Chaco Mataco Wichi0.011049See
GTMGuatemala Mayan0.0110132See
KORSouth Korea pop 10.0110324See
PAKPakistan Karachi Parsi0.011091See
NZLNew Zealand Maori0.0100200See
MARMorocco Souss Region0.010098See
MEXMexico Guanajuato and Jalisco Mestizo2.00.0100101See
MNGMongolia Oold0.0100104See
ISRIsrael Iranian Jews0.0100101See
FRAFrance West2.00.0100100See
DEUGermany DKMS - China minority0.00981282See
AREUnited Arab Emirates Abu Dhabi0.009652See
ISRIsrael Druze0.00955914See
KORSouth Korea pop 30.0090485See
JPNJapan Kyoto and Osaka0.0090165See
JPNJapan pop 20.0090916See
CHNChina Canton Han0.0090264See
FJIFiji Viti Levu Island0.009057See
RUSRussia Sakhalin Island Nivkhi0.009053See
RUSRussia Siberia Eskimo0.009070See
SGPSingapore Riau Malay0.0090132See
TWNTaiwan Hakka1.80.009055See
GAZGaza Palestinians0.0090165See
ISRIsrael Iraq Jews0.008513270See
USAUSA NMDP Vietnamese0.008443540See
HKGHong Kong Chinese cord blood registry0.00813892See
ISRIsrael Ethiopian Jews0.0080122See
ARGArgentina Gran Chaco Eastern Toba0.0080135See
USAUSA NMDP Chinese0.007899672See
ISRIsrael Kavkazi Jews0.00772840See
CHLChile Mapuche0.007766See
USAUSA NMDP Japanese0.007624582See
CHNChina Zhejiang Han pop 20.0072833See
IDNIndonesia Java Yogyakarta Region0.007062See
JPNJapan Central0.0070371See
USAUSA NMDP Filipino0.006850614See
RUSRussia Belgorod region1.30.0065153See
HKGHong Kong Chinese BMDR0.00647595See
IDNIndonesia Nusa Tenggara Islands0.006049See
BRABrazil Guarani Nandeva0.006086See
BOLBolivia La Paz Aymaras0.006087See
VNMVietnam Hanoi Kinh pop 20.0060170See
VNMVietnam HoaBinh Muong0.006083See
JPNJapan pop 160.005918604See
ISRIsrael Iran Jews0.00588153See
JPNJapan pop 170.00523078See
USAUSA South Dakota Sioux0.0050101See
PERPeru Titikaka Lake Uro0.0050105See
PERPeru Titikaka Lake Uros0.0050105See
TWNTaiwan Minnan pop 11.00.0050102See
THAThailand Kamphaeng Phet0.005097See
KORSouth Korea pop 40.90.0045211See
JPNJapan pop 30.00401018See
JPNJapan pop 40.80.0040525See
THAThailand Northeast0.004066See
THAThailand Northeast pop 20.0040400See
USAUSA Alaska Yupik0.0040252See
RUSRussia Nizhny Novgorod, Russians0.50.00231510See
MEXMexico Chiapas Lacandon Mayans0.0023218See
BRABrazil Kaingang0.0020235See
TWNTaiwan Han Chinese0.0020504See
USAUSA Arizona Gila River Amerindian0.0020492See
TWNTaiwan pop 20.0010364See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000146682See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
THAThailand North Dai Lue0.000096See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
RUSRussia Siberia Chukchi0.000071See
PRYParaguay Aché0.000087See
PRYParaguay Lengua0.000017See
RUSRussia Siberia Kushun Buryat0.000025See
RUSRussia Siberia Ulchi0.000073See
RUSRussia Siberia Chukotka Peninsula Eskimo0.000080See
RUSRussia Siberia Polygus Evenk0.000035See
RUSRussia Siberia North East Kamchatka Koryak0.000092See
RUSRussia Siberia Gvaysugi Udege0.000025See
RUSRussia Siberia NW of Sakhalin Island Nivkh0.000032See
RUSRussia Siberia Chukotka Peninsula Chukchi0.000059See
PHLPhilippines Ivatan0.00.000050See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PNGPapua New Guinea Lowland0.000047See
PNGPapua New Guinea Lowland Wosera0.000079See
PNGPapua New Guinea Highland0.000094See
NCLNew Caledonia0.000065See
WSMWestern Samoa and Tokelau0.000051See
WSMSamoa pop20.000050See
BRABrazil Guarani M bya0.000093See
BRABrazil East Amazon0.000041See
BRABrazil Central Plateau Xavante0.000074See
BRABrazil Vale do Ribeira Quilombos0.10.0000144See
CANCanada British Columbia Athabaskan0.000062See
ARGArgentina Gran Chaco Western Toba Pilaga0.000019See
ARGArgentina Chubut Tehuelche0.000023See
ARGArgentina Salta Wichi0.000024See
COKCook Islands Rarotonga0.000078See
COKCook Islands0.000050See
MNGMongolia Hoton0.000085See
MNGMongolia Tarialan Khoton0.000085See
IDNIndonesia Moluccan Islands0.000024See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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